scholarly journals Free-Floating Iris Cyst in a Patient with Recurrent Iritis

2015 ◽  
Vol 6 (2) ◽  
pp. 176-179 ◽  
Author(s):  
Joanne M.Y. Teong ◽  
Paul A. Adler ◽  
Dujon R.W. Fuzzard
Keyword(s):  
Anterior Chamber ◽  
Clinical Finding ◽  
Surgical Removal ◽  
Slit Lamp ◽  
Visual Symptoms ◽  
History Of ◽  
Iris Cyst

Purpose: We describe an unusual clinical finding of a free-floating iris cyst in a patient with recurrent iritis. Method: The clinical finding of a free-floating iris cyst was recorded using slit-lamp photography. Results: A 39-year-old male with a 5-year history of recurrent right iritis was found to have a small mobile iris cyst within his right anterior chamber, first identified 3 years ago. The patient did not experience any discomfort or visual symptoms resulting from the cyst. Conclusion: Surgical removal is not indicated for asymptomatic non-progressive free-floating iris cysts. The significance of a free-floating iris cyst in the setting of recurrent iritis remains unknown.

scholarly journals Implantation epithelial iris cyst following the perforating corneal injury

2006 ◽  
Vol 134 (3-4) ◽  
pp. 151-154
Author(s):  
Milos Jovanovic ◽  
Zoran Latkovic
Keyword(s):  
Visual Acuity ◽  
Anterior Chamber ◽  
Cataract Extraction ◽  
Wound Management ◽  
Surgical Removal ◽  
Extracapsular Cataract Extraction ◽  
Secondary Cataract ◽  
Corneal Injury ◽  
Iris Cyst ◽  
Iris Prolapse

The objective of this case report was to present the development of implantation cyst following the perforating corneal injury, the problems related to the treatment, including total surgical excision of the cyst, the secondary cataract extraction, iridoplasty and the artificial intraocular lens reposition. A patient first presented with perforating corneal injury inflicted by a piece of wood, with the iris prolapse. Primary wound management, reposition of prolapsed iris and corneal sutures were performed four days after the injury. Eight months later, the patient was rehospitalized due to an implantation iris cyst and traumatic cataract. The cyst was excised, the extracapsular cataract extraction was done and the anterior chamber lens was implanted. Postoperative visual acuity was normal. Three years later, the patient presented for a follow-up examination, with the cyst filled up again, occupying two thirds of the anterior chamber. This time, the cyst was completely excised, all fibrous remnants of the secondary cataract were removed, and the iridoplasty was necessary due to large iris coloboma. Reposition of the anterior chamber lens was carried out. Histological examination revealed an implantation iris cyst covered by multilayered squamous epithelium. Normal visual acuity was achieved. The patient has been followed-up for six months uneventfully. Management of perforating corneal wound with iris prolapse may lead to development of an implantation iris cyst. Puncture of the cyst as well as incomplete excision will not solve the problem. Complete surgical removal of the iris cyst is the treatment of choice.

scholarly journals Surgical removal of a free-floating iris cyst in anterior chamber in a Han Chinese man

2014 ◽  
Vol 93 (6) ◽  
pp. e514-e515
Author(s):  
Xu-yuan Tang ◽  
Wei Han ◽  
Hong-guang Cui ◽  
Rong-rong Hu ◽  
Jian-yong Wang ◽  
...  
Keyword(s):  
Anterior Chamber ◽  
Han Chinese ◽  
Surgical Removal ◽  
Iris Cyst

scholarly journals Free-Floating Iris Pigmented Epithelial Cyst in the Anterior Chamber

2016 ◽  
Vol 2016 ◽  
pp. 1-3 ◽  
Author(s):  
Tryfon Rotsos ◽  
Georgios Bagikos ◽  
Spyridon Christou ◽  
Chrysanthos Symeonidis ◽  
Thekla Papadaki ◽  
...  
Keyword(s):  
Anterior Chamber ◽  
Unusual Case ◽  
Ultrasound Biomicroscopy ◽  
Visual Disturbance ◽  
Thin Wall ◽  
Slit Lamp ◽  
Epithelial Cyst ◽  
Visual Defect ◽  
The Past ◽  
Iris Cyst

