Determinants of Postpartum Vitamin D Status in the Caucasian Mother-Offspring Pairs at a Latitude of 52°N: A Cross-Sectional Study

2015 ◽  
Vol 67 (1) ◽  
pp. 33-41 ◽  
Author(s):  
Justyna Czech-Kowalska ◽  
Dariusz Gruszfeld ◽  
Maciej Jaworski ◽  
Dorota Bulsiewicz ◽  
Julita Latka-Grot ◽  
...  
Keyword(s):  
Vitamin D ◽  
Cord Blood ◽  
Sun Exposure ◽  
Maternal Blood ◽  
Cross Sectional Study ◽  
Lower Percentage ◽  
Season Of Birth ◽  
Vitamin D Status ◽  
Cross Sectional ◽  
Vitamin D Intake

Background: High prevalence of vitamin D deficiency in pregnancy is recorded. Aim: To establish determinants of postpartum 25-hydroxyvitamin D (25(OH)D) levels on mothers and offspring. Methods: 25(OH)D level was measured in cord blood and maternal blood collected ≤3 weeks postpartum. Maternal socioeconomic status, vitamin D intake, sun exposure during pregnancy and maternal and neonatal fat mass (FM; dual X-ray absorptiometry) were assessed within 3 weeks postpartum. Results: A total of 174 mother-offspring pairs were enrolled. Maternal 25(OH)D <20 ng/ml was seen in 32 (51%) of summer and 82 (74%) of winter deliveries. Women with 25(OH)D <20 ng/ml had a 2-fold lower percentage of vitamin D intake of ≥800 IU/day than women with 25(OH)D ≥20 ng/ml (p = 0.02). FM (%) was comparable between groups (p > 0.05). Multiple regression analysis revealed the delivery season, prenatal vitamin D intake ≥800 IU/day and duration of supplementation to be the determinants of maternal 25(OH)D level (R2 = 0.26, p < 0.001). Maternal 25(OH)D level, season of birth and duration of maternal supplementation explained 83% of the variance in cord blood 25(OH)D level (R2 = 0.83, p < 0.001). Conclusions: The key determinants of higher maternal vitamin D status were the summer-autumn season of delivery and prenatal use of ≥800 IU/day of vitamin D. The cord blood 25(OH)D level was mainly determined by maternal 25(OH)D level and season of birth.

scholarly journals Vitamin D status in pre-school children in rural Nepal

2015 ◽  
Vol 19 (3) ◽  
pp. 470-476 ◽  
Author(s):  
Diana Avagyan ◽  
Sudan Prasad Neupane ◽  
Thomas E Gundersen ◽  
Ahmed A Madar
Keyword(s):  
Vitamin D ◽  
School Children ◽  
Sun Exposure ◽  
Hypovitaminosis D ◽  
Sociodemographic Factors ◽  
Cross Sectional Study ◽  
Healthy Children ◽  
Vitamin D Status ◽  
Cross Sectional ◽  
Rural Nepal

AbstractObjectiveVitamin D plays a major role in Ca and bone metabolism, and its extraskeletal functions are being appraised. Although inadequate vitamin D concentrations have been reported in populations worldwide, too little is known about vitamin D status and its determinants among children in developing countries. We aimed to determine vitamin D status and its determinants in Nepalese children of pre-school age.DesignA community-based, cross-sectional study.SettingRural Nepal at latitude 27·39°N.SubjectsHealthy children (n280) aged 12–60 months, selected randomly from the records of a vitamin A supplementation programme. Blood samples were collected using the dried blood spot technique and analysed for serum 25-hydroxyvitamin D (s-25(OH)D) concentration using liquid chromatography–tandem mass spectrometry. Ca intake and background variables were assessed with a structured questionnaire.ResultsHypovitaminosis D, defined as s-25(OH)D concentration less than 50 nmol/l, was found in 91·1 % of the children. S-25(OH)D concentration was not related to gender, socio-economic indicators, sun exposure or nutritional status. Currently breast-fed children had higher s-25(OH)D concentrations (36·4 (sd13·2) nmol/l) than those who were not (28·6 (sd9·8) nmol/l,P<0·001). Adjustment for sociodemographic factors did not alter the results.ConclusionThere is widespread vitamin D deficiency among pre-school children in a rural area of Nepal. In our sample, sociodemographic factors did not affect the vitamin D status of children, but prolonged breast-feeding was associated with higher s-25(OH)D concentrations. Further research is required to investigate the health consequences of poor vitamin D status for this population.

scholarly journals Cross-sectional study of factors that influence the 25-hydroxyvitamin D status in pregnant women and in cord blood in Germany

