scholarly journals Five Simultaneous Primary Tumors in a Single Patient: A Case Report and Review of the Literature

2015 ◽  
Vol 8 (3) ◽  
pp. 432-438 ◽  
Author(s):  
Casey W. Williamson ◽  
Anthony Paravati ◽  
Majid Ghassemi ◽  
Kristine Lethert ◽  
Patricia Hua ◽  
...  
Keyword(s):  
B Cell Lymphoma ◽  
Tendon Sheath ◽  
Pigmented Villonodular Synovitis ◽  
Review Of The Literature ◽  
Primary Malignancy ◽  
Primary Tumors ◽  
Multiple Primary Malignancies ◽  
Lobular Breast Carcinoma ◽  
Personalized Approach ◽  
The Right

Multiple primary malignancies (MPMs) are present when a patient is diagnosed with more than one primary malignancy and when each tumor is histologically unrelated to the others. MPMs are considered synchronous when they present within 6 months of one another. Here, we report the case of a 57-year-old woman with a past medical history significant for melanoma in 1988, who presented in 2014 with 5 distinct tumors within 4 months: malignant melanoma of the right popliteal fossa, invasive lobular breast carcinoma, diffuse large B cell lymphoma, nodular lymphocyte predominant Hodgkin lymphoma, and a giant cell tumor of tendon sheath/pigmented villonodular synovitis. We discuss her treatment and also present a brief review of the literature. The incidence of MPMs appears to be on the rise, which demands an interdisciplinary, multimodal, and personalized approach to care.

Glomus Jugulare Tumor Presenting as Deep Vein Thrombosis

2018 ◽  
Vol 1 ◽  
pp. 11
Author(s):  
Maria Zambrano ◽  
Yoon Ko ◽  
Vikram S Dogra
Keyword(s):  
Deep Vein Thrombosis ◽  
Jugular Vein ◽  
Filling Defect ◽  
Review Of The Literature ◽  
Primary Tumors ◽  
Glomus Jugulare Tumor ◽  
Vein Thrombosis ◽  
Glomus Jugulare ◽  
The Right ◽  
Deep Vein

Intraluminal filling defect and non-compressibility of the vein are diagnostic of a deep vein thrombosis (DVT). However, other etiologies can present with features similar to DVTs; these include tumors extending into the vein and primary tumors arising from the vein such as leiomyosarcoma and hemangioendothelioma. Here, we present a case of an 80-year-old female with a right glomus jugulare tumor (GJT) with extension into the right internal jugular vein mimicking a DVT. This case report presents the sonographic features of GJT presenting as DVT and review of the literature of other tumors that can present in a similar fashion.

scholarly journals P650 A rare form of cardiac mass: primary cardiac lymphoma

2020 ◽  
Vol 21 (Supplement_1) ◽  
Author(s):  
B Yagmur ◽  
E Simsek ◽  
B Ozbay ◽  
T Calkavur ◽  
M Kayikcioglu ◽  
...  
Keyword(s):  
B Cell Lymphoma ◽  
Cardiac Mass ◽  
Mass Lesion ◽  
Cardiac Tumors ◽  
Rare Form ◽  
Primary Tumors ◽  
Cardiac Lymphoma ◽  
Primary Cardiac Lymphoma ◽  
Vena Cava Superior ◽  
The Right

Abstract Funding Acknowledgements We declare no conflict of interest and no financial support A rare form of cardiac mass primary cardiac lymphoma Introduction Primary tumors of the heart are rare and constitute 5% of all cardiac masses. Primary cardiac lymphoma is a curable form of cancer that responds well to early diagnosis and chemotherapy. Case report 56 year old male patient presented to our outpatient clinic with abdominal swelling. Echocardiography revealed a mass lesion that surrounded the right ventricle and restricted ventricular diastolic function. The mass lesion was poorly discernable from normal myocardial tissue. Magnetic resonance imaging (MRI) showed an infiltrative mass lesion that filled the right pericardial space, and that surrounded the junction between vena cava superior and the right atrium, as well as the root of the aorta. Subxyphoidal biopsy revealed diffuse large B cell lymphoma. Patient died on the 10th day of chemotherapy. Discussion Primary cardiac lymphoma constitutes only 2% of all primary cardiac tumors. Cardiac lymphomas are curable in early stages with chemotherapy without the need for surgical excision. Cardiac lymphoma should be kept in mind when faced with a cardiac mass lesion and imaging modalities such as MRI and PET scanning and tissue biopsy should be utilized before planning surgical interventions since these lesions respond well to chemotherapy Abstract P650 Figure.

