scholarly journals Langerhans Cell Histiocytosis of the Rib in an Adult: A Case Report

2016 ◽  
Vol 9 (1) ◽  
pp. 83-88 ◽  
Author(s):  
Sung Hyun Kim ◽  
Moon Young Choi
Keyword(s):  
Back Pain ◽  
Case Report ◽  
Local Recurrence ◽  
Bone Tumor ◽  
Langerhans Cell Histiocytosis ◽  
Osteolytic Lesion ◽  
Langerhans Cell ◽  
Pathologic Finding ◽  
Single System

Single-site, single-system Langerhans cell histiocytosis (LCH) of the rib is one of the rarest causes of bone tumor in adults. Herein, we report a case of a healthy 35-year-old male who presented with upper back pain that was attributed to a solitary osteolytic lesion at the posterolateral aspect of his sixth rib. For diagnostic confirmation and treatment, partial resection of the sixth rib was performed and pathologic finding was consistent with LCH. At the final follow-up after 2 years, no local recurrence or metastasis was observed.

scholarly journals Langerhans Cell Histiocytosis of the Clavicle in an Adult: A Case Report and Review of the Literature

2015 ◽  
Vol 8 (3) ◽  
pp. 426-431 ◽  
Author(s):  
Toru Udaka ◽  
Michiro Susa ◽  
Kazutaka Kikuta ◽  
Kazumasa Nishimoto ◽  
Keisuke Horiuchi ◽  
...  
Keyword(s):  
Case Report ◽  
Local Recurrence ◽  
Langerhans Cell Histiocytosis ◽  
Langerhans Cell ◽  
Review Of The Literature

Langerhans cell histiocytosis (LCH) usually occurs in children under the age of 10 years with a predilection for the skull, spine, rib and humerus. Solitary LCH occurring in an adult clavicle is uncommon with limited reports to date. The lesion in our patient was curetted with the intent to make a diagnosis, which subsequently lead to the remission of the symptom and the disease. At the final follow-up after 1 year, no local recurrence or metastasis is observed.

PP – 10-YEAR FOLLOW- UP OF A SINGLE-SYSTEM LANGERHANS CELL HISTIOCYTOSIS - MULTIFOCAL BONE INVOLVEMENT

2017 ◽  
Vol 123 (2) ◽  
pp. e66
Author(s):  
RENATA MENDONÇA MORAES ◽  
JOYCE GIMENEZ MENON ◽  
JULIANA ROCHA VERRONE ◽  
JOSÉ DIVALDO PRADO ◽  
FERNANDO AUGUSTO SOARES ◽  
...  
Keyword(s):  
Langerhans Cell Histiocytosis ◽  
Langerhans Cell ◽  
Bone Involvement ◽  
Single System

scholarly journals Nonbacterial Osteitis of the Clavicle: Longitudinal Imaging Series from Initial Diagnosis to Clinical Improvement

2015 ◽  
Vol 2015 ◽  
pp. 1-4
Author(s):  
E. Roos ◽  
M. Maas ◽  
S. J. M. Breugem ◽  
G. R. Schaap ◽  
J. A. M. Bramer
Keyword(s):  
Case Report ◽  
Clinical Improvement ◽  
Langerhans Cell Histiocytosis ◽  
Autoinflammatory Disease ◽  
Langerhans Cell ◽  
Differential Diagnoses ◽  
Longitudinal Imaging ◽  
The Right ◽  
Established Treatment

Nonbacterial osteitis is a rare autoinflammatory disease. Often it is mistaken for a tumor or osteomyelitis. We present a case of a twelve-year-old girl referred to our hospital because of a lesion of the right clavicle. The differential diagnoses were sarcoma, osteitis, and Langerhans cell histiocytosis. After biopsy the diagnosis nonbacterial osteitis (NBO) was established. Treatment of choice is a nonsteroidal anti-inflammatory drug. This case report gives a complete follow-up of the disease, showing the pitfalls of the diagnosis.

scholarly journals Oral Langerhans cell histiocytosis: case report with follow-up of ten years

