scholarly journals Obesity and Density of the Crystalline Lens: Revisiting a Growing Dilemma

2017 ◽  
Vol 2 (1) ◽  
pp. 1-8 ◽  
Author(s):  
Seyed-Farzad Mohammadi ◽  
Mohsen Afarideh ◽  
Hadi Z. Mehrjardi ◽  
Sara Mirhadi
Keyword(s):  
Adult Population ◽  
Crystalline Lens ◽  
Population Group ◽  
Protective Role ◽  
P Value ◽  
Cross Sectional ◽  
Optical Lens ◽  
Age Related ◽  
Lens Density

Background/Aims: Obesity is believed to accelerate age-related cataractogenesis through various biomechanisms. On the contrary, there are also studies advocating the protective role of obesity against the cataract formation process. We investigate the correlation of body mass index (BMI) as a measure for obesity with crystalline optical lens density and opacity in a healthy adult population. Methods: In a cross-sectional setting, 93 consecutive disease-free adult individuals who were working staff of a university-based hospital were assessed for the association between crystalline lens density and opalescence [measured by the objective Pentacam HR lens densitometry and subjective Lens Opacity Classification System III (LOCS III), respectively] with the degree of obesity as defined by BMI. Results: LOCS III and crystalline lens density readings were positively correlated [Spearman rho CC (p value) = 0.224 (0.034)]. However, we found neither LOCS III nor crystalline lens density to be correlated with BMI [Spearman rho CC = −0.008 (p = 0.943) and −0.062 (p = 0.560), respectively]. Conclusions: Results from the present study indicate a lack of association between obesity and densitometry of the crystalline in the adult population group. Further studies are required to confirm the order of causality and pathogenesis of this finding.

A Possible Role for the Antioxidants Lutein and Zeaxanthin in Protecting against Age-Related Increases in Lens Density

Perception ◽  
1997 ◽  
Vol 26 (1_suppl) ◽  
pp. 166-166
Author(s):  
B R Hammond ◽  
J E Náñez
Keyword(s):  
Light Exposure ◽  
Latency Period ◽  
Crystalline Lens ◽  
Epidemiological Data ◽  
Protective Role ◽  
Older Individuals ◽  
Age Related ◽  
Number Of Factors ◽  
Relationship Of

Epidemiological data have identified a number of factors that influence risk of developing age-related cataract (ARC). For instance, factors that promote (eg smoking and light exposure) and factors that protect (eg antioxidants) against oxidative stress to the crystalline lens appear to increase and decrease risk of ARC, respectively. Although biochemical studies consistently support a protective role for antioxidants, the epidemiological data are inconsistent. Since ARC is a condition with a protracted latency period, it is possible that the inconsistencies present in the epidemiological literature may be due to the focus on cataractous patients. We focused on the lens health of individuals prior to cataract. Lens health was determined by measuring the optical density (OD) of the lens with a psychophysical technique. OD characterises many of the biochemical changes of the lens and is part of many systems used to classify ARC. Variance in lens OD, stratified by age, was examined for its relationship to variables thought to be important to the etiology of ARC. We report results for the relationship of lens OD to the antioxidants lutein and zeaxanthin (L and Z). For older individuals (>48 years) we noted a significant inverse relationship between dietary intake of L and Z and lens OD ( n=39, r=−0.34, p<0.015). This was not the case for younger individuals (24 – 36 years). This relationship is increased when L and Z are measured directly in the retina is a psychophysical technique. For older individuals, retinal L and Z (ie macular pigment) are inversely related to lens OD ( n=51, r=-0.47, p<0.001). These data are consistent with a role of L and Z in protecting against age-related increases in the OD of the crystalline lens.

HUBUNGAN PERAN KADER POSYANDU DENGAN STATUS GIZI BALITA

2018 ◽  
Vol 9 (02) ◽  
pp. 192
Author(s):  
Wiwid Wahyuningsih ◽  
Atik Setiyaningsih
Keyword(s):  
Nutritional Status ◽  
Total Sample ◽  
Nutrition Status ◽  
P Value ◽  
Chi Square ◽  
Cross Sectional ◽  
Central Java ◽  
Good Nutrition ◽  
Nutritional Status Of Children