An unusual case of a free-floating peripheral pigmented cyst in the anterior chamber is presented. A 30-year-old Caucasian male presented reporting a visual defect on his right eye in prone position over the past year. Slit-lamp examination revealed a small pigmented free-floating peripheral iris cyst at the 6 o’clock position in the anterior chamber. Ultrasound biomicroscopy revealed an unfixed epithelial pigmented cyst with an extremely thin wall and no internal reflectivity. Due to the lack of severity of visual disturbance of the patient, no surgical treatment was indicated. The patient is to be followed up annually and advised to return immediately in case of pain or any visual symptoms. Free-floating iris cysts in the anterior chamber are uncommon and remain stable in the majority of cases. Management includes only regular observation until any complications arise.

scholarly journals Machine Learning-Guided Prediction of Central Anterior Chamber Depth Using Slit Lamp Images from a Portable Smartphone Device

Biosensors ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 182
Author(s):  
David Chen ◽  
Yvonne Ho ◽  
Yuki Sasa ◽  
Jieying Lee ◽  
Ching Chiuan Yen ◽  
...  
Keyword(s):  
Machine Learning ◽  
Anterior Chamber ◽  
Anterior Segment ◽  
Anterior Chamber Depth ◽  
Training Data ◽  
Portable Devices ◽  
Anatomical Landmarks ◽  
Strong Positive Correlation ◽  
Slit Lamp ◽  
History Of

There is currently no objective portable screening modality for narrow angles in the community. In this prospective, single-centre image validation study, we used machine learning on slit lamp images taken with a portable smartphone device (MIDAS) to predict the central anterior chamber depth (ACD) of phakic patients with undilated pupils. Patients 60 years or older with no history of laser or intraocular surgery were recruited. Slit lamp images were taken with MIDAS, followed by anterior segment optical coherence tomography (ASOCT; Casia SS-1000, Tomey, Nagoya, Japan). After manual annotation of the anatomical landmarks of the slit lamp photos, machine learning was applied after image processing and feature extraction to predict the ACD. These values were then compared with those acquired from the ASOCT. Sixty-six eyes (right = 39, 59.1%) were included for analysis. The predicted ACD values formed a strong positive correlation with the measured ACD values from ASOCT (R2 = 0.91 for training data and R2 = 0.73 for test data). This study suggests the possibility of estimating central ACD using slit lamp images taken from portable devices.

Pathological Findings of Synchysis Scintillans Secondary to Familial Exudative Vitreoretinopathy With Chronic Exudative Retinal Detachment

2019 ◽  
Vol 4 (2) ◽  
pp. 163-166
Author(s):  
James Lin ◽  
Armando Garcia ◽  
Ying Chen ◽  
Sander Dubovy ◽  
Wendy Lee ◽  
...  
Keyword(s):  
Retinal Detachment ◽  
Anterior Chamber ◽  
Vitreous Hemorrhage ◽  
Exudative Retinal Detachment ◽  
Slit Lamp ◽  
Pathological Findings ◽  
Unique Case ◽  
Familial Exudative Vitreoretinopathy ◽  
Pathological Correlation ◽  
History Of

Purpose: We describe a unique case of synchysis scintillans in a 23-year-old woman with a history of chronic exudative retinal detachment in the setting of familial exudative vitreoretinopathy. Methods: Fundus and slit-lamp photographs were obtained at presentation, and pathological studies were performed on the enucleated specimen to confirm the diagnosis. Results: Synchysis scintillans is a degenerative condition of cholesterol deposition that affects severely damaged eyes, often as a result of chronic vitreous hemorrhage or retinal detachment. In this case, synchysis scintillans presented as crystals in the anterior chamber in the setting of a chronic retinal detachment. After enucleation, there were noted to be cholesterol slits on pathological correlation, confirming the diagnosis. Conclusions: This case demonstrates the importance of clinical pathological correlation in the diagnosis of synchysis scintillans migrating into the anterior chamber.

A secondary iris cyst with 3 years of asymptomatic period following a blunt ocular trauma

2020 ◽  
pp. 112067212090170
Author(s):  
Hong-Yang Li ◽  
Mei-Jun Li ◽  
Zhi-Yi Xu ◽  
Jia-Hui Li ◽  
Wen-Lin Zheng ◽  
...  
Keyword(s):  
Anterior Chamber ◽  
Ocular Trauma ◽  
Imaging Techniques ◽  
Anterior Segment ◽  
Head Tilt ◽  
Long Time ◽  
History Of ◽  
Iris Cyst ◽  
Uncommon Case ◽  
Blunt Ocular Trauma