2013 ◽  
Vol 110 (10) ◽  
pp. 1895-1902 ◽  
Author(s):  
Catrin Wuertz ◽  
Peter Gilbert ◽  
Wolfgang Baier ◽  
Clemens Kunz
Keyword(s):  
Vitamin D ◽  
Cord Blood ◽  
Pregnant Women ◽  
Vitamin D Deficiency ◽  
Maternal Blood ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Blood Samples ◽  
Hydroxyvitamin D ◽  
25 Hydroxyvitamin D

There is increasing evidence of an association between a low maternal vitamin D status and a high risk of adverse pregnancy outcomes. In a cross-sectional study, we investigated the vitamin D status of pregnant women to determine potentially influencing factors. Between December 2010 and February 2012, 261 maternal blood samples and 328 cord blood samples were collected for the analysis of 25-hydroxyvitamin D (25(OH)D), intact parathyroid hormone, alkaline phosphatase and Ca concentrations. Demographical characteristics and clinical data were recorded by a questionnaire and from medical files. The overall median maternal and cord blood 25(OH)D levels were 25·0 (interquartile range 12·6–45·5) nmol/l and 34·1 (interquartile range 17·7–58·6) nmol/l, respectively. During the winter months, 98 % of the maternal blood samples and 94 % of the cord blood samples had 25(OH)D levels < 50 nmol/l. In the summer months, 49 % of the women and 35 % of the cord blood samples were vitamin D deficient. Using logistic regression models, significant risk factors for maternal vitamin D deficiency were found to be physical inactivity (adjusted OR (aOR) 2·67, 95 % CI 1·06, 6·69, P= 0·032) and a non-European country of origin (aOR 3·21, 95 % CI 1·0, 10·28, P= 0·047) after controlling for season and independent risk factors. These results are the first 25(OH)D data for pregnant women in Germany. They indicate the need for urgent implementation of strategies to prevent vitamin D deficiency by healthcare authorities that are in charge of preventing vitamin D deficiency, especially during these sensitive stages of life.

scholarly journals Effects of occupational sunlight exposure and monsoon season on vitamin D concentration among outdoor and indoor workers in Malaysia

2020 ◽  
Vol 26 (3) ◽  
pp. 425-439
Author(s):  
Norliyana Aris ◽  
◽  
Amal K. Mitra ◽  
Wan Mohd Izani Wan Mohamed ◽  
Wan Abdul Manan Wan Muda ◽  
...  
Keyword(s):  
Vitamin D ◽  
Monsoon Season ◽  
Sun Exposure ◽  
Cross Sectional Study ◽  
Sunlight Exposure ◽  
Activity Level ◽  
Northeast Monsoon ◽  
Vitamin D Status ◽  
Cross Sectional ◽  
Endocrine Society

Introduction: Despite abundant sunshine for cutaneous vitamin D synthesis, low levels of vitamin D have been documented among the Malaysian population. The aim of this study was to characterise the effects of occupational sunlight exposure and monsoon season on serum 25-hydroxyvitamin D [25(OH)D] concentration. Methods: A comparative cross-sectional study was performed among Malay outdoor (n=119) and indoor workers (n=119) in Kelantan. Two-point data were collected on the same participants, first during non-monsoon season and second during the northeast monsoon season. Data collection comprised of anthropometry measurements (body mass index and body fat), fasting blood test [serum 25(OH)D concentration], and questionnaire (physical activity level, sun exposure, sun protection use, and vitamin D intake). Vitamin D classification was based on the 2011 Endocrine Society Clinical Practice Guidelines. Results: This study found that serum 25(OH)D concentrations were significantly higher in outdoor compared to indoor workers irrespective of season (p<0.001) and sex (p<0.001). Monsoonal differences in serum 25(OH)D concentration was only observed in male outdoor workers (mean difference=10.39 nmol/l, p<0.001). Significant association between vitamin D status and occupation was also observed (p<0.001). However, no significant association was found between vitamin D status and monsoon season [χ2(1)=0.076, p=0.783]. Conclusion: Seasonal and occupational factors should be considered while evaluating individual serum 25(OH)D concentration and in comparing community studies, especially among workers.

scholarly journals Age and Spinal Disease Correlate to Albumin and Vitamin D Status