ABSTRAKLatar Belakang : Keberadaan kader di posyandu sebagai salah satu sistem penyelenggarakan pelayanan sangat dibutuhkan. Mereka adalah ujung tombak  pelayanan kesehatan yang merupakan kepanjangtanganan puskesmas Jawa Tengah tahun 2011 jumlah gizi kurang 5,35% dan gizi buruk 0,10%. Untuk Kabupaten Semarang dari 23.562 balita yang ditimbang pada tahun 2011 gizi lebih 1,13%, gizi baik 93,51%, gizi kurang 4,86% dan gizi buruk 0,49% (DepKes Prov Jateng, 2011). Tujuan Penelitian : Penelitian ini bertujuan untuk mengetahui hubungan peran kader posyandu dengan status gizi balita. Metode Penelitian : Desain penelitian ini adalah survey analitik dengan menggunakan pendekatan cross sectional. Populasi dalam penelitian ini adalah seluruh balita di Posyandu Mawar di Desa Gedangan sejumlah 40 responden, dengan teknik total sampling dan analisa data chi square. Hasil Penelitian : Hasil perhitungan chi square di peroleh X² hitung 10.644 pada df=4, P.value 0.031 dimana probabilitas lebih kecil dari level of significant 5 % (0,001 < 0,05) berarti Ha diterima dan Ho ditolak. Kesimpulan : ada hubungan antara peran kader posyandu dengan status gizi pada balita.Kata Kunci : peran kader , status gizi balitaCADERE ROLE RELATIONSHIP WITH NUTRITIONAL STATUS OF CHILDREN POSYANDUABSTRACTBackground : posyandu cadre in Existence as one of the 56th's service system is urgently needed. They are the tip of the Spear is a kepanjangtanganan health services clinics in Central Java in 2011 the amount of nutrition less 5.35% 0.10% and malnutrition. To Semarang from 23.562 toddler who weighed in 2011 more nutritional 1.13%, 93,51%, good nutrition nutrition less 4.86% and 0.49% poor nutrition (Department of Health Central Java Prov., 2011). Objective : the research aims to find out the relationship role of posyandu cadre with the nutritional status of children. Methods : the design of this research is a survey using the analytic approach of cross sectional. The population in this study are all the toddlers at the Rose in the village of Posyandu Gedangan some 38 respondents, with total sample techniques and data analysis a chi square. The results :. The chi square calculation results in getting X ² count 10.644 on df = 4, P. value 0.031 where probability is smaller than the level of significant 5% (0.001 < 0.05) mean Ha Ho accepted and rejected. Conclusion : there is a connection between the role of cadres of posyandu with nutritional status on toddlers.Keywords : the role of cadres, toddler nutrition status

scholarly journals Memory and Spatial Cognition in Breast Cancer Patients Undergoing Adjuvant Endocrine Therapy

Breast Care ◽  
2016 ◽  
Vol 11 (4) ◽  
pp. 240-246 ◽  
Author(s):  
Ute Berndt ◽  
Bernd Leplow ◽  
Robby Schoenfeld ◽  
Tilmann Lantzsch ◽  
Regina Grosse ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Spatial Cognition ◽  
Verbal Memory ◽  
Multiple Testing ◽  
Local Therapy ◽  
Protective Role ◽  
P Value ◽  
Breast Cancer Patients ◽  
Cross Sectional ◽  
Switch Group

Introduction: It is generally accepted that estrogens play a protective role in cognitive function. Therefore, it can be expected that subtotal estrogen deprivation following aromatase inhibition will alter cognitive performance. Methods: In a cross-sectional study we investigated 80 postmenopausal women with breast cancer. Memory and spatial cognition were compared across 4 treatment groups: tamoxifen only (TAM, n = 22), aromatase inhibitor only (AI, n = 22), TAM followed by AI (‘SWITCH group', n = 15), and patients with local therapy (LT) only (surgery and radiation, n = 21). Duration of the 2 endocrine monotherapy arms prior to the assessment ranged from 1 to 3 years. The ‘SWITCH group' received 2-3 years TAM followed by at least 1 year and at most 3 years of AI. Memory and spatial cognition were investigated as planned comparisons. Investigations of processing speed, attention, executive function, visuoconstruction and self-perception of memory were exploratory. Results: With regard to general memory, AI patients performed significantly worse than the LT group (p = 0.013). Significant differences in verbal memory did not remain significant after p-value correction for multiple testing. We found no significant differences concerning spatial cognition between the groups. Conclusion: AI treatment alone significantly impairs general memory compared to the LT group.

