scholarly journals Some Important Milestones in the Field of Blood Clotting

2015 ◽  
Vol 8 (1) ◽  
pp. 23-29 ◽  
Author(s):  
Russell F. Doolittle

Several different kinds of ‘milestone' in the field of blood coagulation are described from the middle decades of the 20th century. Although viewed from the standpoint of clotting per se, attention is also given to implications for innate immunity. The first milestone considered is the protracted saga of clotting dependence on vitamin K, an adventure that spanned more than five decades beginning in the 1920s. The second has to do with the discovery of a half-dozen ‘new' clotting factors during the period immediately following World War II. A third pursues a narrower focus and examines the once mysterious transformation of fibrinogen into fibrin. Finally, the clinical treatment of classical hemophilia had a remarkable turning point in the 1960s as the result of simple but sensible measures.

1968 ◽  
Vol 20 (01/02) ◽  
pp. 078-087 ◽  
Author(s):  
H. C Hemker ◽  
A. D Muller

SummaryPIVKA, the circulating anticoagulant protein found in vitamin K deficiency can, on kinetical grounds, be recognized as an analogue of factor X. The existence of analogues of other vitamin K-dependent clotting factors cannot be ruled out, but need not be assumed to explain the experimental results.


2017 ◽  
Vol 2 (3) ◽  

For almost 20 years after the end of World War II, many Japanese women were challenged by a dark secondary hyper pigmentation on their faces. The causation of this condition was unknown and incurable at the time. However this symptom became curable after a number of new cosmetic allergens were discovered through patch tests and as an aftermath, various cosmetics and soaps that eliminated all these allergens were put into production to be used exclusively for these patients. An international research project conducted by seven countries was set out to find out the new allergens and discover non-allergic cosmetic materials. Due to these efforts, two disastrous cosmetic primary sensitizers were banned and this helped to decrease allergic cosmetic dermatitis. Towards the end of the 20th century, the rate of positives among cosmetic sensitizers decreased to levels of 5% - 8% and have since maintained its rates into the 21th century. Currently, metal ions such as the likes of nickel have been identified as being the most common allergens found in cosmetics and cosmetic instruments. They often produce rosacea-like facial dermatitis and therefore allergen controlled soaps and cosmetics have been proved to be useful in recovering normal skin conditions.


1999 ◽  
Vol 26 (2) ◽  
pp. 133-162 ◽  
Author(s):  
Leslie S. Oakes ◽  
Mark A. Covaleski ◽  
Mark W. Dirsmith

This study compares organized labor's reactions to changing management rhetorics as these rhetorics surrounded accounting- based incentive plans, including profit sharing. Results suggest that labor's perceptions of profit sharing changed dramatically from the 1900–1930 period to post-World War II. The shift, in turn, prompts an exploration of two research questions: (1) how and why did the national labor discourse around the management rhetoric and its emphasis on accounting information change, and (2) how did this change render unions more governable in their support for accounting-based incentive plans?


2015 ◽  
Vol 46 (3) ◽  
pp. 449-456 ◽  
Author(s):  
R. Cooper ◽  
R. K. Blashfield

The DSM-I is currently viewed as a psychoanalytic classification, and therefore unimportant. There are four reasons to challenge the belief that DSM-I was a psychoanalytic system. First, psychoanalysts were a minority on the committee that created DSM-I. Second, psychoanalysts of the time did not use DSM-I. Third, DSM-I was as infused with Kraepelinian concepts as it was with psychoanalytic concepts. Fourth, contemporary writers who commented on DSM-I did not perceive it as psychoanalytic. The first edition of the DSM arose from a blending of concepts from the Statistical Manual for the Use of Hospitals of Mental Diseases, the military psychiatric classifications developed during World War II, and the International Classification of Diseases (6th edition). As a consensual, clinically oriented classification, DSM-I was popular, leading to 20 printings and international recognition. From the perspective inherent in this paper, the continuities between classifications from the first half of the 20th century and the systems developed in the second half (e.g. DSM-III to DSM-5) become more visible.


