scholarly journals Screening for Language Disorders in Stroke: German Validation of the Language Screening Test (LAST)

2016 ◽  
Vol 6 (1) ◽  
pp. 27-31 ◽  
Author(s):  
M. Koenig-Bruhin ◽  
T. Vanbellingen ◽  
R. Schumacher ◽  
T. Pflugshaupt ◽  
J.M. Annoni ◽  
...  
Keyword(s):  
External Validity ◽  
Screening Test ◽  
Intraclass Correlation ◽  
Internal Validity ◽  
Short Version ◽  
Language Therapy ◽  
Language Deficit ◽  
Token Test ◽  
Language Screening ◽  
High Intraclass Correlation Coefficient

Background: Screening of aphasia in acute stroke is crucial for directing patients to early language therapy. The Language Screening Test (LAST), originally developed in French, is a validated language screening test that allows detection of a language deficit within a few minutes. The aim of the present study was to develop and validate two parallel German versions of the LAST. Methods: The LAST includes subtests for naming, repetition, automatic speech, and comprehension. For the translation into German, task constructs and psycholinguistic criteria for item selection were identical to the French LAST. A cohort of 101 stroke patients were tested, all of whom were native German speakers. Validation of the LAST was based on (1) analysis of equivalence of the German versions, which was established by administering both versions successively in a subset of patients, (2) internal validity by means of internal consistency analysis, and (3) external validity by comparison with the short version of the Token Test in another subset of patients. Results: The two German versions were equivalent as demonstrated by a high intraclass correlation coefficient of 0.91. Furthermore, an acceptable internal structure of the LAST was found (Cronbach's α = 0.74). A highly significant correlation (r = 0.74, p < 0.0001) between the LAST and the short version of the Token Test indicated good external validity of the scale. Conclusion: The German version of the LAST, available in two parallel versions, is a new and valid language screening test in stroke.

scholarly journals Validity and Reliability of the Persian Version of Language Screening Test (LAST) for Patients in the Acute Phase of Stroke

2020 ◽  
Vol 3 (1) ◽  
pp. 91-100
Author(s):  
Seyyede Zohreh Mousavi ◽  
◽  
Reyhaneh Jafari ◽  
Saman Maroufizadeh3 ◽  
Mohammad Moez Shahramnia ◽  
...  
Keyword(s):  
Correlation Coefficient ◽  
Acute Phase ◽  
Screening Test ◽  
Intraclass Correlation ◽  
Chronic Phase ◽  
Weighted Kappa ◽  
Screening Tests ◽  
Rater Reliability ◽  
Persian Version ◽  
Language Screening

Background & Objectives: Aphasia is one of the most common consequences of a stroke; thus, screening tests for early diagnosis of the problem are necessary when dealing with aphasia patients. One of these screening tests is the Language Screening Test (LAST). The purpose of this study was to translate, validate, and utilize this test in the Persian language for patients after stroke. Methods: The original version of LAST was translated into Persian, and then administrated on 100 patients in the acute phase by two examiners at the patient’s bedside in order to check the inter-rater reliability. To assess the agreement between the two forms (a and b) of the LAST, Concordance Correlation Coefficient (CCC), weighted Kappa, and Intraclass Correlation Coefficient (ICC) were used. Also, the Persian version of LAST and the Western Aphasia Battery (WAB) were performed at the chronic phase with two independent examiners with blind scoring. Results: Inter-rater reliability between Rater 1 and Rater 2 on LAST-a and LAST-b score were very good for both phases. The CCC for LAST-a and LAST-b, respectively, were 0.874 and 0.865 for the acute phase and 0.923 and 0.927 for the chronic phase. The weighted Kappa for LAST-a and LAST-b, respectively, were 0.750 and 0.740 for the acute phase, and 0.822 and 0.846 for the chronic phase. Conclusion: The obtained results showed that LAST is a very simple, fast, and valid test and can be used as a reliable tool in stroke patients. Lack of cultural and language dependency are the advantages of using this test.

scholarly journals A novel preference-informed complementary trial (PICT) design for clinical trial research influenced by strong patient preferences