scholarly journals The Protective Role of Sestrin2 in Atherosclerotic and Cardiac Diseases

2021 ◽  
Vol 22 (3) ◽  
pp. 1200
Author(s):  
Yoshimi Kishimoto ◽  
Kazuo Kondo ◽  
Yukihiko Momiyama
Keyword(s):  
Oxidative Stress ◽  
Protective Role ◽  
Chronic Inflammatory Disease ◽  
Atherosclerotic Disease ◽  
Cardiac Diseases ◽  
Compensatory Response ◽  
Age Related ◽  
Anti Oxidant ◽  
Progression Of Atherosclerosis

Atherosclerotic disease, such as coronary artery disease (CAD), is known to be a chronic inflammatory disease, as well as an age-related disease. Excessive oxidative stress produced by reactive oxygen species (ROS) contributes to the pathogenesis of atherosclerosis. Sestrin2 is an anti-oxidant protein that is induced by various stresses such as hypoxia, DNA damage, and oxidative stress. Sestrin2 is also suggested to be associated with aging. Sestrin2 is expressed and secreted mainly by macrophages, endothelial cells, and cardiomyocytes. Sestrin2 plays an important role in suppressing the production and accumulation of ROS, thus protecting cells from oxidative damage. Since sestrin2 is reported to have anti-oxidant and anti-inflammatory properties, it may play a protective role against the progression of atherosclerosis and may be a potential therapeutic target for the amelioration of atherosclerosis. Regarding the association between blood sestrin2 levels and atherosclerotic disease, the blood sestrin2 levels in patients with CAD or carotid atherosclerosis were reported to be high. High blood sestrin2 levels in patients with such atherosclerotic disease may reflect a compensatory response to increased oxidative stress and may help protect against the progression of atherosclerosis. This review describes the protective role of sestrin2 against the progression of atherosclerotic and cardiac diseases.

The Protective Role of Exercise Against Age-Related Neurodegeneration

2021 ◽  
pp. 101543
Author(s):  
Alyson L. Sujkowski ◽  
Luke Hong ◽  
R.J. Wessells ◽  
Sokol V. Todi
Keyword(s):  
Protective Role ◽  
Age Related

Role of susceptibility weighted imaging (SWI) in assessment of intra axial brain neoplasms in adults

QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Pasant Mohamed Abo-Elhoda Darwish Mohamed Abo-Elhoda ◽  
Hesham Mahmoud Ahmed Mansour ◽  
Yosra Abdelzaher Abdullah ◽  
Eman Ahmed Fouad Darwish
Keyword(s):  
Brain Neoplasms ◽  
Tumor Size ◽  
Venous Blood ◽  
Brain Parenchyma ◽  
P Value ◽  
Susceptibility Weighted Imaging ◽  
Low Grade ◽  
Chi Square ◽  
Cross Sectional

Abstract Background Susceptibility weighted imaging (SWI) is a 3D gradient-echo MR technique that is based on blood oxygen level dependent (BOLD) induced phase effects between the venous blood and the surrounding brain parenchyma. SW-MR imaging allows for noninvasive visualization of small veins at submillimeter resolution and, therefore, is used to depict venous architecture in brain lesions. The extreme sensitivity of SWI for the detection of neovascularity (venous blood), haemorrhage, and calcification has been an indispensable tool for characterization of the internal architecture of brain tumours. Objectives Is to evaluate the role of Susceptibility weighted imaging in assessment of adults Intra axial brain Neoplasms, and its ability to characterize them into high and low grade lesions in comparison to histopathology which will be used as gold standard. Methods A cross sectional study including 31 patients suspecting intracranial brain neoplasm radiologically and clinically, conducted at Private center, the patients were investigated using Siemens machine Magnetom Skyra 3T, the period was between January 2018 till the end of June 2019 . Results Our study included 31 patients. Including 15 female and 16 male patients, with the patient’s age ranging from 20 to 68 years old with median 48 years old ranging from 35.75 (25% percentile) to 58.75 (75% percentile). Among total cases, there were 8 patients with grade 2 glioma, 10 patients with grade 3 glioma and 6 patients with grade 4 glioma, 2 patients with lymphoma and 5 patients with brain metastasis (1 lung cancer and 4 breast cancer). All the patients were evaluated with MRI including SWI sequence with special comment on the number of the intratumoral susceptibility signal (ITSS), the size of the ITSS, its morphology as well as the ratio of the ITSS to the tumor size, which were then correlated with the patient histopathological results obtained later. The study revealed that the best parameter to accurately grade the tumor is the number of ITSS within the lesion with P value 0.001, followed by the size of the ITSS with P value 0.002 and Pearson Chi-Square value equals 20.6, while the lowest one was the ratio of the ITSS to the tumor size with P value 0.002 Pearson Chi-Square value equals 17.3. Our study showed that the morphology alone was not able to accurately grade the tumor with P value 0.007 ( Not significant) Conclusion SWI using 3T MR system provides quite useful information for preoperative tumor grading. There seems to be a strong correlation between pathological grading and that assessed with SWI.

