The Effectiveness of Lactobacillus Beverages in Controlling Infections among the Residents of an Aged Care Facility: A Randomized Placebo-Controlled Double-Blind Trial

2015 ◽  
Vol 68 (1) ◽  
pp. 51-59 ◽  
Author(s):  
Satoru Nagata ◽  
Takashi Asahara ◽  
Chongxin Wang ◽  
Yumi Suyama ◽  
Osamu Chonan ◽  
...  
Keyword(s):  
Acetic Acid ◽  
Care Facility ◽  
The Elderly ◽  
Fermented Milk ◽  
Aged Care ◽  
Double Blind ◽  
Blind Test ◽  
Staff Members ◽  
Significant Difference ◽  
Bowel Movements

Backgrounds/Aims: To clarify the usefulness of Lactobacillus casei strain Shirota (LcS)-fermented milk in the normalization of bowel movements and improvement of infection control for the elderly residents and staff of facilities for the elderly. Methods: A randomized placebo-controlled double-blind test was performed among the elderly residents (average age, 85) and staff members (average age, 37) of facilities for the elderly. The participants randomly received either LcS-fermented milk or a placebo beverage once daily for 6 months. Clinical data and enteric conditions were compared between the 2 groups. Results: A significantly lower incidence of fever and improved bowel movements were seen in the LcS-fermented milk group (n = 36) in comparison to the placebo group (n = 36). The numbers of Bifidobacterium and Lactobacillus were significantly higher (p < 0.01), the numbers of destructive bacteria such as Clostridium difficile were significantly lower (p < 0.05), and the fecal acetic acid concentration and total acidity were significantly higher in the LcS group. A significant difference in the intestinal microbiota, fecal acetic acid, and pH was also observed between the LcS and placebo groups among the facility's staff members. Conclusions: The long-term consumption of LcS-fermented milk may be useful for decreasing the daily risk of infection and improving the quality of life among the residents and staff of facilities for the elderly.

scholarly journals Effects of Fermented Milk Containing Lacticaseibacillus paracasei Strain Shirota on Constipation in Patients with Depression: A Randomized, Double-Blind, Placebo-Controlled Trial

Nutrients ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 2238
Author(s):  
Xiaomei Zhang ◽  
Shanbin Chen ◽  
Ming Zhang ◽  
Fazheng Ren ◽  
Yimei Ren ◽  
...  
Keyword(s):  
Mental Illness ◽  
Placebo Group ◽  
Rating Scale ◽  
Controlled Trial ◽  
Fermented Milk ◽  
Daily Consumption ◽  
Double Blind ◽  
Tnf Α ◽  
Significant Difference ◽  
Factor Α

Probiotics have been shown to benefit patients with constipation and depression, but whether they specifically alleviate constipation in patients with depression remains unclear. The aim of this study was to investigate the effect of Lacticaseibacillus paracasei strain Shirota (LcS), formerly Lactobacillus casei strain Shirota, on constipation in patients with depression with specific etiology and gut microbiota and on depressive regimens. Eighty-two patients with constipation were recruited. The subjects consumed 100 mL of a LcS beverage (108 CFU/mL) or placebo every day for 9 weeks. After ingesting beverages for this period, we observed no significant differences in the total patient constipation-symptom (PAC-SYM) scores in the LcS group when compared with the placebo group. However, symptoms/scores in item 7 (rectal tearing or bleeding after a bowel movement) and items 8–12 (stool symptom subscale) were more alleviated in the LcS group than in the placebo group. The Beck Depression Index (BDI) and Hamilton Depression Rating Scale (HAMD) scores were all significantly decreased, and the degree of depression was significantly improved in both the placebo and LcS groups (p < 0.05), but there was no significant difference between the groups. The LcS intervention increased the beneficial Adlercreutzia, Megasphaera and Veillonella levels and decreased the bacterial levels related to mental illness, such as Rikenellaceae_RC9_gut_group, Sutterella and Oscillibacter. Additionally, the interleukin (IL)-1β, IL-6, and tumor necrosis factor-α (TNF-α) levels were significantly decreased in both the placebo and LcS groups (p < 0.05). In particular, the IL-6 levels were significantly lower in the LcS group than the placebo group after the ingestion period (p < 0.05). In conclusion, the daily consumption of LcS for 9 weeks appeared to relieve constipation and improve the potentially depressive symptoms in patients with depression and significantly decrease the IL-6 levels. In addition, the LcS supplementation also appeared to regulate the intestinal microbiota related to mental illness.

scholarly journals Remodelling Aged Living to Reduce Stigma

2021 ◽  
Author(s):  
Georgia Reece
Keyword(s):  
Social Isolation ◽  
Care Facility ◽  
The Elderly ◽  
Aged Care ◽  
Facility Design ◽  
Community Based ◽  
Aged Care Facility ◽  
Iterative Design ◽  
Care Facilities ◽  
Aged Care Facilities

