Diagnosis of Malignant Ocular Tumours with Radioactive Phosphorus (32P)

2015 ◽  
pp. 168-170
Author(s):  
R. A. van Dijk ◽  
J. A. Oosterhuis
1976 ◽  
Vol 173 (3-4) ◽  
pp. 168-170
Author(s):  
R.A. van Dijk ◽  
J.A. Oosterhuis

1949 ◽  
Vol 3 (4) ◽  
pp. 331-341 ◽  
Author(s):  
ULF BORELL ◽  
HJALMAR HOLMGREN

1938 ◽  
Vol 126 (2) ◽  
pp. 493-500 ◽  
Author(s):  
G.W. Changus ◽  
I.L. Chaikoff ◽  
S. Ruben

Endoscopy ◽  
2021 ◽  
Author(s):  
Jeevinesh Naidu ◽  
Dylan Bartholomeusz ◽  
Joshua Zobel ◽  
Romina Safaeian ◽  
William Hsieh ◽  
...  

Aim: This study evaluated clinical outcomes of combined chemotherapy and Endoscopic Ultrasound (EUS) guided intra-tumoral radioactive phosphorus-32 (32P OncoSil) implantation in locally advanced pancreatic adenocarcinoma (LAPC). Methods: Consecutive patients with a new histological diagnosis of LAPC were recruited over 20 months. Baseline CT and 18FDG PET-CT were performed and repeated after 12 weeks to assess response to treatment. Following 2 cycles of conventional chemotherapy, patients underwent EUS-guided 32P OncoSil implantation followed by a further six cycles of chemotherapy. Results: Twelve patients with LAPC (8M:4F; median age 69 years, IQR 61.5-73.3) completed the treatment. Technical success was 100% and no procedural complications were reported. At 12 weeks, there was a median reduction of 8.2cm3 (95% CI 4.95-10.85; p=0.003) in tumour volume, with minimal or no 18FDG uptake in 9 (75%) patients. Tumour downstaging was achieved in 6 (50%) patients, leading to successful resection in 5 (42%) patients, of which 4 patients (80%) had clear (R0) resection margins. Conclusions: EUS guided 32P OncoSil implantation is feasible and well tolerated and was associated with a 42% rate of surgical resection in our cohort. However, further evaluation in a larger randomized multicenter trial is warranted. (32P funded by OncoSil Medical Ltd, equipment and staff funded by the Royal Adelaide Hospital, ClinicalTrials.gov number, NCT03003078).


1949 ◽  
Vol 7 (2) ◽  
pp. 259
Author(s):  
R.T. Nieset ◽  
Blanche Porter ◽  
W.S. Trautman ◽  
Ralph M. Bell ◽  
William Parson ◽  
...  

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