scholarly journals Swept-Source Optical Coherence Tomography Detecting Intraoperative Acute Descemet's Fold Formation

2016 ◽  
Vol 7 (2) ◽  
pp. 354-358
Author(s):  
Yu Ichioka ◽  
Akihito Uji ◽  
Nagahisa Yoshimura
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Coherence ◽  
Swept Source ◽  
En Face Oct ◽  
En Face ◽  
Descemet's Membrane ◽  
Descemet’S Membrane ◽  
Oct Imaging ◽  
Fold Formation ◽  
B Scan Images

Background: To present an intraoperative acute Descemet’s fold formation using swept-source optical coherence tomography (SS-OCT) imaging. Case Report: A 67-year-old man complaining of reduced visual acuity in the left eye. A 25-gauge pars plana vitrectomy combined with phacoemulsification cataract surgery was performed to remove the vitreomacular traction. When hydro-sealing was performed, striae rapidly spread in the cornea. SS-OCT B-scan images performed on postoperative day 1 revealed a wavy Descemet’s membrane that might correspond to Descemet’s folds. Pairs of hypo- and hyperreflective narrow lesions running from the wavy Descemet’s membrane to almost half of the thickness of the whole cornea were observed. En face OCT imaging clearly showed the stromal fold, which continuously spread from the Descemet’s fold. Conclusion: The stromal fold might be due to the focal bulge of the stroma posteriorly caused by the rapid volume increase of the stroma which could push Descemet’s membrane posteriorly, thereby forming a wavy Descemet’s membrane layer.

Feasibility and Clinical Utility of Ultra-Widefield–Navigated Swept-Source Optical Coherence Tomography Imaging

2021 ◽  
pp. 247412642199733
Author(s):  
Kyle D. Kovacs ◽  
M. Abdallah Mahrous ◽  
Luis Gonzalez ◽  
Benjamin E. Botsford ◽  
Tamara L. Lenis ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Clinical Utility ◽  
Clinical Decision Making ◽  
Imaging System ◽  
Imaging Modality ◽  
Case Series ◽  
Subretinal Fluid ◽  
Optical Coherence ◽  
Swept Source ◽  
Oct Imaging

Purpose: This work aims to evaluate the clinical utility and feasibility of a novel scanning laser ophthalmoscope-based navigated ultra-widefield swept-source optical coherence tomography (UWF SS-OCT) imaging system. Methods: A retrospective, single-center, consecutive case series evaluated patients between September 2019 and October 2020 with UWF SS-OCT (modified Optos P200TxE, Optos PLC) as part of routine retinal care. The logistics of image acquisition, interpretability of images captured, nature of the peripheral abnormality, and clinical utility in management decisions were recorded. Results: Eighty-two eyes from 72 patients were included. Patients were aged 59.4 ± 17.1 years (range, 8-87 years). During imaging, 4.4 series of images were obtained in 4.1 minutes, with 86.4% of the image series deemed to be diagnostic of the peripheral pathology on blinded image review. The most common pathologic findings were chorioretinal scars (18 eyes). In 31 (38%) eyes, these images were meaningful in supporting clinical decision-making with definitive findings. Diagnoses imaged included retinal detachment combined with retinoschisis, retinal hole with overlying vitreous traction and subretinal fluid, vitreous inflammation overlying a peripheral scar, Coats disease, and peripheral retinal traction in sickle cell retinopathy. Conclusions: Navigated UWF SS-OCT imaging was clinically practical and provided high-quality characterization of peripheral retinal lesions for all eyes. Images directly contributed to management plans, including laser, injection or surgical treatment, for a clinically meaningful set of patients (38%). Future studies are needed to further assess the value of this imaging modality and its role in diagnosing, monitoring, and treating peripheral lesions.

scholarly journals En face image-based classification of diabetic macular edema using swept source optical coherence tomography

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Atsushi Fujiwara ◽  
Yuki Kanzaki ◽  
Shuhei Kimura ◽  
Mio Hosokawa ◽  
Yusuke Shiode ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Macular Edema ◽  
Diabetic Macular Edema ◽  
Outer Nuclear Layer ◽  
Subretinal Fluid ◽  
Plexiform Layer ◽  
Optical Coherence ◽  
Fiber Layer ◽  
Swept Source ◽  
En Face

