The Role of Nephrologist in the Intensive Care Unit

2016 ◽  
Vol 43 (1-3) ◽  
pp. 78-81 ◽  
Author(s):  
Zoltán H. Endre
Keyword(s):  
Chronic Kidney Disease ◽  
Intensive Care Unit ◽  
Acute Kidney Injury ◽  
Intensive Care ◽  
Kidney Injury ◽  
Renal Diseases ◽  
Continuing Care ◽  
Electrolyte Disorders

Participation by nephrologists is needed in most intensive care units, even when such units are ‘closed'. This participation should assist with diagnosis and management of intrinsic and complex renal diseases such as vasculitis, complex metabolic and electrolyte disorders including hyponatremia, and acute kidney injury (AKI) with and without underlying chronic kidney disease (CKD). Early nephrologist involvement will also facilitate transition to continuing care and follow-up after an episode of AKI, but may also assist in avoiding dialysis where treatment is futile. Management of AKI by intensivists should be in partnership with nephrologists to oversight and hopefully to minimize progression to CKD.

scholarly journals MP234PREDICTIVE VALUE OF CHRONIC KIDNEY DISEASE (CKD) IN ACUTE KIDNEY INJURY (AKI) PRESENTATION IN AN INTENSIVE CARE UNIT (ICU) OF A LOCAL HOSPITAL

2016 ◽  
Vol 31 (suppl_1) ◽  
pp. i417-i418
Author(s):  
José María Peña Porta ◽  
María Esther Esteban Ciriano ◽  
Carmen Vicente de Vera Floristán ◽  
José Manuel Vicente de Vera Floristán ◽  
John Ros Añón ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Intensive Care Unit ◽  
Acute Kidney Injury ◽  
Intensive Care ◽  
Kidney Disease ◽  
Kidney Injury ◽  
Local Hospital

scholarly journals IL-20 in Acute Kidney Injury: Role in Pathogenesis and Potential as a Therapeutic Target

2020 ◽  
Vol 21 (3) ◽  
pp. 1009
Author(s):  
Tian-Yu Lin ◽  
Yu-Hsiang Hsu
Keyword(s):  
Chronic Kidney Disease ◽  
Acute Kidney Injury ◽  
Risk Factor ◽  
Renal Fibrosis ◽  
Inflammatory Mediator ◽  
Kidney Diseases ◽  
Kidney Injury ◽  
Renal Diseases ◽  
Pro Inflammatory Cytokines

Acute kidney injury (AKI) causes over 1 million deaths worldwide every year. AKI is now recognized as a major risk factor in the development and progression of chronic kidney disease (CKD). Diabetes is the main cause of CKD as well. Renal fibrosis and inflammation are hallmarks in kidney diseases. Various cytokines contribute to the progression of renal diseases; thus, many drugs that specifically block cytokine function are designed for disease amelioration. Numerous studies showed IL-20 functions as a pro-inflammatory mediator to regulate cytokine expression in several inflammation-mediated diseases. In this review, we will outline the effects of pro-inflammatory cytokines in the pathogenesis of AKI and CKD. We also discuss the role of IL-20 in kidney diseases and provide a potential therapeutic approach of IL-20 blockade for treating renal diseases.

The role of advanced oxidation protein products in intensive care unit patients with acute kidney injury

2010 ◽  
Vol 25 (4) ◽  
pp. 605-609 ◽  
Author(s):  
Paolo Lentini ◽  
Massimo de Cal ◽  
Dinna Cruz ◽  
Alexandra Chronopoulos ◽  
Sachin Soni ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Acute Kidney Injury ◽  
Intensive Care ◽  
Kidney Injury ◽  
Advanced Oxidation ◽  
Advanced Oxidation Protein Products

scholarly journals Role of Uric Acid Albumin Ratio in Predicting Development of Acute Kidney Injury and Mortality in Intensive Care Unit Patients