Gesnerus ◽  
2010 ◽  
Vol 67 (2) ◽  
pp. 217-540
Author(s):  
Catherine Fussinger

Based on a critique of the traditional ruling of mental hospital, therapeutic community is an innovative model elaborated in Great Britain during World War II. According to this approach, all the relationships at work inside the institution have a big impact on the patients’ state. One of the favoured tools of the therapeutic community lies in regular meetings common to patients and staff, but also reserved to professionals. During these sessions small and big problems are intended to be discussed and resolved collectively. The constitution of this approach as a model and its diffusion in continental European psychiatry during the second half of the 20th century is described in this paper. Four stages are distinguished: the genesis, the constitution of a distinct approach and diffusion in Continental Europe, the radicalisation and criticism by the antipsychiatric movement, the institutionalisation and decline.


World Science ◽  
2019 ◽  
Vol 4 (11(51)) ◽  
pp. 37-40
Author(s):  
Tsitsino Bukia ◽  
Nana Parinos

A war correspondent has no border, no gender, no religion or race. The only thing a war reporter has - the skills of delivering truth, reflection of the reality in the way it is.The soviet space was absolutely closed to journalism and combat women journalists’ involvement in wars. The field almost consisted of males. Consequently, it seems impossible to analyze and compare the technique of writing of American and SovietWomen. If America freely accepts women for being actively involved in covering war activities, the Soviets obviously refused to do so.The role of a war correspondent is much bigger than one can suppose. Being a war reporter is more than implementing their responsibilities. It goes deeper into the history. A professional combat reporter is a historian facing the history and keeping it for the next generation.The paper considers advantages and disadvantages of being a female combat correspondent in the Soviet space and the United States of America.The role of American and Soviet women reporters in covering WWII.


2020 ◽  
Vol 9 (1) ◽  
pp. 21-48
Author(s):  
Elżbieta Dynia

The article concerns international recognition of the Polish state established after World War I in the year 1918, the Polish state and the status of Poland in terms of international law during World War II and after its conclusion until the birth of the Third Polish Republic in the year 1989. A study of related issues confirmed the thesis of the identity and continuity of the Polish state by international law since the year 1918, as solidified in Polish international law teachings, and showed that the Third Polish Republic is, under international law, not a new state, but a continuation of both the Second Polish Republic as well as the People’s Republic of Poland.


2018 ◽  
Vol 3 ◽  
pp. 1-34
Author(s):  
Lorne D. Bruce

This article undertakes a historical survey of university and college library developments in Canada between 1945 and 1960. It examines contemporary accounts in relation to library architecture, the acquisition and organization of collections, administrative library structures and staffing, services for faculty and students, and efforts by librarians to realize professional standing. A national review of academic libraries and librarianship expands our knowledge beyond the typical themes applied to this era: "growth" and "progress." The architectural redefinition of libraries, the impetus to establish research collections, the maturation of academic librarianship, and the increasing complexity of library operations were prominent features in the postwar period. The gradual evolution of academic libraries towards more-uniform organizational purposes and structures on a national basis following World War II can be considered a period of “midcentury modernization” that preceded the more memorable and better documented decades of the 1960s and later.


2013 ◽  
Vol 38 (1) ◽  
pp. 37-52
Author(s):  
Balázs Fekete

This article discusses the revival of comparative law in Hungarian Socialist jurisprudence. Prior to World War II, the development of comparative law generally had followed international trends; however, it was disrupted at both a personal and an institutional level at the end of the 1940s due to the Marxist-Leninist turn of legal thinking that accompanied the introduction of a Communist regime in the country. Nonetheless, this rejection of comparative law was gradually replaced by a more open attitude that strongly supported participation in the international comparative-law movement from the 1960s. Imre Szabó and Gyula Eörsi played a prominent role in this transformation. They legitimized the use of comparative methods in Socialist jurisprudence and, also, created a plausible conceptual framework for Socialist comparative law.


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