2014 ◽  
Vol 80 (4) ◽  
pp. 366-367 ◽  
Author(s):  
Emeline das Neves de Araújo Lima ◽  
Eliakim Medeiros Alves de Araújo ◽  
Patrícia Teixeira de Oliveira ◽  
Ana Miryam Costa de Medeiros
Keyword(s):  
Case Report ◽  
Langerhans Cell Histiocytosis ◽  
Langerhans Cell

scholarly journals Clinical characteristics and survival of children with Langerhans cell hystiocytosis

2008 ◽  
Vol 136 (9-10) ◽  
pp. 514-518
Author(s):  
Nada Krstovski ◽  
Dragana Janic ◽  
Lidija Dokmanovic ◽  
Radivoj Brdar
Keyword(s):  
Langerhans Cell Histiocytosis ◽  
Clinical Characteristics ◽  
Clinical Presentation ◽  
Clinical Course ◽  
Langerhans Cell ◽  
Single System ◽  
Multisystem Disease ◽  
System Disease ◽  
The Central Nervous System

INTRODUCTION Langerhans cell histiocytosis is a rare disease in children, initial presentation is variable, clinical course, prognosis and survival are mostly unpredictable. OBJECTIVE To summarise clinical characteristics and treatment results in children with Langerhans cell histiocytosis. METHOD Retrospectively there were analyzed patients with LCH diagnosed and treated at Hematology Department of University Children's Hospital in Belgrade from 1990 to 2006. Clinical presentation, therapy and survival according to Kaplan-Meier's statistical test was analysed. RESULTS 30 patients were treated, aged from 4 months to 14 years, mean 3.9 years, median 2.3 years, 18 (60%) males, 12 (40%) females. A single system disease was diagnosed in 16 (53%) patients, of whom 6 patients with multifocal bone disease. All patients were in complete remission averagely following162 and 82 months respectively. Multisystem disease was found in 14 (47%) patients. The lymph nodes and skin were more frequently involved organs than the central nervous system (diabetes insipidus), lung, liver and spleen. The number of involved organs ranged from 2 to 8, mean 4.2. Four patients died due to disease progression 3, 16, 36 and 66 months after diagnosis. Nine patents with multisystem disease were in remission with 117 months of follow-up. One patient was lost on follow-up. CONCLUSION The clinical course of patients with a single system disease is usually benign while a multisystem disease has to be aggressively treated with precise initial evaluation and staging before therapy.

scholarly journals Rare Case of Adult Langerhans Cell Histiocytosis: A Case Report

2019 ◽  
Vol 13 (1) ◽  
pp. 17
Author(s):  
Dinny Gustina Prihadi ◽  
Agung Firmansyah Sumantri ◽  
Hasyarati Agustina ◽  
Indra Wijaya
Keyword(s):  
Case Report ◽  
Langerhans Cell Histiocytosis ◽  
Rare Case ◽  
Malignant Tumors ◽  
Corticosteroid Injection ◽  
Langerhans Cell ◽  
Intralesional Corticosteroid ◽  
Adult Male Patient

Background: Langerhans Cell Histiocytosis (LCH) is a disease characterized by proliferation and infiltration of histiocytes in various organs that is caused by local or systemic effects. LCH could affect bones, lungs, central nervous system, liver, thymus, skin, and lymph nodes. The diagnosis of LCH is difficult to enforce and rarely found in adults, namely 1-2 cases per million per year.Case Presentation: In Indonesia, there were very few cases of LCH in adults, one of which was found in women aged 56 years. LCH does not yet have standard treatments. The treatment is given based on location and severity, including intralesional corticosteroid injection, radiotherapy, surgical or excision curettage, and chemotherapy. Prednisone and vinblastine chemotherapy was one of chemotherapy that is given to LCH patients. Prognosis of LCH consists of various factors, one of which is the number of organs involved. This is a case report of LCH in an adult male patient with skin involvement who received chemotherapy for 6 weeks and experienced improvement.Conclusions: LCH is not only a disease of children; it is also reported in an adult. The prognosis is related to the number of organ involved and involvement of the risk organ. LCH can recur easily and accompany malignant tumors, so follow-up and long-term observations are still needed to be done.

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