Short Sitting Height and Low Relative Sitting Height Are Associated with Severe Cognitive Impairment among Older Women in an Urban Community in China

2015 ◽  
Vol 45 (4) ◽  
pp. 257-263 ◽  
Author(s):  
Xiaoniu Liang ◽  
Xiantao Li ◽  
Ding Ding ◽  
Qianhua Zhao ◽  
Jianfeng Luo ◽  
...  

Background: Anthropometric indexes are powerful indicators of the environment and the plasticity of the human body. This study aimed at exploring the anthropometric indexes that are associated with late-life cognition impairment among the elderly Chinese in the Shanghai Aging Study. Methods: The height, weight, and sitting height of 3,741 participants were measured. Participants were diagnosed with ‘dementia', ‘mild cognitive impairment', or ‘cognitive normal' by neurologists using DSM-IV and Petersen criteria. Logistic regression was used to evaluate the association between height, sitting height, leg length or relative sitting height and cognitive function. Results: Participants with dementia had the shortest body height (mean 157.2 cm, SD 9.1), the shortest sitting height (mean 81.8 cm, SD 5.6), and the lowest relative sitting height (mean 52.0 cm, SD 1.9). After adjustment for age, gender, education, lifestyles, medical history, apolipoprotein genotype and weight, shorter sitting height (OR 1.08, 95% CI 1.01-1.16 per cm), longer leg length (OR 0.93, 95% CI 0.88-0.99 per cm), and lower relative sitting height (OR 1.17, 95% CI 1.04-1.31 per 1%) were found to be significantly associated with dementia in older women. Conclusions: The potential risks for late-life severe cognitive impairment may be related to health problems in childhood and slow growth during puberty in women.

Author(s):  
Duncan Robertson ◽  
Kenneth Rockwood ◽  
Paul Stolee

ABSTRACTA mental status questionnaire (MSQ) developed tor use in surveys of the non-institutionalized elderly has been validated against clinical assessment. The MSQ identities moderate and severe cognitive impairment in the elderly. However, using the suggested scoring subjects with mild impairment cannot be separated from normals.The test is short, acceptable and reproducible and rate for false-positives and false-negatives fall well within acceptable limits for use in estimating the prevalence of dementia in the non-institutionalized elderly population.


2016 ◽  
Vol 33 (S1) ◽  
pp. S190-S191
Author(s):  
G. Sobreira ◽  
M.A. Aleixo ◽  
C. Moreia ◽  
J. Oliveira

IntroductionDepression and mild cognitive impairment are common among the elderly. Half the patients with late-life depression also present some degree of cognitive decline, making the distinction between these conditions difficult.ObjectivesTo conduct a database review in order to understand the relationship between these entities, and treatment approaches.AimsTo create and implement clinical guidelines at our institution, to evaluate and treat elderly patients presenting with depression and mild cognitive impairment.MethodsA PubMed database search using as keywords “late life depression”, “depression”; “cognitive impairment”; “mild cognitive impairment” and “dementia” between the year 2008 and 2015.ResultsLate-life depression and cognitive impairment are frequent among the elderly (10–20%). Depression is also common in the early stages of dementia decreasing as the cognitive decline progresses. The causal relationship between these entities is not well understood and some authors advocate a multifactorial model (genetic risk factors; neuroendocrine changes; vascular risk factors) and the cognitive impairment of said changes is dependent on the individual's cognitive reserve. Regarding treatment of depression in patients with cognitive impairment, most authors advocate a stepped approach with watchful waiting and then, if symptoms persist, the introduction of pharmacotherapy and psychosocial intervention.ConclusionsThe relationship between cognitive impairment and depression is still not clear and probably multifactorial. The diagnosis of depressive symptoms in patients with severe cognitive impairment can be difficult and most forms of pharmacological treatment in this population are not beneficial, making it important to carefully evaluate the benefits of introducing new medication.Disclosure of interestThe authors have not supplied their declaration of competing interest.


SAGE Open ◽  
2019 ◽  
Vol 9 (3) ◽  
pp. 215824401987913 ◽  
Author(s):  
Rong Fu

The burden of dementia in China is expected to increase dramatically. This study aimed to estimate the potential impact of early parental death on cognitive functioning in late life and whether education is a possible mechanism underlying this association. Data were derived from the 2002 and 2005 waves of the Chinese Longitudinal Healthy Longevity Survey. The final sample consisted of 10,953 Chinese older adults aged 80 to 105 years. Logistic regression models were used to estimate the impact of early parental death and education on the odds of severe cognitive impairment in older men and women. Results showed that experiencing the death of a mother at or before 16 years of age significantly increased the risk of severe cognitive impairment in older men (but not women), independent of demographic, socioeconomic, and physical health conditions. This association did not persist over a 3-year follow-up period and was not mediated by education. These findings provide further evidence that childhood trauma is associated with adverse adult health outcomes, in this case the death of a mother in early life and cognitive impairment in late life. Potential mechanisms that may link early parental death to worse cognitive functioning over the life course were discussed.