AbstractThis retrospective study was performed to classify diabetic macular edema (DME) based on the localization and area of the fluid and to investigate the relationship of the classification with visual acuity (VA). The fluid was visualized using en face optical coherence tomography (OCT) images constructed using swept-source OCT. A total of 128 eyes with DME were included. The retina was segmented into: Segment 1, mainly comprising the inner nuclear layer and outer plexiform layer, including Henle’s fiber layer; and Segment 2, mainly comprising the outer nuclear layer. DME was classified as: foveal cystoid space at Segment 1 and no fluid at Segment 2 (n = 24), parafoveal cystoid space at Segment 1 and no fluid at Segment 2 (n = 25), parafoveal cystoid space at Segment 1 and diffuse fluid at Segment 2 (n = 16), diffuse fluid at both segments (n = 37), and diffuse fluid at both segments with subretinal fluid (n = 26). Eyes with diffuse fluid at Segment 2 showed significantly poorer VA, higher ellipsoid zone disruption rates, and greater central subfield thickness than did those without fluid at Segment 2 (P < 0.001 for all). These results indicate the importance of the localization and area of the fluid for VA in DME.

scholarly journals Comparison of swept-source versus spectral-domain optical coherence tomography angiography for detection of macular neovascularization

2021 ◽  
Author(s):  
Anna Lentzsch ◽  
Laura Schöllhorn ◽  
Christel Schnorr ◽  
Robert Siggel ◽  
Sandra Liakopoulos
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Coherence Tomography Angiography ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Cross Sectional ◽  
Swept Source ◽  
En Face ◽  
Increased Sensitivity ◽  
Sensitivity Specificity ◽  
Subretinal Hyperreflective Material

Abstract Purpose To compare swept-source (SS) versus spectral-domain (SD) optical coherence tomography angiography (OCTA) for the detection of macular neovascularization (MNV). Methods In this prospective cohort study, 72 eyes of 54 patients with subretinal hyperreflective material (SHRM) and/or pigment epithelial detachment (PED) on OCT possibly corresponding to MNV in at least one eye were included. OCTA scans were acquired using two devices, the PLEX Elite 9000 SS-OCTA and the Spectralis SD-OCTA. Fluorescein angiography (FA) was used as reference. Two graders independently evaluated en face OCTA images using a preset slab as well as a manually modified slab, followed by a combination of en face and cross-sectional OCTA. Results Sensitivity (specificity) for the automated slabs was 51.7% (93.0%) for SS-OCTA versus 58.6% (95.3%) for SD-OCTA. Manual modification of segmentation increased sensitivity to 79.3% for SS-OCTA but not for SD-OCTA (58.6%). The combination of en face OCTA with cross-sectional OCTA reached highest sensitivity values (SS-OCTA: 82.8%, SD-OCTA: 86.2%), and lowest number of cases with discrepancies between SS-OCTA and SD-OCTA (4.2%). Fleiss kappa as measure of concordance between FA, SS-OCTA, and SD-OCTA was 0.56 for the automated slabs, 0.60 for the manual slabs, and 0.73 (good agreement) for the combination of en face OCTA with cross-sectional OCTA. Concordance to FA was moderate for the automated slabs and good for manual slabs and combination with cross-sectional OCTA of both devices. Conclusion Both devices reached comparable results regarding the detection of MNV on OCTA. Sensitivity for MNV detection and agreement between devices was best when evaluating a combination of en face and cross-sectional OCTA.

scholarly journals Choroidal vessel density in unilateral hyperopic amblyopia using en-face optical coherence tomography

2020 ◽  
Author(s):  
Syunsuke Araki ◽  
Atsushi Miki ◽  
Katsutoshi Goto ◽  
Tsutomu Yamashita ◽  
Tsuyoshi Yoneda ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Normal Control ◽  
Structural Changes ◽  
Vascular Density ◽  
Optical Coherence ◽  
Swept Source ◽  
3 Dimensional ◽  
Face Images ◽  
En Face ◽  
Normal Controls

Abstract Background Structural changes of the choroid, such as choroidal thickening, have been indicated in amblyopic eyes with hyperopic anisometropia as compared to fellow or healthy eyes. The purpose of the present study was to investigate choroidal vascular density (CVD) in children with unilateral hyperopic amblyopia.Methods This study included 88 eyes of 44 patients with unilateral amblyopia due to hyperopic anisometropia with or without strabismus and 29 eyes of 29 age-matched normal controls. The CVD of Haller's layer was quantified from en-face images constructed by 3-dimensional swept-source optical coherence tomography images flattened relative to Bruch's membrane. The analysis area was a 3×3-mm square of macula after magnification correction. Relationships between CVD and other parameters [best-corrected visual acuity (BCVA), refractive error and subfoveal choroidal thickness (SFCT)] were investigated, and CVDs were compared between amblyopic, fellow, and normal control eyes.Results Mean CVD was 59.11 ± 0.66% in amblyopic eyes, 59.23 ± 0.81% in fellow eyes, and 59.29 ± 0.74% in normal control eyes. CVD showed a significant positive relationship with SFCT (p=0.004), but no relationships with other parameters. No significant differences in CVD were evident among amblyopic, fellow, and normal control eyes after adjusting for SFCT (p=0.502).Conclusions CVD was unrelated to BCVA, and CVD did not differ significantly among amblyopic, fellow and normal control eyes. These results suggest that the local CVD of Haller's layer is unaffected in unilateral hyperopic amblyopic eyes.