scholarly journals Primary Appendix Lymphoma: Case Report and Review of the Literature

Acta Medica ◽  
2018 ◽  
Vol 49 (3) ◽  
pp. 41 ◽  
Author(s):  
Burak Ardicli ◽  
Ayse Karaman ◽  
Sule Yesil ◽  
Nilufer Arda ◽  
Gurses Sahin ◽  
...  
Keyword(s):  
Case Report ◽  
Acute Appendicitis ◽  
B Cell ◽  
Surgical Procedure ◽  
Cell Lymphoma ◽  
B Cell Lymphoma ◽  
Pathological Examination ◽  
Review Of The Literature ◽  
Primary Tumors ◽  
Other Neoplasms

Appendectomy is the most frequent emergent surgical procedure in childhood. Carcinomas are the most frequent neoplasms in the appendix, other neoplasms such as carcinoid tumors and lymphomas may seen less frequently. Primary tumors of the appendix are very rare. We report a patient presented with acute appendicitis diagnosed with B-cell lymphoma after pathological examination.

scholarly journals Cardiac Angiosarcoma:A case report and review of the literature

2021 ◽  
Author(s):  
Limin Luo ◽  
Weipeng Zhao ◽  
Kun Liu
Keyword(s):  
Case Report ◽  
Malignant Tumors ◽  
Right Atrial ◽  
Cardiac Tumors ◽  
Review Of The Literature ◽  
Primary Tumors ◽  
Cardiac Angiosarcoma ◽  
Right Atrial Appendage ◽  
The Right ◽  
Primary Cardiac Tumors

Primary cardiac tumors are extremely rare.Most primary tumors are benign,and malignant tumors comprise about 15%1.Angiosarcoma is the most common type of primary cardiac malignant tumors.Compared with the left atrium or ventricle,the tumor prefer to occur in the right atrium or ventricle,especially the right atrium.In this case report,we present the case of a 32-year-old female with cardiac angiosarcoma primary to the right atrial appendage(RAA).

scholarly journals Radiographic Thrombus within the External Jugular Vein: Report of a Rare Case and Review of the Literature

2015 ◽  
Vol 2015 ◽  
pp. 1-4 ◽  
Author(s):  
Sayyad Yaseen Zia ◽  
Richard L. Bakst ◽  
Qiusheng Si ◽  
Mike Yao ◽  
Peter M. Som
Keyword(s):  
Jugular Vein ◽  
Clinical Manifestations ◽  
External Jugular Vein ◽  
Review Of The Literature ◽  
Primary Malignancy ◽  
Target Delineation ◽  
Radiologic Findings ◽  
Palliative Radiation Therapy ◽  
The Right

We are reporting a case of a 91-year-old male with a primary malignancy of the right parotid gland with radiographic thrombus extension within the right external jugular vein. He was treated with palliative radiation therapy to the right parotid mass with a marked clinical response. The rarity of this occurrence as documented in the review of the literature provides for uncertainty with regard to proper management. Radiographic evidence of thrombus in the absence of clinical manifestations, the role of anticoagulation, and the proper radiation target delineation were all challenges encountered in the care of this patient. Our case represents a rare occurrence with unique radiologic findings that has implications for management.

scholarly journals Non-Hodgkin’s Lymphoma Presenting as Isolated Peritoneal Lymphomatosis: A Case Report and Literature Review

