scholarly journals Resting-State Blood Oxygen Level-Dependent Functional MRI: A Paradigm Shift in Preoperative Brain Mapping

2015 ◽  
Vol 93 (6) ◽  
pp. 427-439 ◽  
Author(s):  
Eric C. Leuthardt ◽  
Monica Allen ◽  
Mudassar Kamran ◽  
Ammar H. Hawasli ◽  
Abraham Z. Snyder ◽  
...  
Keyword(s):  
Functional Mri ◽  
Brain Mapping ◽  
Resting State ◽  
Paradigm Shift ◽  
Blood Oxygen Level Dependent ◽  
Blood Oxygen ◽  
Oxygen Level ◽  
Blood Oxygen Level

Effects of Methylphenidate on Functional MRI Blood-Oxygen-Level-Dependent Contrast

2000 ◽  
Vol 157 (10) ◽  
pp. 1697-1699 ◽  
Author(s):  
Stephen M. Rao ◽  
Betty Jo Salmeron ◽  
Sally Durgerian ◽  
Judi A. Janowiak ◽  
Mariellen Fischer ◽  
...  
Keyword(s):  
Functional Mri ◽  
Blood Oxygen Level Dependent ◽  
Blood Oxygen ◽  
Oxygen Level ◽  
Blood Oxygen Level

Effects of methylphenidate on functional MRI blood oxygen level dependent (BOLD) contrast

NeuroImage ◽  
2000 ◽  
Vol 11 (5) ◽  
pp. S769
Author(s):  
Judi A. Janowiak ◽  
Betty Jo Salmeron ◽  
Sally Durgerian ◽  
Mariellen Fischer ◽  
Robert C. Risinger ◽  
...  
Keyword(s):  
Functional Mri ◽  
Blood Oxygen Level Dependent ◽  
Blood Oxygen ◽  
Oxygen Level ◽  
Blood Oxygen Level

Implementation of spin-echo blood oxygen level-dependent (BOLD) functional MRI in birds

2010 ◽  
Vol 23 (9) ◽  
pp. 1027-1032 ◽  
Author(s):  
Colline Poirier ◽  
Marleen Verhoye ◽  
Tiny Boumans ◽  
Annemie Van der Linden
Keyword(s):  
Functional Mri ◽  
Spin Echo ◽  
Blood Oxygen Level Dependent ◽  
Blood Oxygen ◽  
Oxygen Level ◽  
Blood Oxygen Level

scholarly journals Differential Modulating Effect of Acupuncture in Patients With Migraine Without Aura: A Resting Functional Magnetic Resonance Study

2021 ◽  
Vol 12 ◽  
Author(s):  
Shanshan Liu ◽  
Shilei Luo ◽  
Tianwei Yan ◽  
Wen Ma ◽  
Xiangyu Wei ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Therapeutic Effect ◽  
Resting State ◽  
Migraine Without Aura ◽  
Blood Oxygen Level Dependent ◽  
Blood Oxygen ◽  
Oxygen Level ◽  
Functional Magnetic Resonance ◽  
Blood Oxygen Level ◽  
Migraine Group

Introduction: Migraine is a recurrent neurological disorder, the symptoms of which can be significantly relieved by acupuncture. However, the central mechanism via which acupuncture exerts its therapeutic effect in migraine is unclear. The aim of this study was to compare the differences in regional homogeneity (ReHo) between patients with migraine without aura (MwoA) and healthy controls (HCs) and to explore the immediate and cumulative therapeutic effect of acupuncture in patients with MwoA using resting-state functional magnetic resonance imaging (fMRI).Methods: The study subjects were 40 patients with MwoA and 16 matched HCs. The patients with MwoA received acupuncture on 2 days per week for 6 weeks for a total of 12 sessions followed by 24 weeks of follow-up. The primary clinical efficacy outcomes were the number of days with migraine and the average severity of headache. Secondary outcomes were the Migraine-Specific Quality of Life Questionnaire, Self-Rating Anxiety Scale, and Self-Rating Depression Scale scores. In the migraine group, resting-state blood-oxygen-level-dependent fMRI scans were obtained at baseline and after the first and 12th acupuncture sessions to measure the ReHo value. In the HCs, only a baseline resting-state blood-oxygen-level-dependent fMRI scan was obtained.Results: Compared with the control group, the migraine group had a significantly lower ReHo value in the cerebellum, which increased after the first acupuncture session. Long-term acupuncture significantly improved migraine symptoms and mood with a therapeutic effect that lasted for at least 6 months. After 12 acupuncture sessions, there were significant increase of cerebellum and angular gyrus in the migraine group.Conclusion: These findings suggest that migraine is related to cerebellar dysfunction. Acupuncture can relieve the symptoms of migraine, improve dysfunction of cerebellum, and activate brain regions involved in modulation of pain and emotion The cumulative therapeutic effect of acupuncture is more extensive and significant than its immediate effect.

scholarly journals Evaluating Cognitive Relationships with Resting-State and Task-driven Blood Oxygen Level-Dependent Variability

2021 ◽  
Vol 33 (2) ◽  
pp. 279-302
Author(s):  
Peter R. Millar ◽  
Beau M. Ances ◽  
Brian A. Gordon ◽  
Tammie L. S. Benzinger ◽  
John C. Morris ◽  
...  
Keyword(s):  
Task Performance ◽  
Resting State ◽  
Attentional Control ◽  
Blood Oxygen Level Dependent ◽  
Blood Oxygen ◽  
Bold Signal ◽  
Oxygen Level ◽  
Blood Oxygen Level ◽  
Age Related ◽  
And Task

Recent functional magnetic resonance imaging studies have reported that moment-to-moment variability in the blood oxygen level-dependent (BOLD) signal is positively associated with task performance and, thus, may reflect a behaviorally sensitive signal. However, it is not clear whether estimates of resting-state and task-driven BOLD variability are differentially related to cognition, as they may be driven by distinct sources of variance in the BOLD signal. Moreover, other studies have suggested that age differences in resting-state BOLD variability may be particularly sensitive to individual differences in cardiovascular, rather than neural, factors. In this study, we tested relationships between measures of behavioral task performance and BOLD variability during both resting-state and task-driven runs of a Stroop and an animacy judgment task in a large, well-characterized sample of cognitively normal middle-aged to older adults. Resting-state BOLD variability was related to composite measures of global cognition and attentional control, but these relationships were eliminated after correction for age or cardiovascular estimates. In contrast, task-driven BOLD variability was related to attentional control measured both inside and outside the scanner, and importantly, these relationships persisted after correction for age and cardiovascular measures. Overall, these results suggest that BOLD variability is a behaviorally sensitive signal. However, resting-state and task-driven estimates of BOLD variability may differ in the degree to which they are sensitive to age-related, cardiovascular, and neural mechanisms.

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