scholarly journals Potentially Inappropriate Prescribing in Disabled Older Patients with Chronic Diseases: A Screening Tool of Older Persons' Potentially Inappropriate Prescriptions versus Beers 2012 Criteria

2015 ◽  
Vol 24 (6) ◽  
pp. 565-570 ◽  
Author(s):  
Po-Jen Yang ◽  
Yuan-Ti Lee ◽  
Shu-Ling Tzeng ◽  
Huei-Chao Lee ◽  
Chin-Feng Tsai ◽  
...  
Keyword(s):  
Chronic Diseases ◽  
Older Patients ◽  
Older Persons ◽  
Screening Tool ◽  
Inappropriate Prescribing ◽  
Potentially Inappropriate Prescribing ◽  
Inappropriate Prescriptions

scholarly journals Multimorbidity patterns in chronic older patients, potentially inappropriate prescribing and adverse drug reactions: protocol of the multicentre prospective cohort study MoPIM

BMJ Open ◽  
2020 ◽  
Vol 10 (1) ◽  
pp. e033322
Author(s):  
Marisa Baré ◽  
Susana Herranz ◽  
Rosa Jordana ◽  
Maria Queralt Gorgas ◽  
Sara Ortonobes ◽  
...  
Keyword(s):  
Cohort Study ◽  
Adverse Drug Reactions ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Older Patients ◽  
Screening Tool ◽  
Inappropriate Prescribing ◽  
Fatal Outcome ◽  
Potentially Inappropriate Prescribing ◽  
Drug Reactions

IntroductionMultimorbidity is a major challenge for current healthcare systems and professionals. From the different approaches that have been proposed to analyse this issue, the hypothesis of the existence of association patterns of different chronic conditions is gaining visibility. In addition, multimorbidity can be associated to polypharmacy, which can lead to a higher risk of potentially inappropriate prescribing (PIP) and consequently to adverse drug reactions (ADRs). The general objective of this novel study is to identify the association between PIP, multimorbidity patterns, polypharmacy and the presence of ADRs in older patients admitted for exacerbation of chronic diseases.Methods and analysisThe MoPIM (morbidity, potentially inappropriate medication) study is a multicentre prospective cohort study of an estimated sample of 800 older (≥65 years) patients admitted to five general hospitals in Spain due to an exacerbation of a chronic disease. Patients referred to home hospitalisation, admitted due to an acute process or with a fatal outcome expected at the time of admission are excluded. Sociodemographic data, chronic morbidities and geriatric syndromes, number of chronic prescribed medications, PIP at admission to hospital and on discharge, according to the newest screening tool of older screening tool of older person's potentially inappropriate prescriptions/screening tool to alert doctors to right treatment criteria, and ADRs during hospitalisation are being collected. Multimorbidity patterns will be identified using cluster analyses techniques, and the frequency of polypharmacy, PIP and ADRs will be calculated. Finally, the possible relationship between those indicators will be identified through bivariate and multivariate analyses.Ethics and disseminationThe project has been approved by the clinical research ethics committees of each centre: Comité Ético de investigación Clínica del Parc Taulí, Comitè Ètic d'Investigació Clínica Osona per a la Recerca i Educació Sanitàries (FORES), Comité de Ètica de la Investigación con Medicamentos (CEIm)-Parc de Salut MAR, Comité Ético de Investigación Clínica de Euskadi, Comité de Ética de Investigación del Hospital Universitario de Canarias. The results will be actively and mainly disseminated through publication in peer-reviewed journals and communications in scientific conferences.Trial registration numberNCT02830425.

Risk factors for potentially inappropriate prescribing to older patients in primary care

2015 ◽  
Vol 72 (1) ◽  
pp. 93-107 ◽  
Author(s):  
Ivana Projovic ◽  
Dubravka Vukadinovic ◽  
Olivera Milovanovic ◽  
Milena Jurisevic ◽  
Radisa Pavlovic ◽  
...  
Keyword(s):  
Risk Factors ◽  
Primary Care ◽  
Older Patients ◽  
Inappropriate Prescribing ◽  
Potentially Inappropriate Prescribing

Detection of potentially inappropriate prescribing in older patients with the GheOP³S-tool: completeness and clinical relevance

2019 ◽  
Vol 74 (2) ◽  
pp. 126-136 ◽  
Author(s):  
C. Kympers ◽  
E. Tommelein ◽  
Ellen Van Leeuwen ◽  
K. Boussery ◽  
M. Petrovic ◽  
...  
Keyword(s):  
Clinical Relevance ◽  
Older Patients ◽  
Inappropriate Prescribing ◽  
Potentially Inappropriate Prescribing

scholarly journals Potentially inappropriate prescribing in older hospitalized Dutch patients according to the STOPP/START criteria v2: a longitudinal study

2020 ◽  
Author(s):  
Birgit A. Damoiseaux-Volman ◽  
Stephanie Medlock ◽  
Kimmy Raven ◽  
Danielle Sent ◽  
Johannes A. Romijn ◽  
...  
Keyword(s):  
Longitudinal Study ◽  
Older Patients ◽  
Hospital Admissions ◽  
Inappropriate Medication ◽  
Inappropriate Prescribing ◽  
Patient Characteristics ◽  
Start Criteria ◽  
High Prevalence ◽  
Inappropriate Prescriptions ◽  
Over Time

Abstract Purpose To investigate prevalence, independent associations, and variation over time of potentially inappropriate prescriptions in a population of older hospitalized patients. Methods A longitudinal study using a large dataset of hospital admissions of older patients (≥ 70 years) based on an electronic health records cohort including data from 2015 to 2019. Potentially inappropriate medication (PIM) and potential prescribing omission (PPO) prevalence during hospital stay were identified based on the Dutch STOPP/START criteria v2. Univariate and multivariate logistic regression were used for analyzing associations and trends over time. Results The data included 16,687 admissions. Of all admissions, 56% had ≥ 1 PIM and 58% had ≥ 1 PPO. Gender, age, number of medications, number of diagnoses, Charlson score, and length of stay were independently associated with both PIMs and PPOs. Additionally, number of departments and number of prescribing specialties were independently associated with PIMs. Over the years, the PIM prevalence did not change (OR = 1.00, p = .95), whereas PPO prevalence increased (OR = 1.08, p < .001). However, when corrected for changes in patient characteristics such as number of diagnoses, the PIM (aOR = 0.91, p < .001) and PPO prevalence (aOR = 0.94, p < .001) decreased over the years. Conclusion We found potentially inappropriate prescriptions in the majority of admissions of older patients. Prescribing relatively improved over time when considering complexity of the admissions. Nevertheless, the high prevalence shows a clear need to better address this issue in clinical practice. Studies seeking effective (re)prescribing interventions are warranted.

scholarly journals The Association Between Potentially Inappropriate Prescribing and Medication-Related Hospital Admissions in Older Patients: A Nested Case Control Study

Drug Safety ◽  
2015 ◽  
Vol 39 (1) ◽  
pp. 79-87 ◽  
Author(s):  
C. A. K. van der Stelt ◽  
A. M. A. Vermeulen Windsant-van den Tweel ◽  
A. C. G. Egberts ◽  
P. M. L. A. van den Bemt ◽  
A. J. Leendertse ◽  
...  
Keyword(s):  
Older Patients ◽  
Case Control Study ◽  
Hospital Admissions ◽  
Inappropriate Prescribing ◽  
Case Control ◽  
Potentially Inappropriate Prescribing ◽  
Nested Case Control ◽  
Control Study
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