2021 ◽  
Vol 11 ◽  
Author(s):  
Min Zhu ◽  
Zhixuan Wu ◽  
Zhaoxia Yang ◽  
Bo Ning ◽  
Shengjie Yu ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Peritoneal Carcinomatosis ◽  
Poor Prognosis ◽  
Cell Lymphoma ◽  
B Cell Lymphoma ◽  
Abdominal Distension ◽  
Review Of The Literature ◽  
Computed Tomography Scan ◽  
The Right ◽  
Tomography Scan

Peritoneal lymphomatosis is extremely rare and associated with poor prognosis. Most practitioners only pay more attention to peritoneal carcinomatosis. However, peritoneal lymphomatosis can be neglected and misdiagnosed. We report a teenager with 10 days of abdominal distension and pain accompanied by computed tomography scan suggesting diffuse thickening of the peritoneum and omentum and abdominopelvic effusion. Tuberculous peritonitis and peritoneal carcinomatosis were initially suspected. However, it was finally confirmed as non-Hodgkin’s B-cell lymphoma by omentum biopsies. He achieved complete remission after chemotherapy and autologous stem cell transplantation. But unfortunately, he suffered a relapse and died 10 months after diagnosis. Following a review of the literature, it can be concluded that the discovery of lymphomatosis in peritoneum is a rare finding. Lymphoma should be considered in the differential diagnosis of unexplained peritoneal thickening on computed tomography, and this case emphasizes the importance of early pathological diagnosis to make sure that the right treatment can be started opportunely.

Primary cutaneous B-cell lymphoma: narrative review of the literature

2019 ◽  
Vol 154 (4) ◽  
Author(s):  
Vieri Grandi ◽  
Silvia Alberti Violetti ◽  
Roberta La Selva ◽  
Stefano Cicchelli ◽  
Chiara Delfino ◽  
...  
Keyword(s):  
B Cell ◽  
Cell Lymphoma ◽  
B Cell Lymphoma ◽  
Narrative Review ◽  
Review Of The Literature ◽  
Cutaneous B Cell Lymphoma

Jurisprudence Study of the Importance of the Role of a Woman’s Right to Have a Child: A Review

2020 ◽  
Vol 16 (3) ◽  
pp. 188-193
Author(s):  
Fatemeh Ghodrati
Keyword(s):  
Pregnant Women ◽  
Civil Law ◽  
Google Scholar ◽  
Review Of The Literature ◽  
Maternal Role ◽  
The Right ◽  
Time Limitations ◽  
Natural Barrier ◽  
Taking Care

Background: Every woman has the right to have children. Objective: This study aimed to investigate the Jurisprudence study of the importance of the role of a woman right to have a child. Methods: A review of the literature with keywords of motherhood. The viewpoints of the jurists, jurisprudent law, right contraception and breastfeeding, spiritual rewards, pregnant women, instinct of having a child and the Quran. The Information Centers such as Scopus and Iranmedex, Magi ran SID, Google Scholar, Science Direct, Pub med, and in the returns without any time limitations up to 2018. Therefore, Qur'anic verses based on the topic and authentic Hadith texts as well as authoritative, authentic scientific articles. Results: Narrations and Quran verses on greatness and respect of a mother show the importance of the maternal role. The maternal role is a fabulous facet of perfection of a woman and Islam has considered spiritual rewards for it. In the Quran, many biological changes such as pregnancy, childbirth, breastfeeding and taking care of a child and spiritual characteristics of mothers as the instinct seeking a child or generosity towards child have been mentioned. Islamic rules have a duty to extend this culture and aid mothers to achieve this right. Nobody can deprive a woman of it. Conclusion: In view of jurisprudent rules in Islam, if there is no limitation or natural barrier for a woman to have a child but her husband’s illogical unwillingness for having a child; this is, according to article 1130 of civil law, a kind of distress and embarrassment and the woman has the right to divorce.

