scholarly journals Diffuse Dermal Angiomatosis: A Clue to the Diagnosis of Atherosclerotic Vascular Disease

2015 ◽  
Vol 7 (2) ◽  
pp. 100-106 ◽  
Author(s):  
Tueboon Sriphojanart ◽  
Vasanop Vachiramon
Keyword(s):  
Bypass Surgery ◽  
Tight Control ◽  
Atherosclerotic Vascular Disease ◽  
Reticular Dermis ◽  
Heavy Smoking ◽  
Spindle Cells ◽  
Vascular Bypass ◽  
Vascular Proliferation ◽  
Central Ulceration ◽  
The Right

Diffuse dermal angiomatosis (DDA) is a benign, acquired, reactive vascular proliferation. DDA is clinically characterized by painful purpuric plaque with central ulceration. The histopathologic hallmark is diffuse proliferation of endothelial cells that are arranged interstitially between collagen bundles of the reticular dermis. DDA has been reported in association with peripheral atherosclerotic disease, arteriovenous fistula and heavy smoking. We report the case of a 49-year-old Asian male with DDA who presented with a painful stellate-shaped purpuric patch on the right thigh. Histopathologic examination showed proliferation of CD34-positive spindle cells in the dermis. Our patient underwent vascular bypass surgery along with tight control of cardiovascular risk factors, which yielded successful results.

scholarly journals Feasibility study on retinal vascular bypass surgery in isolated arterially perfused caprine eye model

Eye ◽  
2011 ◽  
Vol 25 (11) ◽  
pp. 1499-1503 ◽  
Author(s):  
Y Chen ◽  
W Wu ◽  
X Zhang ◽  
W Fan ◽  
L Shen
Keyword(s):  
Feasibility Study ◽  
Bypass Surgery ◽  
Eye Model ◽  
Vascular Bypass

Angiectatic Nasal Polyps That Clinically Simulate a Malignant Process

2000 ◽  
Vol 124 (3) ◽  
pp. 406-410 ◽  
Author(s):  
Harry G. Yfantis ◽  
Cinthia B. Drachenberg ◽  
William Gray ◽  
John C. Papadimitriou
Keyword(s):  
Electron Microscopy ◽  
Stromal Cells ◽  
Nasal Polyps ◽  
Spindle Cell ◽  
Histologic Diagnosis ◽  
Adult Men ◽  
Spindle Cells ◽  
Vascular Proliferation ◽  
Life Threatening ◽  
Aggressive Clinical Behavior

Abstract Background.—Approximately 5% of inflammatory or allergic sinonasal polyps develop extensive vascular proliferation and ectasia with deposition of pseudoamyloid. These so-called angiectatic nasal polyps (ANPs) can grow rapidly and exhibit an aggressive clinical behavior that could simulate malignancy preoperatively. Objective.—To systematically address the differential histologic diagnosis of ANPs. Methods.—We evaluated by light microscopy, immunohistochemistry, and electron microscopy biopsy and resection specimens from 2 large ANPs (8 and 10 cm in diameter) that presented in 2 adult men with life-threatening epistaxis and facial deformity, respectively. Results.—The tumors were firm, lobulated, and covered by smooth, partially ulcerated mucosa. Histologically, clusters of dilated, thin-walled blood vessels embedded in pools of Congo red–negative eosinophilic material, associated with patchy necrosis and atypical stromal spindle cells, were seen. Electron microscopy and immunohistochemistry (CD34, factor VIII) confirmed the endothelial nature of the cells lining the spaces, whereas the atypical stromal cells were classified as myofibroblasts. Conclusions.—These 2 cases represent extreme examples of ANPs that clinically simulate a malignant process. Awareness of the histological features of ANPs should prevent confusion of such lesions with other vascular or spindle cell lesions of the nasopharynx that would require different treatment and carry a different prognosis.

scholarly journals Seminoma and sertolioma in non-cryptorchid dog – case report

2021 ◽  
Vol 15 (4) ◽  
pp. 281-286
Author(s):  
Guilherme Mantuani Silva ◽  
Isabela Cristina de Oliveira ◽  
Rodrigo Samuel de Toledo ◽  
Juliana Evangelista Bezerril ◽  
Gabriela Maria Benedetti Vasques ◽  
...  
Keyword(s):  
Physical Examination ◽  
Ultrasound Examination ◽  
Histopathological Examination ◽  
Seminiferous Tubules ◽  
Biochemical Tests ◽  
Predisposing Factor ◽  
Left Testicle ◽  
Spindle Cells ◽  
Mixed Breed ◽  
The Right