Trials ◽  
2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Samina Ali ◽  
◽  
Gareth Hopkin ◽  
Naveen Poonai ◽  
Lawrence Richer ◽  
...  
Keyword(s):  
External Validity ◽  
Treatment Options ◽  
Internal Validity ◽  
Clinical Effectiveness ◽  
Drop Out ◽  
Innovative Design ◽  
Clinical Trial Research ◽  
Research Questions ◽  
Internal And External Validity ◽  
Treatment Population

Abstract Background Patients and their families often have preferences for medical care that relate to wider considerations beyond the clinical effectiveness of the proposed interventions. Traditionally, these preferences have not been adequately considered in research. Research questions where patients and families have strong preferences may not be appropriate for traditional randomized controlled trials (RCTs) due to threats to internal and external validity, as there may be high levels of drop-out and non-adherence or recruitment of a sample that is not representative of the treatment population. Several preference-informed designs have been developed to address problems with traditional RCTs, but these designs have their own limitations and may not be suitable for many research questions where strong preferences and opinions are present. Methods In this paper, we propose a novel and innovative preference-informed complementary trial (PICT) design which addresses key weaknesses with both traditional RCTs and available preference-informed designs. In the PICT design, complementary trials would be operated within a single study, and patients and/or families would be given the opportunity to choose between a trial with all treatment options available and a trial with treatment options that exclude the option which is subject to strong preferences. This approach would allow those with strong preferences to take part in research and would improve external validity through recruiting more representative populations and internal validity. Here we discuss the strengths and limitations of the PICT design and considerations for analysis and present a motivating example for the design based on the use of opioids for pain management for children with musculoskeletal injuries. Conclusions PICTs provide a novel and innovative design for clinical trials with more than two arms, which can address problems with existing preference-informed trial designs and enhance the ability of researchers to reflect shared decision-making in research as well as improving the validity of trials of topics with strong preferences.

Investigating the Youth Physical Activity Promotion Model: Internal Structure and External Validity Evidence for a Potential Measurement Model

2007 ◽  
Vol 19 (4) ◽  
pp. 420-435 ◽  
Author(s):  
David A. Rowe ◽  
Thomas D. Raedeke ◽  
Lenny D. Wiersma ◽  
Matthew T. Mahar
Keyword(s):  
Physical Activity ◽  
External Validity ◽  
Internal Validity ◽  
Physical Activity Promotion ◽  
Measurement Model ◽  
Measurement Properties ◽  
Validity Evidence ◽  
Potential Measurement ◽  
Activity Promotion ◽  
Youth Physical Activity

The purpose of the study was to investigate the measurement properties of questionnaires associated with the Youth Physical Activity Promotion (YPAP) model. Data were collected from 296 children in Grades 5–8 using several existing questionnaires corresponding to YPAP model components, a physical activity questionnaire, and 6 consecutive days of pedometer data. Internal validity of the questionnaires was tested using confirmatory factor analyses, and external validity was investigated via correlations with physical activity and body composition. Initial model fit of the questionnaires ranged from poor to very good. After item removal, all scales demonstrated good fit. Correlations with percentage body fat and objectively measured physical activity were low but in the theoretically predicted direction. The current study provides good internal validity evidence and acceptable external validity evidence for a brief set of questionnaire items to investigate the theoretical basis for the YPAP model.

scholarly journals Toward Experimental International Business

2015 ◽  
Vol 22 (4) ◽  
pp. 530-544 ◽  
Author(s):  
Arjen van Witteloostuijn
Keyword(s):  
International Business ◽  
External Validity ◽  
Design Methodology ◽  
Internal Validity ◽  
Cross Cultural ◽  
Web Based ◽  
Content Type ◽  
Experimental Laboratory ◽  
Experimental Management ◽  
Missed Opportunity