A Challenging Case of A Myeloid Sarcoma Misdiagnosed as High Grade B-Cell Lymphoma

2020 ◽  
Vol 154 (Supplement_1) ◽  
pp. S97-S97
Author(s):  
A Herrmann ◽  
B Mai ◽  
S Elzamly ◽  
A Wahed ◽  
A Nguyen ◽  
...  
Keyword(s):  
Bone Marrow ◽  
B Cell ◽  
Cell Lymphoma ◽  
B Cell Lymphoma ◽  
Myeloid Sarcoma ◽  
Proliferation Index ◽  
High Grade ◽  
Cell Markers ◽  
Thoracolumbar Region ◽  
The Right

Abstract Introduction/Objective A 46-year-old female presented with severe back pain associated with progressive bilateral lower extremity weakness and paresthesia, urinary retention, and constipation. Computed tomography revealed a retroperitoneal mass encasing the right psoas muscle, obstructing the right kidney, and extending to the thoracolumbar region resulting in severe spinal compression. An epidural tumor resection was subsequently performed at an outside hospital. Methods Histological sections showed sheets of blastoid neoplastic cells with intermediate to large nuclei, irregular membranes, fine chromatin, and prominent nucleoli. Immunohistochemical stains showed that these cells were positive for CD43, CD79a (weak, focal), BCL2, C-MYC, and PAX5 (weak, focal) and negative for CD10, CD20, CD30, ALK1, BCL6, MUM1, and Tdt. The Ki-67 proliferation index was 75-80%. With this immunophenotype, this patient was diagnosed with a high grade B-cell lymphoma and transferred to our institution for further work-up. On review of the slides, further immunohistochemical testing was requested which revealed positivity for CD117 and myeloperoxidase (MPO). Results The overall morphological and immunophenotypical features are most compatible with myeloid sarcoma (MS) with aberrant expression of B-cell markers and this patient’s diagnosis was amended. Interestingly, the patient’s bone marrow examination only showed 2% myeloblasts with left shifted granulocytosis and concurrent fluorescence in situ hybridization (FISH) studies were negative. Conclusion A literature review showed that 40-50% of MS are misdiagnosed as lymphoma. MS can frequently stain with B-cell or T-cell markers, as seen in this case, which makes it challenging for an accurate diagnosis and sub- classification. In addition, our case is interesting in that there was only extramedullary presentation without bone marrow involvement. Typically, MS develops after the diagnosis of acute myeloid leukemia (AML) with an incidence of 3–5% after AML. It can also manifest de novo in healthy patients, who then go on to develop AML months to years later. Therefore, this patient will require close follow-up.

Recurrence of Primary Breast Lymphoma Presenting as Bilateral Vitreoretinal Lymphoma

2021 ◽  
pp. 1-5
Author(s):  
Karishma Habbu ◽  
Roshan George ◽  
Miguel Materin
Keyword(s):  
Brain Mri ◽  
B Cell Lymphoma ◽  
Intrathecal Chemotherapy ◽  
Primary Breast Lymphoma ◽  
Blurred Vision ◽  
Breast Lymphoma ◽  
Central Nervous System Penetration ◽  
Vitreoretinal Lymphoma ◽  
The Right ◽  
Vitreous Biopsy

<b><i>Purpose:</i></b> This report describes a case of relapsed primary breast lymphoma (PBL) presenting as vitreoretinal lymphoma (VRL). <b><i>Methods:</i></b> We describe the clinical and hematopathologic findings in a patient with relapsed PBL involving the vitreous of both eyes. <b><i>Results:</i></b> A 59-year-old woman was treated for PBL with systemic and intrathecal chemotherapy 5 years prior to presentation. Three years later, she presented to an outside clinic with blurred vision in both eyes and bilateral vitritis. She was referred to our clinic with concern for ocular lymphoma. On presentation, the patient’s best-corrected visual acuity was 20/40 in the right eye and 20/25 in the left eye with 3+ vitreous cells in the right eye and 2+ vitreous cells in the left eye. Vitreous biopsy of the right eye revealed CD5-negative/CD10-negative B-cell lymphoma cells on flow cytometry. She had no evidence of disease on brain MRI, lumbar puncture, bone marrow biopsy, or full-body CT scans. She was treated with a regimen of rituximab, methotrexate, procarbazine, and vincristine for central nervous system penetration as well as multiple intraocular injections of methotrexate and rituximab with improvement in vision and ocular inflammation bilaterally. <b><i>Conclusion:</i></b> Relapsed PBL can present as bilateral VRL.

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