<p><b>This thesis investigates whether community-based architectural strategies can be used in aged care facility design to reduce the stigma of social isolation. New Zealand has a growing population, with an increasing number of people needing assistance from aged care facilities. However, the elderly resist moving into aged care facilities because of fears of marginalisation, social isolation and associated stigma. Stigma creates outcomes of discrimination towards marginalised individuals, resulting in negative projections on these people and consequent social exclusion. </b></p> <p>There are two main aims of this research. The first aim was to understand the relationship between stigma and architecture and stigma and aged care facilities. To achieve this aim, stigma and various strategies for addressing that stigma in aged care facilities were defined based on contemporary literature on this subject and analyses of relevant built precedents. </p> <p>The second aim was to develop, a contemporary aged care facility that demonstrates potential strategies for reducing stigma. This aim was achieved by developing criteria that respond to iterative design exercises and contemporary research in the fields of aged care facilities, architecture and stigma. An iterative design process, continually tested these criteria against literature and precedent reviews, was carried out to arrive at a coherent design and more refined set of criteria. </p> <p>Research conclusions showed that community-based architectural strategies can be used to reduce the stigma of social isolation in aged care facility design. This resulted in the outcome of a community-based model and criteria that can be applied to the design of aged care facilities and will resultantly provide residents with a purposive role and inclusion within society.</p>

scholarly journals Uncharted Waters: Influencing Practice Through a Life Course Approach: How Caregivers' Life Experience Can Influence the Care They Give to the Elderly at the End of Life

2021 ◽  
Author(s):  
◽  
Katherine Anne Gellatly
Keyword(s):  
Palliative Care ◽  
End Of Life ◽  
Life Experience ◽  
Life Story ◽  
Care Pathway ◽  
Care Facility ◽  
The Elderly ◽  
Aged Care ◽  
Nurse Specialist ◽  
Insight Into

<p>This project originates from my experience as a Palliative Care Nurse Specialist Educator working from a hospice environment. Observations and collaborative partnerships with staff in Aged Care Facilities provided insight into the palliative care needs of the residents at the end-of-life. Care Assistants (caregivers) provide the majority of direct care and spend most time with residents, with little training for providing that care, to residents with increasingly complex needs. A two phase exploratory descriptive project was designed using the life course research paradigm and life story narrative research to consider what life experience caregivers brought to their caregiving role in an Aged Care Facility in New Zealand and what influence education had on their work life. In the first phase a focus group, following education and the implementation of the Liverpool Care Pathway, was conducted and themes identified from an interdisciplinary staff team discussion. In phase two of the project four of the caregivers participated in a life story interview. The thematic analysis of these transcripts provided insight into the four caregivers' life experience. A novel method termed poetic condensation was used in the study to identify the essence of each person's life story. The researcher then reflected on each of the four life stories and identified the turning point in the person's life and a caring moment from the transcript. The discussion in the thesis reveals the impact of the education sessions and implementation of the Liverpool Care Pathway on the caregivers' practice and how this became a turning point in the delivery of care for the elderly residents particularly those who were dying in the Aged Care Facility. The researcher concludes the thesis by recognizing that her role as a palliative care clinical nurse specialist and educator is necessary to transfer specialist end-of-life knowledge and mentor staff as they shape best end-of-life practice.</p>

scholarly journals Uncharted Waters: Influencing Practice Through a Life Course Approach: How Caregivers' Life Experience Can Influence the Care They Give to the Elderly at the End of Life

2021 ◽  
Author(s):  
◽  
Katherine Anne Gellatly
Keyword(s):  
Palliative Care ◽  
End Of Life ◽  
Life Experience ◽  
Life Story ◽  
Care Pathway ◽  
Care Facility ◽  
The Elderly ◽  
Aged Care ◽  
Nurse Specialist ◽  
Insight Into

<p>This project originates from my experience as a Palliative Care Nurse Specialist Educator working from a hospice environment. Observations and collaborative partnerships with staff in Aged Care Facilities provided insight into the palliative care needs of the residents at the end-of-life. Care Assistants (caregivers) provide the majority of direct care and spend most time with residents, with little training for providing that care, to residents with increasingly complex needs. A two phase exploratory descriptive project was designed using the life course research paradigm and life story narrative research to consider what life experience caregivers brought to their caregiving role in an Aged Care Facility in New Zealand and what influence education had on their work life. In the first phase a focus group, following education and the implementation of the Liverpool Care Pathway, was conducted and themes identified from an interdisciplinary staff team discussion. In phase two of the project four of the caregivers participated in a life story interview. The thematic analysis of these transcripts provided insight into the four caregivers' life experience. A novel method termed poetic condensation was used in the study to identify the essence of each person's life story. The researcher then reflected on each of the four life stories and identified the turning point in the person's life and a caring moment from the transcript. The discussion in the thesis reveals the impact of the education sessions and implementation of the Liverpool Care Pathway on the caregivers' practice and how this became a turning point in the delivery of care for the elderly residents particularly those who were dying in the Aged Care Facility. The researcher concludes the thesis by recognizing that her role as a palliative care clinical nurse specialist and educator is necessary to transfer specialist end-of-life knowledge and mentor staff as they shape best end-of-life practice.</p>