Purpose: To present a relatively uncommon case with a secondary iris cyst in the anterior chamber and its successful management with an anterior chamber mass excision surgery. Case report: A 46-year-old Chinese woman presented with a dark shadow in her left eye for 6 months without any other discomfort. She had a history of blunt ocular trauma by a badminton strike 3 years ago. Slit-lamp examination showed a small, nearly circular, sharply demarcated, and movable mass in the anterior chamber OS, which could change its position with head tilt. The anterior segment optical coherence tomography revealed a well-circumscribed cystic lesion in the anterior chamber with higher reflective outer layer and lower internal reflectivity. An anterior chamber mass removal surgery was performed without recurrence up to 1 year. Conclusion: Secondary free-floating iris cyst following a blunt trauma is rarely reported. It is relatively stable and nonprogressive so it may remain asymptomatic for a long time. Appropriate imaging techniques are necessary for facilitating diagnosis and therapy. Therapeutic management should be considered if visual symptoms arise, especially when complications occur.

scholarly journals Identification of a Novel Missense KRT12 Mutation in a Vietnamese Family with Meesmann Corneal Dystrophy

2020 ◽  
Vol 11 (1) ◽  
pp. 120-126
Author(s):  
Pham Ngoc Dong ◽  
Le Xuan Cung ◽  
Tran Khanh Sam ◽  
Do Thi Thuy Hang ◽  
Doug D. Chung ◽  
...  
Keyword(s):  
Sanger Sequencing ◽  
Novel Mutation ◽  
Family Members ◽  
Corneal Dystrophy ◽  
Slit Lamp ◽  
Slit Lamp Examination ◽  
Corneal Epithelial ◽  
Epithelial Phenotype ◽  
History Of ◽  
Characteristic Features

Meesmann epithelial corneal dystrophy (MECD) is a rare dominantly inherited disorder that is characterized by corneal epithelial microcysts and is associated with mutations in the keratin 3 (KRT3) and keratin 12 (KRT12) genes. In this study, we report a novel mutation in the KRT12 gene in a Vietnamese pedigree with MECD. Slit-lamp examination was performed on each of the 7 recruited members of a Vietnamese family to identify characteristic features of MECD. After informed consent was obtained from each individual, genomic DNA was isolated from saliva samples and screening of KRT3and KRT12 genes was performed by Sanger sequencing. The proband, a 31-year-old man, complained of a 1-year history of eye irritation and photophobia. Slit-lamp examination revealed intraepithelial microcysts involving only the corneal periphery in each eye with clear central corneas and no stromal or endothelial involvement. Three family members demonstrated similar intraepithelial microcysts, but with diffuse involvement, extended from limbus to limbus. Sanger sequencing of KRT3 (exon 7) and KRT12 (exons 1 and 6) in the proband revealed a novel heterozygous KRT12 variant (c.1273G>A [p.Glu425Lys]) that was present in the three affected family members but was absent in the three family members with clear corneas. This study is the first report of a Vietnamese family affected with MECD, associated with an atypical peripheral corneal epithelial phenotype in the proband and a novel mutation in KRT12.

Ahmed glaucoma valve in vitrectomized eyes: An implantation technique to minimize early postoperative fluid-loss hypotony

2021 ◽  
pp. 112067212110122
Author(s):  
Paolo Arpa ◽  
Cristina Arpa
Keyword(s):  
Surgical Technique ◽  
Anterior Chamber ◽  
Previous History ◽  
Implantation Technique ◽  
Fluid Loss ◽  
Ahmed Glaucoma Valve ◽  
Intraocular Hemorrhage ◽  
Hemorrhagic Complications ◽  
History Of ◽  
Choroidal Effusion