2021 ◽  
pp. 219256822098256
Author(s):  
Anderson Gomes Marin ◽  
Raphael de Rezende Pratali ◽  
Samuel Machado Marin ◽  
Carlos Fernando Pereira da Silva Herrero
Keyword(s):  
Vitamin D ◽  
Nutritional Status ◽  
Age Groups ◽  
Hypovitaminosis D ◽  
Cross Sectional Study ◽  
Surgical Approaches ◽  
Albumin Concentration ◽  
Vitamin D Status ◽  
Cross Sectional ◽  
Epidemiological Profile

Study Design: Cross-sectional study. Objectives: Thus, this study aimed to assess the epidemiological profile of a patient sample that underwent spinal surgery regarding their nutritional and vitamin D status. Methods: Serum albumin and vitamin D (25-hydroxyvitamin D) levels were measured in patients with different spinal surgical approaches and various pathologies at a single institution. 112 patients were retrospectively identified for inclusion and stratified by age into 4 age groups and by pathology. The nutritional status of the patients was classified in vitamin D inadequacy (< 30ng/mL), vitamin D deficiency (<20ng/mL), and hypoalbuminemia (<3.5g/dL). Data was analyzed comparing vitamin D, and albumin means considering gender, age group, and pathologies. Results: Twenty-eight (25.2%) patients had hypoalbuminemia. There was no difference between gender (p = 0.988); there was a significant decrease in albumin concentration increasing the age (p < 0.001). The prevalence of hypoalbuminemia was significantly higher in patients with trauma, tumor and infection than in those patients with degenerative and deformity diseases (p = 0.003). The prevalence of vitamin D inadequacy was 33.7%, and that of deficiency was 62.2%, while severe deficiency (< 10 ng/mL) in 16.3%. The vitamin D concentration was significantly different among the pathologies (P = 0.047), the lower concentration occurring in patients with tumor. Conclusion: Older patients, as well as patients with tumor and infectious pathologies, seem to have a higher prevalence of hypoalbuminemia, inferring malnutrition. There was a low epidemic level of vitamin D concentration, almost all patients presenting some degree of hypovitaminosis D, independent of age, gender and nutritional status.

scholarly journals Vitamin D status and associated metabolic risk factors among North Korean refugees in South Korea: a cross-sectional study

BMJ Open ◽  
2015 ◽  
Vol 5 (11) ◽  
pp. e009140 ◽  
Author(s):  
Kyeong Jin Kim ◽  
Yoon Jung Kim ◽  
Sun Hwa Kim ◽  
Jee Hyun An ◽  
Hye Jin Yoo ◽  
...  
Keyword(s):  
Risk Factors ◽  
Vitamin D ◽  
South Korea ◽  
Cross Sectional Study ◽  
Metabolic Risk Factors ◽  
Metabolic Risk ◽  
Vitamin D Status ◽  
Sectional Study ◽  
Cross Sectional ◽  
North Korean Refugees

scholarly journals Cross-sectional study reveals a high prevalence of vitamin D deficiency among healthy school children in central Kerala, India

2019 ◽  
Vol 6 (2) ◽  
pp. 867
Author(s):  
Ayyappan Anitha ◽  
Suresh A. Poovathinal ◽  
Vijitha Viswambharan ◽  
Ismail Thanseem ◽  
Mahesh M. Vasu ◽  
...  
Keyword(s):  
Vitamin D ◽  
School Children ◽  
Skin Color ◽  
Economic Status ◽  
Cross Sectional Study ◽  
Vitamin D Status ◽  
Sectional Study ◽  
Cross Sectional ◽  
Vitamin D Levels ◽  
High Prevalence

Background: Authors examined serum vitamin D status among the healthy school children belonging to the south Indian state of Kerala.Methods: A cross-sectional study, participants were recruited through medical camps organized in Thrissur and Palakkad districts of central Kerala during the months of March and April 2017. A 174 healthy school children (98 males and 76 females) aged 5-13 years were recruited for the study. The children were found to be healthy on the basis of physical examination by a Paediatrician. None of the children had any symptoms of skeletal deformities. All the children were drug-naive. Data on height, weight, skin color, food habits, physical activities and socio-economic status were recorded. A 2ml of peripheral blood samples were collected from the participants. Total vitamin D in the serum was estimated by chemiluminescence immunoassay (CLIA).Results: VDD was observed in 60.92% and insufficiency in 30.46% of the participants. Only 8.62% of the participants had normal vitamin D levels. The mean vitamin D level was 19.93 ng/ml. Males had significantly higher vitamin D levels compared to females. Factors such as age, height, weight, diet, skin color and socio-economic status did not influence vitamin D levels.Conclusions: This is the first study of vitamin D status among the school-age children of Kerala. This paper adds further evidence to the reports indicating high prevalence of subclinical VDD among children across India and calls for action.

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