scholarly journals Hubungan peran Keluarga dengan Perilaku Seks Pranikah Pada Remaja SMP Negeri 5 Ungaran

2021 ◽  
Vol 2 (2) ◽  
pp. 103
Author(s):  
Umi Setyoningrum ◽  
Liyanovitasari Liyanovitasari
Keyword(s):  
Sexual Behavior ◽  
High School Students ◽  
Junior High School ◽  
Negative Impact ◽  
P Value ◽  
Family Roles ◽  
School Students ◽  
Cross Sectional ◽  
Premarital Sexual

Pre-marital sexual behavior in adolescents is increasing and has a negative impact on the development and growth of adolescents. This was influenced by several factors including the role of families that did not function optimally. If in a family, the teenagers get less attention, then they will act recklessly because they feel there is no prohibition from parents. There is no form of advice, prohibition or punishment if a mistake is made, this proves the lack of attention of parents to adolescents. Low supervision ofadolescent activities will have an impact on adolescents’ behavior. This study aims to determine the correlation between family roles and premarital sexual behavior in junior high school students. This research was cross sectional designand it was carried out by measuring and observing variables at the same time. The number of samples as many as 185 participants were taken by purposive proportional random sampling technique. This study found that there is correlation between family roles and premarital sexual behavior in adolescents with p value 0.029. parents role are needed in adolescent relationship with peer and guide them to choose good friends.Keywords :The Role of Family, Premarital Sexual Behavior in Adolescents

scholarly journals Penggunaan media sosial dan peran orang tua terhadap kejadian pernikahan dini

2020 ◽  
Vol 14 (3) ◽  
pp. 445-451
Author(s):  
Asnuddin Asnuddin ◽  
Asrini Mattrah
Keyword(s):  
Social Media ◽  
Cross Sectional Study ◽  
Early Marriage ◽  
P Value ◽  
Chi Square ◽  
Cross Sectional ◽  
Chi Square Test ◽  
Role Of Parents ◽  
Use Of Social Media

Social media use: The role of parents' perceptions about social media impact in early marriageBackground: Early marriage is a marriage that is conducted at adolescence, the factors causing early marriage are socio-cultural factors, economic pressure, level of education, difficulty in getting a job, social media, religion and views and beliefsPurpose: To find out the influence of social media and the role of parents on the incidence of early marriageMethod: A quantitative research using descriptive analytical research method with cross sectional study design with variable use of social media with the criteria for the results "active and inactive". For the variable of the role of parents with 2 outcome criteria, namely "influential and not influential". And for the variable incidence of early marriage, there are 2 criteria, namely age 14-16 years and age 17-19 years, the questionnaire used has been through the validity of previous researchers. Then the results of the data obtained were analyzed in the SPSS program using the Chi Square testResults: From the Chi Square test results for social media variables obtained p value = 0.001, then the value of p = 0.001 <0.05 (α) while the role of parents variable Chi Square test results obtained p value = 0.022, therefore the value of p = 0.022 <0.05 (α).Conclusion: Based on the results of the study it can be concluded that, there is a significant influence between the use of social media and the role of parents in the event of early marriage Keywords: Social media; Parents, Early marriagePendahuluan: Pernikahan usia dini adalah perkawinan yang dilakukan pada usia remaja, faktor penyebab pernikahan usia dini adalah faktor sosial budaya, desakan ekonomi, tingkat pendidikan, sulit mendapat pekerjaan, media sosial, agama serta pandangan dan kepercayaan.Tujuan: Untuk mengetahui pengaruh media sosial dan peran orang tua terhadap kejadian pernikahan dini di Kecamatan Marioriawa Kabupaten Soppeng Metode: Penelitian kuantitatif dengan menggunakan metode penelitian deskriptif analitik dengan rancangan cross sectional study dengan variabel penggunaan media sosial dengan kriteria hasil “aktif dan tidak aktif”. Untuk variabel peran orang tua dengan 2 kriteria hasil yaitu “berpengaruh dan tidak berpengaruh”. Dan untuk variabel kejadian pernikahan dini ada 2 kriteria  yaitu umur 14-16 tahun dan umur 17-19 tahun,  kuesioner yang di gunakan sudah melalui uji validitas peneliti sebelumnya. Kemudian hasil data yang di dapatkan dianalisis di program SPSS dengan menggunakan uji Chi SquareHasil: Dari hasil uji Chi Square untuk variabel media sosial didapatkan nilai p=0,001, maka nilai p=0.001<0.05 (α) sedangkan variabel peran orang tua hasil uji Chi Square didapatkan nilai p=0,022, oleh karena itu nilai p=0.022<0.05 (α).Simpulan: Berdasarkan hasil penelitian dapat di simpulkan bahwa, Ada pengaruh yang signifikan antara penggunaan media sosial dan peran orang tua terhadap kejadian pernikahan dini