Purpose: To describe the application of a modified Ahmed glaucoma valve (AGV) surgical implantation technique in vitrectomized eyes, in order to minimize the risk of early postoperative hypotony, which leads to hemorrhagic complications. Materials and methods: Data of patients implanted with AGV using the surgical technique described were retrospectively reviewed. Inclusion criterion: glaucomatous eyes with previous history of pars plana vitrectomy. Intraocular pressure (IOP) measurement and ophthalmic examination were performed preoperatively and postoperatively weekly for 1 month for the detection of early hypotony, choroidal effusion/detachment, intraocular hemorrhage. The surgical technique consisted in creating a 5 mm long scleral tunnel with a 23 G needle reaching the anterior chamber at the iridocorneal angle, in which the Ahmed glaucoma valve tube was inserted. Results: Ten eyes of 10 patients were included. Median preoperative IOP was 30.5 mmHg [interquartile range (IQR) 28.3–33.0]; median postoperative IOP was 12.0 mmHg (IQR 9.3–13.0) at 1 week, and 12.5 mmHg (IQR 11.0–15.0) at 1 month. In no cases postoperative IOP was <8 mmHg. On the first postoperative day, five (50%) eyes showed few blood clots in the anterior chamber. On the second-week appointment, moderate choroidal effusion was observed in two eyes (20%). No hemorrhagic complications were observed. Conclusions: The creation of a long intrascleral tunnel with a 23 G needle for AGV implantation in vitrectomized eyes could be effective in decreasing leakage through the space between the valve tube and the sclerocorneal tissue. This technique is safe, easy to perform, feasible and fast. Due to its advantages and good postoperative results, it could also be adopted in non-vitrectomized eyes.

Endothelial cell density change in fully dislocated XEN Gel IMPLANT after trabeculectomy: A case report

2021 ◽  
pp. 112067212198963
Author(s):  
Martina Menchini ◽  
Francesco Sartini ◽  
Filippo Tatti ◽  
Enrico Peiretti ◽  
Michele Figus
Keyword(s):  
Endothelial Cell ◽  
Anterior Chamber ◽  
Cell Density ◽  
Cell Loss ◽  
Endothelial Cell Density ◽  
Endothelial Cell Loss ◽  
Density Reduction ◽  
History Of ◽  
Cell Loss Rate

Purpose: To report a case of fully dislocated XEN Gel Implant device into the anterior chamber, 18 months after its implantation and its impact on endothelial cell density. Result: A 75-year-old man with a history of multiple glaucoma surgeries during the last three years presented with an entirely dislocated XEN Gel implant into the anterior chamber. An endothelial cell density reduction was observed over 18 months. Thus, the implant was removed. In the short-term after surgery, the endothelial cell loss rate reduced. Conclusion: XEN Gel Implant can dislocate into the anterior chamber, increasing endothelial cell loss in an eye already underwent multiple surgical procedures with subsequent adverse events. Therefore, if the implant seems displaced, the endothelial cell density should be monitored, and the length of the free-tube segment within the anterior chamber should be measured, during the patient’s follow-up.

Progressive multifocal leukoencephalopathy in a patient with occult hypogammaglobulinemia experiencing bilateral visual impairment

2021 ◽  
pp. 112067212199053
Author(s):  
Sameera Hettipathirannahelage ◽  
Sidath Wijetilleka ◽  
Hugh Jewsbury
Keyword(s):  
Progressive Multifocal Leukoencephalopathy ◽  
Visual Impairment ◽  
Demyelinating Disease ◽  
Parietal Lobe ◽  
Previous History ◽  
White Matter Lesions ◽  
Slit Lamp ◽  
Slit Lamp Examination ◽  
History Of ◽  
Ishihara Test

Introduction: Progressive multifocal leukoencephalopathy (PML) is a rare, lethal, demyelinating disease classically seen in profoundly immunosuppressed individuals. It is caused by intracerebral infection by John Cunningham polyomavirus (JCV). We report a rare case of PML in a man with presumed immunocompetence at presentation experiencing bilateral painless visual impairment. Case Description: A 60-year-old man with a 3-week history of bilateral painless visual impairment attended our ophthalmology department. Unusually, he navigated around the room well and was able to read 4 of 13 Ishihara test plates in spite of a best-corrected visual acuity of counting fingers at 1 m bilaterally. Slit lamp examination, routine blood tests and optical coherence tomography (OCT) of the maculae and discs were unremarkable. Diffuse hyperintense white matter lesions on T2-weighted magnetic resonance imaging of the brain and detection of JCV within the parietal lobe tissue obtained by biopsy confirmed PML. Additional investigations identified an underlying hypogammaglobulinaemia, which may have initiated PML. He received intravenous immunoglobulin but passed away 2 months after diagnosis. Conclusions: To our knowledge this case is one of only a handful worldwide to describe PML developing in a patient with presumed immunocompetence at presentation – there was no previous history of recurrent, chronic, or atypical infections. There has only been one other report of visual symptoms presenting as the primary complaint. The case illustrates the importance of ruling out organic, central nervous system pathology in patients presenting with visual loss and normal objective visual function tests such as slit lamp examination and OCT.

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