The most common testicular neoplasms in dogs are seminoma, leydigocytoma and sertolioma, affecting middle--aged and elderly dogs, where cryptorchidism is a predisposing factor, as well as some breeds. It can occur alone or, less fren-quently, concurrently, generally affecting the same testicle. This study aimed to report the case of a non-cryptorchid 14-year--old mixed breed dog diagnosed with seminoma and sertolioma, each in a testicle. The animal showed an increase in scrotal volume, with no changes in other clinical parameters on physical examination. On ultrasound examination, it was possible to observe alterations suggestive of neoplasia in both testicles and prostatic alteration suggestive of benign prostatic hyperplasia. Complementary blood count and biochemical tests were performed and, as treatment, orchiectomy was performed. Fragments were collected from both testicles and sent for histopathological examination. Microscopy of the left testicle showed the presence of round cells, multiple and evident nucleoli, cells in different phases of mitosis and binucleation, these changes being compa-tible with seminoma. In contrast, in the right testicle, spindle and elongated cells (pseudo-lobular) were observed, presence of long cytoplasmic projections with rounded ovoid nucleus, spindle cells and degeneration of seminiferous tubules, compatible with sertolioma. It was observed that physical examination associated with ultrasound was efficient to detect the presence of neoplasms, being validated by histopathological examination. Orchiectomy was an assertive treatment indicated for this case.

Syringoid Eccrine Carcinoma of the Foot: Report of a Rare Cutaneous Adnexal Neoplasm

2017 ◽  
Vol 25 (7) ◽  
pp. 659-664 ◽  
Author(s):  
Woo Cheal Cho ◽  
Brian Wagner ◽  
Melissa Gulosh ◽  
Zendee Elaba
Keyword(s):  
African American Woman ◽  
S100 Protein ◽  
American Woman ◽  
Neck Region ◽  
Immunohistochemical Analysis ◽  
Reticular Dermis ◽  
Plantar Surface ◽  
Adnexal Tumor ◽  
Eccrine Carcinoma ◽  
The Right

Syringoid eccrine carcinoma is a rare malignant adnexal tumor that typically presents in the head and neck region. Involvement of the extremities is uncommon, with only a few cases reported in the literature. Here, we report our experience with a rare case of syringoid eccrine carcinoma occurring on the plantar surface of the right foot in a 47-year-old African American woman. Histologically, incisional biopsy revealed a tumor consisting of tubulocystic structures lined by basaloid cells with an infiltrative growth pattern, extending from the reticular dermis to the deep biopsy margin. Some of the nests and cords of basaloid cells displayed syringoma-like, tadpole morphology. Immunohistochemical analysis showed diffuse immunoreactivity with monoclonal carcinoembryonic antigen, epithelial membrane antigen, cytokeratin 7, S100 protein, and CD117. These morphologic and immunophenotypic features were most consistent with syringoid eccrine carcinoma. Syringoid eccrine carcinoma has a broad differential diagnosis which must be carefully ruled out by morphology, immunohistochemistry, and thorough metastatic survey with imaging studies. Our case highlights the importance of recognizing this rare entity, which is locally destructive and has a propensity for recurrence. To the best of our knowledge, this is the first reported case of syringoid eccrine carcinoma presenting on the sole of the foot.

Preoperative Pulse Pressure and Major Perioperative Adverse Cardiovascular Outcomes After Lower Extremity Vascular Bypass Surgery

2012 ◽  
Vol 114 (6) ◽  
pp. 1177-1181 ◽  
Author(s):  
Amit Asopa ◽  
Srinivas Jidge ◽  
Marc L. Schermerhorn ◽  
Philip E. Hess ◽  
Robina Matyal ◽  
...  
Keyword(s):  
Lower Extremity ◽  
Pulse Pressure ◽  
Bypass Surgery ◽  
Cardiovascular Outcomes ◽  
Vascular Bypass

scholarly journals Cytologic diagnosis of unusual, large multiple cutaneous myxomas in a case of Carney complex

2018 ◽  
Vol 10 (03) ◽  
pp. 354-356
Author(s):  
Manjusha Karegar ◽  
Mrinal Sarwate ◽  
Kanchan Kothari ◽  
Amey Rojekar ◽  
Leena Naik
Keyword(s):  
Needle Aspiration ◽  
Carney Complex ◽  
Cytologic Diagnosis ◽  
Aspiration Cytology ◽  
Significant Family History ◽  
Vascular Proliferation ◽  
Needle Aspiration Cytology ◽  
Cardiac Myxomas ◽  
The Right ◽  
Epithelial Element

ABSTRACTCutaneous myxomas are rare benign neoplasms which are frequently associated with Carney complex (CNC). Although more than 500 cases of CNC are reported, there is no literature on cytologic diagnosis of Cutaneous myxomas. An 18-year-old male, with no significant family history, presented with multiple cutaneous swellings, largest measuring 15 cm on the right cheek. He also had spotty skin pigmentations, raised adrenocorticotropic hormone levels and recurrent cardiac myxomas. Fine-needle aspiration cytology from the right cheek and suprapubic swellings revealed paucicellular smears with abundant myxoid material in the background, admixed with fragments of spindle and stellate cells with bland nuclear morphology, and vascular proliferation in few fragments. There was no mitosis, necrosis, or any epithelial element. Hence, diagnosis of cutaneous myxomas in CNC was made which was confirmed on histopathology. This is the first report of cytologic diagnosis of multiple cutaneous myxomas in CNC and the largest cutaneous myxoma reported in literature.

Sign in / Sign up

Export Citation Format

Share Document