scholarly journals Determinan Kepatuhan Minum Obat Pasien Tuberkulosis Paru

2019 ◽  
Vol 1 (2) ◽  
pp. 176-185
Author(s):  
Christine Vita Gloria ◽  
Zulmeliza Rasyid ◽  
Sherly Vermita W ◽  
Elmia Kursani ◽  
Bizanti Umayyah
Keyword(s):  
Pulmonary Tuberculosis ◽  
Health Center ◽  
Family Support ◽  
Health Workers ◽  
Treatment Compliance ◽  
P Value ◽  
Cross Sectional ◽  
Tuberculosis Patients ◽  
Lung Tuberculosis

This study aims to see whether the determinants are related to treatment compliance for pulmonary tuberculosis patients at the 2019 health center. This type of research is a quantitative observational cross-sectional design. The results showed that with a P value of 0.05, there was a significant relationship between knowledge (P value = 0.005 and POR = 14.276), attitudes (P value = 0.506 and POR = 1.615), family support (P value = 0.038 and POR = 1,961), the role of health workers (P values = 0.026 and POR = 4.440), with medication adherence for pulmonary tuberculosis patients. Conclusions, of the 4 variables there are 3 variables related to adherence to taking pulmonary TB drugs in the Work Area of the Siak Hulu II Health Center, namely knowledge, family support, and the role of health workers and 1 unrelated variable, attitude.   Keywords: Obedience, Medicine, Lung Tuberculosis

scholarly journals Hubungan Beban Kerja Perawat Dengan Peran Perawat Anak Dalam Pendampingan Terapi Bermain

JKEP ◽  
2019 ◽  
Vol 4 (2) ◽  
pp. 104-113
Author(s):  
Ririn Nur Indah sari ◽  
Sari Windyastuti ◽  
Tri Sakti Widyaningsih
Keyword(s):  
Play Therapy ◽  
Sampling Technique ◽  
Rank Test ◽  
P Value ◽  
Test Statistic ◽  
Cross Sectional ◽  
Test Analysis ◽  
Spearman Rank ◽  
Nurse Workload

Nurse workload is very influential on child play therapy assistance caused by workload excessive workload, lack of facilities and infrastructure, nothing schedule for play therapy and the number of nurses  only 18 nurses, According to theory Gilles with the number of beds 34 needed 29 nurses. The purpose of this research is to know the Relationship of Nurse Workload with The Role of Child’s Nurse in Mentoring Play Therapy in Room Dahlia RSUD Dr. H Sewondo Kendal. This type of research is descriptive correlation with cross sectional. The sampling technique with total sampling, a sample is 18 respondents. Retrieval data using questionnaires and then tested into Spearman Rank test statistic. Based on research found 10 respondents (55,6%) have hard workload and 8 respondents (44,4%) have a light workload. The role of nurses in good categories 5 respondents (27,8%) and categories less is 13 respondents (72,2%). From result of Spearman Rank test analysis, get result of coefficient correlation value -868 in category very strong and obtained p value = 0,000 < 0,05 it’s mean Ha accepted and H0 rejected. There is a relantionship between the nurses workload with the role of child nurses in mentoring play therapy.

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