Purpose – The purpose of this paper is to argue that the time is ripe to establish a powerful tradition in Experimental International Business (IB). Probably due to what the Arjen van Witteloostuijn refers to as the external validity myth, experimental laboratory designs are underutilized in IB, which implies that the internal validity miracle of randomized experimentation goes largely unnoticed in this domain of the broader management discipline. Design/methodology/approach – In the following pages, the author explains why the author believes this implies a missed opportunity, providing arguments and examples along the way. Findings – Although an Experimental Management tradition has never really gained momentum, to the author, the lab experimental design has a very bright future in IB (and management at large). To facilitate the development of an Experimental IB tradition, initiating web-based tools would be highly instrumental. This will not only boost further progress in IB research, but will also increase the effectiveness and playfulness of IB teaching. Originality/value – Given the high potential of an Experimental IB, the Cross-Cultural and Strategic Management journal will offer a platform for such exciting and intriguing laboratory work, cumulatively contributing to the establishment of an Experimental IB tradition.

Validity and reliability of a wearable-controlled serious game and goniometer for telemonitoring of wrist fracture rehabilitation

2021 ◽  
Author(s):  
Henriëtte A. W. Meijer ◽  
Maurits Graafland ◽  
Miryam C. Obdeijn ◽  
Marlies P. Schijven ◽  
J. Carel Goslings
Keyword(s):  
Range Of Motion ◽  
Intraclass Correlation ◽  
Internal Validity ◽  
Wrist Fracture ◽  
Serious Game ◽  
Reference Standard ◽  
Validity And Reliability ◽  
Good Reliability ◽  
Rater Reliability ◽  
Flexion Extension

Abstract Purpose To determine the validity of wrist range of motion (ROM) measurements by the wearable-controlled ReValidate! wrist-rehabilitation game, which simultaneously acts as a digital goniometer. Furthermore, to establish the reliability of the game by contrasting ROM measurements to those found by medical experts using a universal goniometer. Methods As the universal goniometer is considered the reference standard, inter-rater reliability between surgeons was first determined. Internal validity of the game ROM measurements was determined in a test–retest setting with healthy volunteers. The reliability of the game was tested in 34 patients with a restricted range of motion, in whom the ROM was measured by experts as well as digitally. Intraclass-correlation coefficients (ICCs) were determined and outcomes were analyzed using Bland–Altman plots. Results Inter-rater reliability between experts using a universal goniometer was poor, with ICCs of 0.002, 0.160 and 0.520. Internal validity testing of the game found ICCs of − 0.693, 0.376 and 0.863, thus ranging from poor to good. Reliability testing of the game compared to medical expert measurements, found that mean differences were small for the flexion–extension arc and the radial deviation-ulnar deviation arc. Conclusion The ReValidate! game is a reliable home-monitoring device digitally measuring ROM in the wrist. Interestingly, the test–retest reliability of the serious game was found to be considerably higher than the inter-rater reliability of the reference standard, being healthcare professionals using a universal goniometer. Trial registration number (internal hospital registration only) MEC-AMC W17_003 #17.015.

scholarly journals Designing Research With Qualitative Comparative Analysis (QCA): Approaches, Challenges, and Tools

2017 ◽  
Vol 49 (2) ◽  
pp. 356-386 ◽  
Author(s):  
Eva Thomann ◽  
Martino Maggetti
Keyword(s):  
Comparative Analysis ◽  
External Validity ◽  
Qualitative Comparative Analysis ◽  
Internal Validity ◽  
Specific Research ◽  
Extant Literature ◽  
Specific Mode ◽  
Research Context ◽  
Trade Offs ◽  
Conducting Research

Recent years have witnessed a host of innovations for conducting research with qualitative comparative analysis (QCA). Concurrently, important issues surrounding its uses have been highlighted. In this article, we seek to help users design QCA studies. We argue that establishing inference with QCA involves three intertwined design components: first, clarifying the question of external validity; second, ensuring internal validity; and third, explicitly adopting a specific mode of reasoning. We identify several emerging approaches to QCA rather than just one. Some approaches emphasize case knowledge, while others are condition oriented. Approaches emphasize either substantively interpretable or redundancy-free explanations, and some designs apply an inductive/explorative mode of reasoning, while others integrate deductive elements. Based on extant literature, we discuss issues surrounding inference with QCA and the tools available under different approaches to address these issues. We specify trade-offs and the importance of doing justice to the nature and goals of QCA in a specific research context.

