Kidney Cancer Linked to Chronic Hepatitis in the Asia-Pacific: A Population-Based Analysis

2016 ◽  
Vol 45 (1) ◽  
pp. 22-31 ◽  
Author(s):  
Yu-Shan Lin ◽  
Chih-Ching Yeh ◽  
Yen-Chung Lin ◽  
Chien-Tien Su ◽  
Fung-Chang Sung ◽  
...  

Background: The association of renal cancer with viral hepatitis infection remains unclear. Using an insurance data set, this population-based case-control study evaluated the association of renal cancer with chronic hepatitis virus infection in an endemic area of hepatitis B virus (HBV) and hepatitis C virus (HCV) infection. Methods: We enrolled 17,747 patients with renal cancer during the period from 2000 to 2011 from the National Health Insurance Research Database of Taiwan. The control group comprised 35,494 randomly selected people without renal cancer matched by age and gender to the patients in the study group. ORs were calculated to assess the association of chronic hepatitis virus infection with renal cancer by using logistic regression analysis. Results: Renal cancer was associated with HBV and HCV infection (OR 1.38, 95% CI 1.24-1.54; OR 1.24, 95% CI 1.07-1.44, respectively). An analysis stratified by gender and age revealed that young male HBV carriers had a higher risk of renal cancer compared with men without viral hepatitis (age <55 years: OR 1.94, 95% CI 1.57-2.39; 55≤ age <64 years: OR 1.40, 95% CI 1.05-1.86). Male HCV-infected patients aged <55 years (OR 1.90, 95% CI 1.11-3.26) and female HCV carriers aged between 55 and 64 years (OR 1.59, 95% CI 1.00-2.53) had a significantly higher risk of renal cancer compared with their counterparts. Conclusions: Renal cancer is significantly associated with chronic hepatitis infection, particularly in younger HBV-infected men.

PLoS ONE ◽  
2016 ◽  
Vol 11 (8) ◽  
pp. e0161958 ◽  
Author(s):  
Chih-Ching Yeh ◽  
Wen-Chang Wang ◽  
Chien-Sheng Wu ◽  
Fung-Chang Sung ◽  
Chien-Tien Su ◽  
...  

Clinics ◽  
2011 ◽  
Vol 66 (12) ◽  
pp. 2055-2061 ◽  
Author(s):  
Chung-Jen Teng ◽  
Han-Tsung Liu ◽  
Chun-Yu Liu ◽  
Chi-Hsiu Hsih ◽  
Jih-Tung Pai ◽  
...  

2021 ◽  
Vol 3 (3) ◽  
Author(s):  
Hiroshi Okano ◽  
Hiroki Asakawa ◽  
Kenji Nose ◽  
Satomi Tsuruga ◽  
Tomomasa Tochio ◽  
...  

2014 ◽  
Vol 10 (4-5) ◽  
pp. 405
Author(s):  
A. A. Ostanin ◽  
E. L. Gelfgadt ◽  
M. V. Shipunov ◽  
E. Ya. Shevela ◽  
E. V. Kurganova ◽  
...  

2016 ◽  
Vol 2 (1) ◽  
pp. 46
Author(s):  
Mia Ratwita Andarsini

Patients of thalassemia who are conventionally treated by a regular transfusion regimen, are at a risk of developing transfusion transmitted infections, including hepatitis. The present study was conducted to evaluate the prevalence of hepatitis virus infection in repeated transfused thalassemia patients. A total of 83 patients of thalassemia who had received at least 10 transfusions were tested for HBs Ag, anti HBs and anti-HCV using ELISA. Amongst these patients, HBs Ag, anti HBs and anti HBC were detected in 1.2%, 26.5% and 12% patients respectively. the prevalence of HBV and HCV infection were in agreement with the findings in other study.


1985 ◽  
Vol 22 (4) ◽  
pp. 338-343 ◽  
Author(s):  
L. Roth ◽  
J. M. King ◽  
W. E. Hornbuckle ◽  
H. J. Harvey ◽  
B. C. Tennant

The livers of 16 woodchucks with naturally acquired chronic infection with woodchuck hepatitis virus were examined both grossly and histologically in 14 biopsy specimens and seven necropsy specimens. Fifteen woodchucks had lesions characteristic of chronic hepatitis; ten of these had chronic active hepatitis, four had chronic persistent hepatitis, and one had cirrhosis with nodular regeneration. In one woodchuck there was massive hepatic necrosis attributed to infection with an unclassified protozoan. Thirteen woodchucks had primary hepatocellular carcinoma. Metastasis to the lung was observed in only one woodchuck. These results were compared to liver lesions in 149 woodchuck hepatitis virus-negative woodchucks. Chronic hepatitis comparable to that associated with woodchuck hepatitis virus infection was not observed in woodchuck hepatitis virus-negative woodchucks although in one, a single, small hepatocellular adenoma was found.


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