Η σημασία της ισχαιμίας της ωχράς στις φλεβικές αποφράξεις αμφιβληστροειδούς

2018 ◽  
Author(s):  
Κωνσταντίνα Γιαννούλη
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Coherence ◽  
En Face Oct ◽  
En Face

Να μελετηθεί η στιβάδα των φωτοϋποδοχέων, σε οφθαλμούς με κλαδική απόφραξη φλέβας αμφιβληστροειδούς και ισχαιμία ωχράς, χρησιμοποιώντας μία μέθοδο en face optical coherence tomography (OCT) απεικόνισης της ελλειψοειδούς ζώνης.Μέθοδος: Προσαρμοσμένα OCT scans ωχράς, από 9 ασθενείς (10 οφθαλμοί) με κλαδική απόφραξη φλέβας αμφιβληστροειδούς και ισχαιμία ωχράς , εξήχθησαν και επεξεργάστηκαν (αφαίρεση σκιών προερχόμενων από αγγεία και κυστικούς χώρους, διαχωρισμός στιβάδων και ευθειασμός στο επίπεδο του μελάγχρου επιθηλίου). Η ελλειψοειδής ζώνη διαχωρίστηκε, ευθειάστηκε και χρησιμοποιήθηκε για τη δημιουργία της en face OCT εικόνας. Έγινε σύγκριση μεταξύ των υποανακλαστικών περιοχών απώλειας φωτοϋποδοχέων και των ισχαιμικών περιοχών, όπως οι τελευταίες καταγράφηκαν στις πρώιμες φάσεις της φλουοροαγγειογραφίας.Αποτελέσματα: Οι περιοχές απώλειας του τριχοειδικού δικτύου (στη φλουοραγγειογραφία), παρουσίασαν σαφή συσχέτιση με τις περιοχές διαταραχής της ελλειψοειδούς ζώνης (στην en face OCT απεικόνιση). Οι περιοχές διαταραχής της ελλειψοειδούς ζώνης είχαν ανομοιόμορφη εικόνα, και σαφή ή ασαφή όρια, ανάλογα με τη βαρύτητα της βλάβης.Συμπέρασμα: Η en face OCT απεικόνιση της ελλειψοειδούς ζώνης ανέδειξε μία σαφή συσχέτιση μεταξύ της απώλειας του τριχοειδικού δικτύου και των διαταραχών της ελλειψοειδούς ζώνης σε οφθαλμούς με κλαδική απόφραξη φλέβας αμφιβληστροειδούς. Το εν τω βάθει τριχοειδικό δίκτυο προφανώς συμβάλλει σημαντικά στις μεταβολικές ανάγκες του έξω αμφιβληστροειδούς και, κατά συνέπεια, ισχαιμία στο επίπεδο του εν τω βάθει τριχοειδικού δικτύου έχει σοβαρό αντίκτυπο στην ακεραιότητα των φωτοϋποδοχέων.

Topographic Analysis of Short Posterior Ciliary Arteries Using Wide-Field Swept-Source En-Face Optical Coherence Tomography

2021 ◽  
Author(s):  
Raphael Lejoyeux ◽  
Raphael Atia ◽  
Kiran Vupparaboina ◽  
Mohamed Ibrahim ◽  
Jose-Alain Sahel ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Posterior Pole ◽  
Wide Field ◽  
Temporal Part ◽  
Optical Coherence ◽  
Cross Sectional ◽  
Swept Source ◽  
Topographic Analysis ◽  
En Face ◽  
Ciliary Arteries

Abstract Purpose: To study the topographic distribution of the short posterior ciliary arteries (SPCA) entry sites into the choroid in normal eyes using structural en-face swept source optical coherence tomography (SS-OCT). Methods: Retrospective analysis of SS-OCT scans (wide-field structural SS-OCT 12x12mm) of 13 healthy subjects was performed. Cross-sectional swept-source OCT scans derived from a volume scan were represented as en-face image display following the Choroid-Scleral Interface to obtain en-face OCT. SPCAs in their last scleral location before choroidal entrance were identified manually, counted and localized by two masked observers. Correlations between two masked observers were analyzed using inter- and intra- class correlation. Results: Accuracy for the choroidal inner and outer border segmentation was 95-99%. Eighteen eyes from 13 normal subjects were included for SPCA analysis. The mean number of arteries was 13.8±3.5 per eye. Thirty-six percent were in the center of the posterior pole image; however, 21% were in the temporal part of the posterior pole. Median accuracy of the detection is 0.94. The correlation between the two observers was fair (0.54).Conclusion: Our algorithm allows visualization of the SPCA at the posterior pole of the eye using wide-field en-face SS-OCT. It can also help the clinicians to study the SPCAs in numerous ocular diseases, particularly its relationship with focal choroidal diseases.

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