Author(s):  
Fabian Fußer ◽  
Tarik Karakaya ◽  
Johannes Pantel

Depression is one of the most prevalent mental diseases in late life, and is a tremendous burden on patients, their families and carers, and the healthcare system. Late-life depression (LLD) often affects people with chronic somatic illnesses, cognitive impairment, and disability. In the elderly, core symptoms of depression are much less pronounced. Instead, unspecific somatic complaints and cognitive impairment may dominate the clinical presentation, and a significant proportion of individuals with LLD goes undiagnosed. This may lead to increased mortality rates, in part attributed to the deleterious consequences of LLD on comorbid somatic illnesses or increased suicide rates. In order to improve prognosis, general practitioners in primary care settings have a prominent but challenging role in recognizing LLD. The diagnostic challenge also includes the differential diagnosis between depression, dementia, and delirium. The optimal management of LLD may include antidepressant drugs, non-pharmacological interventions such as psychotherapy (e.g. cognitive-behavioural therapy), as well as physical exercise.


2004 ◽  
Vol 4 (2) ◽  
pp. 45-50
Author(s):  
Jasminka Hadžihalilović ◽  
Amira Redžić ◽  
Rifat Terzić ◽  
Fatima Jusupović ◽  
Amir Hadžihalilović ◽  
...  

Birth order and its effect on growth and development of children and youths have rarely been studied so far. The objective of this research was an analysis of the birth order effects on some anthropometric properties of the boys 11-16 years old. The sample consisted of 748 boysfrom the Tuzla region. As the sample included very few boys born as the third, forth, or fifth child, we decided to consider only the differences in the mean values for some anthropometric parameters between the groups of the first- and the second-born. Measurements were taken according to IBP and the following parameters were investigated: body height, body mass, chest circumference, upper arm circumference, upper leg circumference, sitting height, arm length, leg length, pelvis width, shoulders width, length and width of head. We established that in most generations the firstborn boys have larger mean values for most anthropometric variables in comparison to the second-born.


Author(s):  
Hye-Jin Kim ◽  
Jin-Young Min ◽  
Kyoung-Bok Min

The association between longest-held lifetime occupation and late-life cognitive impairment: Korean Longitudinal Study of Aging (2006–2016). Backgrounds: Our study hypothesized that occupation in adulthood may be one of the modifiable factors in cognitive performance. This follow-up study aimed to examine whether there was an association between the longest-held occupation in a lifetime and cognitive impairment. Methods: This study used data from the 2006, 2012, and 2016 waves of the Korean Longitudinal Study of Aging, and a total of 1733 subjects aged over 65 were included. Longest-held occupation in a lifetime was classified into blue-collar, pink-collar, and white-collar. Cognitive function was evaluated using the Korean version of the Mini-Mental State Examination. Results: In males, no significant associations were observed. In females, on the contrary, risk of cognitive impairment in the blue-collar occupation was consistently higher than in the white-collar occupation over the 10-year follow-up (2006, OR = 2.49, 95% CI 1.05–5.88; 2016, OR = 2.17, 95% CI 1.02−4.65). Conclusions: Lifetime occupation should be taken into consideration in the process of screening for cognitive decline in the elderly, especially females. This study needs to be interpreted cautiously in view of inherent data and methodological limitations.


2015 ◽  
Vol 11 (7S_Part_8) ◽  
pp. P362-P363 ◽  
Author(s):  
Lon R. White ◽  
Alexander Vostrov ◽  
Chris Zarow ◽  
Joshua Sonnen ◽  
Jane Uyehara-Lock ◽  
...  

2009 ◽  
Vol 24 (S1) ◽  
pp. 1-1
Author(s):  
C. Forlani ◽  
A.R. Atti ◽  
B. Ferrari ◽  
E. Dalmonte ◽  
D. De Ronchi

Aim:To evaluate the relationship between depression, somatic symptoms, cognitive impairment and disability in an elderly population.Methods:216 subjects (65-84 years) were clinically examined for somatic symptoms, and underwent a mental health examination. Depression was defined by Geriatric Depression Scale scores >11/30; cognitive impairment by Mini-Mental State Examination scores < 24/30; functional status by Instrumental Activities of Daily Living Scale. Associations between depression, cognitive impairment or somatic symptoms and disability were evaluated by logistic regression analyses, estimating Odds Ratios (ORs) and 95% confidence intervals (95%CI) adjusted by sex, age, education.Results:Disability was common among depressed individuals (OR(95%CI)=3.60(1.63-7.96)) and among cognitively impaired subjects (OR(95%CI)=7.35(3.07-17.60)). An increasing number of somatic complaints increased the probability of functional impairment: compared with presence of 1-2 somatic symptoms, complaint of 3-6 and 7-12 symptoms were related to disability with OR(95%CI)=3.30(1.11-9.80) and OR (95%CI)=4.20 (1.17-15.09) respectively. Distinguishing pain, gastrointestinal, pseudo-neurological and general symptoms, only general somatic symptoms (palpitations, fatigue, sleep disturbances) were associated with disability (OR(95%CI)=1.81(1.25-2.62), independently by medical conditions (OR(95%CI)=1.57(0.98-2.52)). An additive effect toward disability was observed when general somatic complaints and cognitive impairment were co-existing (OR(95%CI)=23.68(5.50-101.86)). Including simultaneously cognitive impairment, somatic complaints and depression in the model, only cognitive impairment was still significantly related (OR(95%CI)=5.87(2.66-12.96)).Conclusions:Among many possible causes of disability in the elderly, an important role could be attributed to cognitive deficits.


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