Optical Coherence Tomography Angiography of Type 1 Neovascularization in Age-Related Macular Degeneration

2016 ◽  
pp. 45-51 ◽  
Author(s):  
Nicholas A. Iafe ◽  
Nopasak Phasukkijwatana ◽  
David Sarraf
Keyword(s):  
Optical Coherence Tomography ◽  
Macular Degeneration ◽  
Optical Coherence Tomography Angiography ◽  
Age Related Macular Degeneration ◽  
Optical Coherence ◽  
Age Related

Optical Coherence Tomography Angiography of Type 1 Neovascularization in Age-Related Macular Degeneration

2015 ◽  
Vol 160 (4) ◽  
pp. 739-748.e2 ◽  
Author(s):  
Laura Kuehlewein ◽  
Mayank Bansal ◽  
Tamara L. Lenis ◽  
Nicholas A. Iafe ◽  
SriniVas R. Sadda ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Macular Degeneration ◽  
Optical Coherence Tomography Angiography ◽  
Age Related Macular Degeneration ◽  
Optical Coherence ◽  
Age Related

scholarly journals Comparison of optical coherence tomography angiography features in type 1 versus type 2 choroidal neovascular membranes secondary to age-related macular degeneration

2021 ◽  
Vol 10 (2) ◽  
pp. 25-31
Author(s):  
Yasin Sakir Goker ◽  
Gokhan Demir
Keyword(s):  
Optical Coherence Tomography ◽  
Macular Degeneration ◽  
Optical Coherence Tomography Angiography ◽  
Age Related Macular Degeneration ◽  
Optical Coherence ◽  
Dead Tree ◽  
Flow Area ◽  
Age Related

Background: Optical coherence tomography angiography (OCTA) is an advanced imaging modality that provides high resolution images at the level of different retinal layers. This study aime to evaluate choroidal neovascular membranes (CNVMs) secondary to age-related macular degeneration (AMD) quantitatively and qualitatively, according to their classification, morphological features, and flow areas, using OCTA. Methods: In this descriptive, comparative, cross-sectional study, CNVMs were divided into 2 groups according to their classification as type 1 or type 2 neovascularization. Mixed CNVMs were excluded from the study. The size (mm2) and the flow area (mm2) of the CNVMs were calculated via OCTA and the presence of the perivascular halo and loop anastomoses were analyzed. The morphological appearance of the CNVMs were classified as: medusa, sea-fan, lacy-wheel, glomerular, dead tree, and mature vascular networks. Results: Of the 85 eyes assessed for eligibility, 45 eyes of 34 individuals with CNVM were enrolled in this retrospective study. Twenty-eight eyes had type 1 and 17 eyes had type 2 CNVMs. The mean size and flow area were greater in type 1 than in type 2 CNVMs (mean ± standard deviation [SD], 6.69 ± 4.54 and 3.61 ± 3.56 mm2 versus 3.04 ± 1.98 and 1.77 ± 1.62 mm2; P = 0.044 and 0.046, respectively). Among the 22 eyes with type 1 CNVMs and the 9 eyes with type 2 CNVMs, 31 eyes had exudative membranes. Among the eyes with exudative CNVMs, 22 eyes had a perivascular halo and 22 eyes had loop anastomoses; this was significantly more than in the non-exudative eyes (P = 0.042 and 0.041, respectively). The lacy-wheel (38.7%) and dead tree (71.4%) patterns were the most frequent morphological appearance of the CNVMs in the exudative and non-exudative membranes, respectively. Conclusions: OCTA provides objective documantation about CNVMs. A perivascular dark halo around CNVMs could be a criterion to define exudative membranes activity. How to cite this article: Goker YS, Demir G. Comparison of optical coherence tomography angiography features in type 1 versus type 2 choroidal neovascular membranes secondary to age-related macular degeneration. Med Hypothesis Discov Innov Ophthalmol. 2021 Summer; 10(2): 25-31. https://doi.org/10.51329/mehdiophthal1423

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