scholarly journals High Fidelity Microsurgical Simulation: The Thiel Model and Evaluation Instrument

2018 ◽  
Vol 27 (2) ◽  
pp. 118-124 ◽  
Author(s):  
Andrei Odobescu ◽  
Isak Goodwin ◽  
Djamal Berbiche ◽  
Joseph BouMerhi ◽  
Patrick G. Harris ◽  
...  
Keyword(s):  
External Validity ◽  
Internal Validity ◽  
High Fidelity ◽  
Evaluation Instrument ◽  
Intra Class Correlation ◽  
Validity Measures ◽  
The Difference ◽  
Fidelity Model ◽  
Junior Residents ◽  
Internal And External Validity

Background: The Thiel embalmment method has recently been used in a number of medical simulation fields. The authors investigate the use of Thiel vessels as a high fidelity model for microvascular simulation and propose a new checklist-based evaluation instrument for microsurgical training. Methods: Thirteen residents and 2 attending microsurgeons performed video recorded microvascular anastomoses on Thiel embalmed arteries that were evaluated using a new evaluation instrument (Microvascular Evaluation Scale) by 4 fellowship trained microsurgeons. The internal validity was assessed using the Cronbach coefficient. The external validity was verified using regression models. Results: The reliability assessment revealed an excellent intra-class correlation of 0.89. When comparing scores obtained by participants from different levels of training, attending surgeons and senior residents (Post Graduate Year [PGY] 4-5) scored significantly better than junior residents (PGY 1-3). The difference between senior residents and attending surgeons was not significant. When considering microsurgical experience, the differences were significant between the advanced group and the minimal and moderate experience groups. The differences between minimal and moderate experience groups were not significant. Based on the data obtained, a score of 8 would translate into a level of microsurgical competence appropriate for clinical microsurgery. Conclusions: Thiel cadaveric vessels are a high fidelity model for microsurgical simulation. Excellent internal and external validity measures were obtained using the Microvascular Evaluation Scale (MVES).

External Validity: The Next Step for Systematic Reviews?

2016 ◽  
Vol 41 (4) ◽  
pp. 283-325 ◽  
Author(s):  
Sarah A. Avellar ◽  
Jaime Thomas ◽  
Rebecca Kleinman ◽  
Emily Sama-Miller ◽  
Sara E. Woodruff ◽  
...  
Keyword(s):  
Systematic Review ◽  
Systematic Reviews ◽  
External Validity ◽  
Home Visiting ◽  
Evaluation Research ◽  
Internal Validity ◽  
Reporting Guidelines ◽  
Sample Characteristics ◽  
Statistical Representativeness

Background: Systematic reviews—which identify, assess, and summarize existing research—are usually designed to determine whether research shows that an intervention has evidence of effectiveness, rather than whether an intervention will work under different circumstances. The reviews typically focus on the internal validity of the research and do not consistently incorporate information on external validity into their conclusions. Objectives: In this article, we focus on how systematic reviews address external validity. Methods: We conducted a brief scan of 19 systematic reviews and a more in-depth examination of information presented in a systematic review of home visiting research. Results: We found that many reviews do not provide information on generalizability, such as statistical representativeness, but focus on factors likely to increase heterogeneity (e.g., numbers of studies or settings) and report on context. The latter may help users decide whether the research characteristics—such as sample demographics or settings—are similar to their own. However, we found that differences in reporting, such as which variables are included and how they are measured, make it difficult to summarize across studies or make basic determinations of sample characteristics, such as whether the majority of a sample was unemployed or married. Conclusion: Evaluation research and systematic reviews would benefit from reporting guidelines for external validity to ensure that key information is reported across studies.

Language Screening Test--Version Québécoise

2015 ◽  
Author(s):  
J. Bourgeois-Marcotte ◽  
C. Flamand-Roze ◽  
C. Denier ◽  
L. Monetta
Keyword(s):  
Screening Test ◽  
Test Version ◽  
Language Screening
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