2019 ◽  
Vol 28 (3) ◽  
pp. 160-167
Author(s):  
Hacı Hasan Yeter ◽  
◽  
Damla Eyupoglu ◽  
Tural Pasayev ◽  
Sila Cetik ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Acute Kidney Injury ◽  
Uric Acid ◽  
Intensive Care ◽  
Kidney Injury ◽  
Albumin Ratio

scholarly journals Deprivation and kidney disease—a predictor of poor outcomes

2019 ◽  
Vol 13 (2) ◽  
pp. 128-132
Author(s):  
Greg D Guthrie ◽  
Samira Bell
Keyword(s):  
Chronic Kidney Disease ◽  
Acute Kidney Injury ◽  
Kidney Disease ◽  
Renal Disease ◽  
Kidney Injury ◽  
Renal Diseases ◽  
Confounding Factors ◽  
Growing Body ◽  
Poor Outcomes

Abstract There is a growing body of evidence for the role of deprivation in a broad spectrum of diseases including renal disease. Deprivation has been demonstrated to be associated with poorer outcomes across a range of renal diseases including acute kidney injury (AKI), chronic kidney disease and transplantation. In this issue of Clinical Kidney Journal, Hounkpatin et al. describe the association of socioeconomic deprivation with incidence, mortality and resolution of AKI in a large UK cohort. Investigating deprivation as a factor influencing either incidence or outcome of disease is challenging due to variations in measures of deprivation used and other confounding factors that may be contributing to the observed differences. In this editorial, we review the current literature examining the role of deprivation in renal disease.

scholarly journals Fenoldopam Mesylate: A Narrative Review of Its Use in Acute Kidney Injury

2019 ◽  
Vol 20 (5) ◽  
pp. 366-375 ◽  
Author(s):  
Annalisa Noce ◽  
Giulia Marrone ◽  
Valentina Rovella ◽  
Andrea Busca ◽  
Caterina Gola ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Acute Kidney Injury ◽  
Intensive Care ◽  
Kidney Injury ◽  
Protective Role ◽  
Small Samples ◽  
Hospital Treatment ◽  
Postoperative Aki ◽  
Positive Results

Background: Fenoldopam mesylate is a selective agonist of DA-1 receptors. It is currently used for the in-hospital treatment of severe hypertension. DA-1 receptors have high density in renal parenchyma and for this reason, a possible reno-protective role of Fenoldopam mesylate was investigated. Method: We examined all studies regarding the role of Fenoldopam mesylate in Acute Kidney Injury (AKI); particularly, those involving post-surgical patients, intensive care unit patients and contrastinduced nephropathy. Results: Fenoldopam mesylate was found to be effective in reducing the onset of postoperative AKI, when used before the development of the kidney damage. Positive results were also obtained in the management of intensive care unit patients with AKI, although the clinical studies investigated were few and conducted on small samples. Conclusion: Conflicting results were achieved in contrast-induced nephropathy.

Acute kidney injury in the pediatric intensive care unit: outpatient follow-up

2021 ◽  
Author(s):  
Cal Robinson ◽  
Erin Hessey ◽  
Sophia Nunes ◽  
Marc Dorais ◽  
Rahul Chanchlani ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Acute Kidney Injury ◽  
Intensive Care ◽  
Pediatric Intensive Care Unit ◽  
Kidney Injury ◽  
Pediatric Intensive Care

scholarly journals The Role of Dexmedetomidine for the Prevention of Acute Kidney Injury in Critical Care

2021 ◽  
pp. 97-106
Author(s):  
Gion Ruegg ◽  
Nora Luethi ◽  
Luca Cioccari
Keyword(s):  
Experimental Data ◽  
Intensive Care Unit ◽  
Acute Kidney Injury ◽  
Clinical Trials ◽  
Renal Function ◽  
Critical Care ◽  
Intensive Care ◽  
Kidney Injury ◽  
Ischaemia Reperfusion

Acute kidney injury (AKI) occurs in up to 50% of patients admitted to the intensive care unit and is associated with increased mortality. Currently, there is no effective pharmacotherapy for prevention or treatment of AKI. In animal models of sepsis and ischaemia-reperfusion, α2-agonists like dexmedetomidine (DEX) exhibit anti-inflammatory properties and experimental data indicate a potential protective effect of DEX on renal function. However, clinical trials have yielded inconsistent results in critically ill patients. This review discusses the pathophysiological mechanisms involved in AKI, the renal effects of DEX in various intensive care unit-related conditions, and summarises the available literature addressing the use of DEX for the prevention of AKI.

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