Goldblatt Hypertension in Rats: A Model for Unilateral Renal Artery Stenosis in Man

2015 ◽  
pp. 134-138 ◽  
Author(s):  
Gerd Schwietzer ◽  
Karl-Heinz Gertz
Keyword(s):  
Renal Artery ◽  
Renal Artery Stenosis ◽  
Artery Stenosis ◽  
Goldblatt Hypertension

Unraveling the Mystery of Goldblatt Hypertension

Physiology ◽  
1998 ◽  
Vol 13 (4) ◽  
pp. 170-176 ◽  
Author(s):  
L. Gabriel Navar ◽  
Lixian Zou ◽  
Annette Von Thun ◽  
Chi Tarng Wang ◽  
John D. Imig ◽  
...  
Keyword(s):  
Angiotensin Ii ◽  
Renal Artery ◽  
Renal Artery Stenosis ◽  
Artery Stenosis ◽  
Ang Ii ◽  
Goldblatt Hypertension

In hypertension caused by unilateral renal artery stenosis, the nonstenotic kidney becomes renin depleted but fails to prevent hypertension. The nonstenotic kidney mysteriously develops elevated intrarenal angiotensin II (ANG II) content. Rats chronically infused with ANG II exhibit a similar hypertensive process. The augmentation of intrarenal ANG II is due to receptor-mediated internalization and continued ANG II formation, which provide a hypertensinogenic stimulus.

Regression of Left Ventricular Hypertrophy Following Stenting of Renal Artery Stenosis

2007 ◽  
Vol 14 (2) ◽  
pp. 189-197 ◽  
Author(s):  
Thomas Zeller ◽  
Aljoscha Rastan ◽  
Uwe Schwarzwälder ◽  
Christian Müller ◽  
Ulrich Frank ◽  
...  
Keyword(s):  
Left Ventricular Hypertrophy ◽  
Renal Artery ◽  
Renal Artery Stenosis ◽  
Ventricular Hypertrophy ◽  
Left Ventricular ◽  
Artery Stenosis
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