scholarly journals Subjective memory complaints in the elderly may be related to factors other than cognitive deficit

2010 ◽  
Vol 4 (1) ◽  
pp. 54-57 ◽  
Author(s):  
Ana Cristina Procópio de Oliveira Aguiar ◽  
Miriam Ikeda Ribeiro ◽  
Alessandro Ferrari Jacinto
Keyword(s):  
Rating Scale ◽  
Care Facility ◽  
The Elderly ◽  
Cognitive Status ◽  
Subjective Memory Complaints ◽  
Subjective Memory ◽  
Extrinsic Factors ◽  
Term Care ◽  
Memory Complaints ◽  
Significant Difference

Abstract Prevalence of subjective memory complaints (SMC) in elderly community dwellers (ECD) ranges from 25 to 50%. Some controversy exists over the association between SMC and cognitive status. Objective: We investigated whether a correlation in cognitive performance existed between two different groups according to SMC. Methods: The Mini Mental State Examination (MMSE) and Dementia Rating Scale-Mattis (DRS-Mattis) were applied to two groups: ECD (n=14) with SMC and residents (n=14) of a long-term care facility (LTCF) without SMC. Results: The median age in the ECD group was 81.0 years, and in the LTCF group was 75.0 years. There was a statistically significant difference (p=0.048) between these groups regarding age. Concerning schooling (1-8 or ³9 years), there was no statistically significant difference between the groups (p=0.638). No statistically significant difference between the two groups was found for scores on the cognitive tests. Conclusion: SMC might be related to extrinsic factors other than insipient cognitive decline.

Temporal Characteristics of Habitual Physical Activity Periods Among Older Adults

2009 ◽  
Vol 6 (5) ◽  
pp. 644-650 ◽  
Author(s):  
Thorlene Egerton ◽  
Sandra G. Brauer
Keyword(s):  
Physical Activity ◽  
Older People ◽  
Care Facility ◽  
The Elderly ◽  
Aged Care ◽  
Activity Period ◽  
Activity Levels ◽  
Activity Data ◽  
Temporal Characteristics ◽  
At Home

Background:While physical activity is advocated for the elderly, little is known about the patterns of habitual activity of older people, particularly those in aged care. This study employed a novel approach to analyzing activity data to compare the temporal characteristics of daily activity between 15 older people living at home with 16 living in an aged care facility.Methods:The time spent standing and walking, and the number and duration of upright activity periods (greater than 1 minute) were monitored for 72 hr continuously.Results:Despite variation in all measures across the participants, those living in aged care spent significantly less time upright per day (2.3 hr vs. 7.2 hr), standing (1.6 hr vs. 5 hr), and walking (0.7 hr vs. 2.2 hr) than those living at home. Participants in both groups had a similar number of activity periods; however, the median activity period duration was less for those living in aged care (4 min vs. 8 min).Conclusions:Activity levels of both groups were low compared with recommendations. In particular, aged care residents were rarely upright for 30 min continuously, supporting the need for services to promote physical activity of older people particularly those living in aged care facilities.

Rivastigmine in the treatment of delirium in older people: a pilot study

2010 ◽  
Vol 22 (5) ◽  
pp. 812-818 ◽  
Author(s):  
Ross Overshott ◽  
Martin Vernon ◽  
Julie Morris ◽  
Alistair Burns
Keyword(s):  
Placebo Group ◽  
Pilot Study ◽  
The Elderly ◽  
Confusion Assessment Method ◽  
Assessment Method ◽  
Double Blind ◽  
Significant Difference ◽  
Medical Wards ◽  
To Receive ◽  
Negative Health Outcomes

