scholarly journals The Relevance of Nasal Provocation Testing in Children with Nonallergic Rhinitis

2016 ◽  
Vol 170 (2) ◽  
pp. 115-121 ◽  
Author(s):  
Handan Duman ◽  
Ilknur Bostanci ◽  
Serap Ozmen ◽  
Mahmut Dogru
Keyword(s):  
Nonallergic Rhinitis ◽  
Nasal Provocation ◽  
Provocation Testing ◽  
Nasal Provocation Testing

The Importance of Nasal Provocation Testing in the Diagnosis of Dermatophagoides pteronyssinus-Induced Allergic Rhinitis

2021 ◽  
pp. 194589242110379
Author(s):  
Hao Xiao ◽  
Qiaoru Jia ◽  
Hongting Zhang ◽  
Li Zhang ◽  
Guo Liu ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Immunoglobulin E ◽  
Area Under The Curve ◽  
Roc Curves ◽  
Dermatophagoides Pteronyssinus ◽  
Allergen Specific Immunotherapy ◽  
Prick Test ◽  
Nasal Provocation ◽  
Provocation Testing ◽  
Nasal Provocation Testing

Background Allergen identification is the first step for allergen-specific immunotherapy (AIT) of allergic rhinitis (AR). Currently, the diagnosis of AR is based mainly on the positive results of the skin prick test (SPT) and/or serum specific immunoglobulin E (sIgE) measurement. However, the results of these two tests may not always directly correlate with AR. Objective To investigate the importance of nasal provocation testing (NPT) in the diagnosis of Dermatophagoides pteronyssinus (Der p)-induced AR. Methods Rhinitis patients willing to undergo AIT (n = 171) were enrolled. The correlations of Der p SPT, sIgE, NPT, and clinical symptom severity were assessed. Results NPT-positive responses were more common in patients with higher SPT and sIgE levels. The optimal cut-off value for a NPT-positive response for SPT was 5.5 mm and for sIgE was 2.77 kUA/L, based on the respective receiver operating characteristic (ROC) curves. The area under the curve (AUC) of the ROCs was 0.814 (SPT only) and 0.794 (sIgE only) and increased to 0.828 with the combination of SPT and sIgE. The Der p-NPT concentration was inversely correlated with SPT and sIgE levels ( r = −0.477, P < .001, and r = −0.461, P < .001, respectively), but none was correlated with the total nasal symptom score. Conclusion For patients who are willing to receive Der p AIT, NPT is a useful and safe test to confirm diagnosis prior to treatment initiation, especially in patients with lower levels of Der p SPT (< 5.5 mm) or sIgE (< 2.77 kUA/L).

Comparison of optical rhinometry to acoustic rhinometry using nasal provocation testing with Dermatophagoides farinae

2010 ◽  
Vol 143 (2) ◽  
pp. 290-293 ◽  
Author(s):  
Esther J. Cheung ◽  
Martin J. Citardi ◽  
Samer Fakhri ◽  
Jordan Cain ◽  
Pete S. Batra ◽  
...  
Keyword(s):  
Acoustic Rhinometry ◽  
Dermatophagoides Farinae ◽  
Nasal Provocation ◽  
Provocation Testing ◽  
Nasal Provocation Testing ◽  
Optical Rhinometry

Nasal Provocation Testing

2009 ◽  
pp. 1281-1294 ◽  
Author(s):  
Alkis Togias ◽  
Jonathan Correnand ◽  
Martin Wagenmann
Keyword(s):  
Nasal Provocation ◽  
Provocation Testing ◽  
Nasal Provocation Testing

Nasal lavage concentrations of free hemoglobin as a marker of microepistaxis during nasal provocation testing*

Allergy ◽  
2002 ◽  
Vol 57 (4) ◽  
pp. 329-335 ◽  
Author(s):  
Y.-J. Park ◽  
M. S. Repka-Ramirez ◽  
K. Naranch ◽  
A. Velarde ◽  
D. Clauw ◽  
...  
Keyword(s):  
Nasal Lavage ◽  
Free Hemoglobin ◽  
Nasal Provocation ◽  
Provocation Testing ◽  
Nasal Provocation Testing
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