Pulmonary Dysfunction and Massive Transfusion1

2015 ◽  
pp. 220-227
Author(s):  
John A. Collins
Keyword(s):  
Pulmonary Dysfunction

Platelet Function in Surgical Stress

1985 ◽  
Vol 54 (04) ◽  
pp. 849-852 ◽  
Author(s):  
O Naesh ◽  
J T Friis ◽  
I Hindberg ◽  
K Winther
Keyword(s):  
Stress Response ◽  
Negative Correlation ◽  
Surgical Stress ◽  
Plasma Concentrations ◽  
Serum Cortisol ◽  
Cortisol Concentration ◽  
Pulmonary Dysfunction ◽  
Arterial Po2 ◽  
Elective Cholecystectomy ◽  
Serum Cortisol Concentration

SummaryTen patients for elective cholecystectomy were studied pre-, per- and postoperatively. All had neurolept anesthesia. Plasma concentrations of β-TG, TXB2 and 5-HT and intraplatelet 5-HT were measured. Aggregation to ADP was recorded.Serum cortisol concentration was used as index of the stress response, showing peroperative increase and postoperative decrease. Closely related to this we observed a significant increase in P-β-TG and P-TXB2 with postoperative normalization in 6 patients without complications. P-5-HT had a peak peropera-tively and remained elevated postoperatively. A negative correlation between P--5-HT and decreasing intraplatelet 5-HT postoperatively was observed.High postoperative levels of P--5-HT seem to be related to low arterial Po2 and pulmonary dysfunction. In 3 patients with complications a second increase in P-β-TG, P-TXB2 and partly in P--5-HT was found. Platelets were temporarily refractory to ADP immediately following surgery and showed increased aggregabil-ity postoperatively. We conclude that platelets are activated in surgical stress.

Pulmonary dysfunction in surgical conditions of the newborn infant

1991 ◽  
Vol 19 (7) ◽  
pp. 926-933 ◽  
Author(s):  
DON K. NAKAYAMA ◽  
REBECCA MUTICH ◽  
ETSURO K. MOTOYAMA
Keyword(s):  
Newborn Infant ◽  
Pulmonary Dysfunction ◽  
Surgical Conditions

scholarly journals Pulmonary Dysfunction after Treatment for Childhood Cancer: Comparing Multiple-Breath Washout with Spirometry

2020 ◽  
Author(s):  
Christina Schindera ◽  
Jakob Usemann ◽  
Simeon Joel Zuercher ◽  
Ruedi Jung ◽  
Rahel Kasteler ◽  
...  
Keyword(s):  
Childhood Cancer ◽  
Pulmonary Dysfunction ◽  
Multiple Breath Washout

Acadesine and lipopolysaccharide-evoked pulmonary dysfunction after resuscitation from traumatic shock

Surgery ◽  
1996 ◽  
Vol 119 (3) ◽  
pp. 302-315 ◽  
Author(s):  
Timothy C. Fabian ◽  
Matthew J. Fabian ◽  
Jennifer M. Yockey ◽  
Kenneth G. Proctor
Keyword(s):  
Traumatic Shock ◽  
Pulmonary Dysfunction

scholarly journals Albumin Mixed with Meconium Attenuates Pulmonary Dysfunction in a Newborn Piglet Model with Meconium Aspiration

2002 ◽  
Vol 52 (4) ◽  
pp. 545-553 ◽  
Author(s):  
Per Arne Tølløfsrud ◽  
Sverre Medbø ◽  
Anne Beate SolÅs ◽  
Christian A Drevon ◽  
Ola Didrik Saugstad
Keyword(s):  
Newborn Piglet ◽  
Pulmonary Dysfunction ◽  
Meconium Aspiration

scholarly journals Pulmonary dysfunction in cystic fibrosis is associated with oxidative stress

1996 ◽  
Vol 9 (2) ◽  
pp. 334-339 ◽  
Author(s):  
R.K. Brown ◽  
H. Wyatt ◽  
J.F. Price ◽  
F.J. Kelly
Keyword(s):  
Oxidative Stress ◽  
Cystic Fibrosis ◽  
Pulmonary Dysfunction

Restrictive Pulmonary Dysfunction May Increase Blood Loss During Liver Resection

2021 ◽  
pp. 000313482110604
Author(s):  
Takahiro Yoshikawa ◽  
Daisuke Hokuto ◽  
Satoshi Yasuda ◽  
Naoki Kamitani ◽  
Yasuko Matsuo ◽  
...  
Keyword(s):  
Risk Factor ◽  
Liver Resection ◽  
Blood Loss ◽  
Perioperative Outcomes ◽  
Complication Rates ◽  
Pulmonary Dysfunction ◽  
Intraoperative Blood Loss ◽  
Control Groups ◽  
Anatomical Liver Resection ◽  
And Control

Background Restrictive pulmonary dysfunction (RPD) is a risk factor for perioperative complications during gastrointestinal surgery. We hypothesized that high airway pressure due to RPD results in increased intraoperative blood loss during liver surgery. Thus, we investigated the effects of RPD on perioperative outcomes for liver resection. Methods This study included 496 patients who underwent curative liver resection at our hospital between April 2009 and April 2020. Perioperative outcomes for the RPD and control groups were compared. Restrictive pulmonary dysfunction was defined as % vital capacity <80%. Results Forty-one patients (8.3%) had RPD. No significant differences were observed in intraoperative blood losses (440 mL vs 320 mL, P = .340), overall complication rates (29.3% vs 31.2%, P = .797), or pulmonary complication rates (4.9% vs 9.0%, P = .286) between the RPD and control groups. In the 256 patients who underwent anatomical liver resection, 18 patients (7.0%) had RPD. The intraoperative blood loss was significantly higher in the RPD group (925 mL vs 456 mL, P = .013), but no differences in the overall complication rates (44.4% vs 37.3%, P = .528) or pulmonary complication rates (11.1% vs 10.5%, P = .589) between the two groups were detected. A multivariate analysis showed that RPD was an independent risk factor for intraoperative blood loss ≥500 mL during anatomical liver resection (odds ratio 4.132; 95% confidence interval 1.135-15.045; P = .031). Discussion Restrictive pulmonary dysfunction may be a risk factor for intraoperative blood loss during anatomical liver resection, which requires exposure of the main hepatic vein.

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