ABSTRACTBackground: Delirium is common in the elderly and is associated with high mortality and negative health outcomes. Reduced activity in the cholinergic system has been implicated in the pathogenesis of delirium. Cholinesterase inhibitors, which increase cholinergic activity, may therefore be beneficial in the treatment of delirium.Methods: This is a double-blind, placebo-controlled randomized pilot study of the treatment of delirium with a cholinesterase inhibitor of patients admitted to hospital medical wards. Patients over the age of 65 years were identified as having delirium by the Confusion Assessment Method (CAM). Patients with delirium were randomized to receive rivastigmine 1.5 mg once a day increasing to 1.5 mg twice a day after seven days or an identical placebo (two tablets after seven days).Results: Fifteen patients entered the trial; eight received rivastigmine and seven received placebo. All of the rivastigmine group, but only three of the placebo group, were negative for delirium on the CAM when they left the study and eventually discharged home. There was no significant difference in the duration of delirium between the two groups (rivastigmine group 6.3 days versus placebo group 9.9 days, p = 0.5, 95% confidence interval −15.6–8.4).Conclusions: The numbers of patients who screened positive for delirium was very small and as a result the sample size was too small to make any meaningful inferences about treatment of delirium. Despite the small numbers included in the study, there are some indicators that rivastigmine may be safe and effective in treating delirium.

scholarly journals Remodelling Aged Living to Reduce Stigma

2021 ◽  
Author(s):  
Georgia Reece
Keyword(s):  
Social Isolation ◽  
Care Facility ◽  
The Elderly ◽  
Aged Care ◽  
Facility Design ◽  
Community Based ◽  
Aged Care Facility ◽  
Iterative Design ◽  
Care Facilities ◽  
Aged Care Facilities

<p><b>This thesis investigates whether community-based architectural strategies can be used in aged care facility design to reduce the stigma of social isolation. New Zealand has a growing population, with an increasing number of people needing assistance from aged care facilities. However, the elderly resist moving into aged care facilities because of fears of marginalisation, social isolation and associated stigma. Stigma creates outcomes of discrimination towards marginalised individuals, resulting in negative projections on these people and consequent social exclusion. </b></p> <p>There are two main aims of this research. The first aim was to understand the relationship between stigma and architecture and stigma and aged care facilities. To achieve this aim, stigma and various strategies for addressing that stigma in aged care facilities were defined based on contemporary literature on this subject and analyses of relevant built precedents. </p> <p>The second aim was to develop, a contemporary aged care facility that demonstrates potential strategies for reducing stigma. This aim was achieved by developing criteria that respond to iterative design exercises and contemporary research in the fields of aged care facilities, architecture and stigma. An iterative design process, continually tested these criteria against literature and precedent reviews, was carried out to arrive at a coherent design and more refined set of criteria. </p> <p>Research conclusions showed that community-based architectural strategies can be used to reduce the stigma of social isolation in aged care facility design. This resulted in the outcome of a community-based model and criteria that can be applied to the design of aged care facilities and will resultantly provide residents with a purposive role and inclusion within society.</p>

scholarly journals Neurocognitive Effects of Cocoa and Red-Berries Consumption in Healthy Adults

Nutrients ◽  
2021 ◽  
Vol 14 (1) ◽  
pp. 1
Author(s):  
Joaquín García-Cordero ◽  
Alicia Pino ◽  
Constanza Cuevas ◽  
Verónica Puertas-Martín ◽  
Ricardo San Román ◽  
...  
Keyword(s):  
Verbal Learning ◽  
Growth Factor Receptor ◽  
Population Group ◽  
The Elderly ◽  
Tower Of London ◽  
Double Blind ◽  
Adult Intelligence Scale ◽  
Wechsler Adult Intelligence Scale ◽  
Age Related ◽  
Significant Difference

In recent decades, the elderly population has increased at higher rates than any other population group, resulting in an increase in age-related diseases such as neurodegenerative and cognitive impairment. To address this global health problem, it is necessary to search for new dietary strategies that can prevent the main neurocognitive problems associated with the ageing process. Therefore, the aim of the present study was to analyze the effect of cocoa flavanols and red berry anthocyanins on brain-derived neurotrophic factor (BDNF) and nerve growth factor receptor (NGF-R) and to stablish the possible improvement in cognitive performance by using a battery of neurocognitive tests that included the Verbal Learning Test Spain-Complutense, the Spatial Recall Test 10/36 BRB-N, the Wechsler Adult Intelligence Scale III and IV, the STROOP Task and the Tower of London Test. A randomized, double-blind, parallel-group study was performed in 60 healthy volunteers between 50 and 75 years old who consumed a cocoa powder, a red berries mixture or a combination of both for 12 weeks. After the intervention, we observed a reduction in the time needed to start (p = 0.031) and finish (p = 0.018) the neurocognitive test known as the Tower of London in all groups, but the decrease in time to finish the task was more pronounced in the intervention with the combination of cocoa-red berries group. We failed to show any significant difference in BDNF and NGF-R sera levels. However we found a negative correlation between BDNF and the number of movements required to finish the TOL in women (p = 0.044). In conclusion, our study showed an improvement in executive function, without any change in neurotrofin levels, for all intervention arms.

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