Vaccination of Cynomolgus Monkeys with Whole Inactivated or Live-Attenuated Simian Immunodeficiency Virus

2015 ◽  
pp. 131-138
Author(s):  
Fausto Titti ◽  
Leonardo Sernicola ◽  
Franco Corrias ◽  
Alessandra Borsetti ◽  
Maria Teresa Maggiorella ◽  
...  
Keyword(s):  
Simian Immunodeficiency Virus ◽  
Cynomolgus Monkeys ◽  
Immunodeficiency Virus

Prevention of simian immunodeficiency virus, SIVsm, or HIV-2 infection in cynomolgus monkeys by pre- and postexposure administration of BEA-005

AIDS ◽  
1997 ◽  
Vol 11 (2) ◽  
pp. 157-162 ◽  
Author(s):  
Disa Böttiger ◽  
Nils-Gunnar Johansson ◽  
Bengt Samuelsson ◽  
Hong Zhang ◽  
Per Putkonen ◽  
...  
Keyword(s):  
Simian Immunodeficiency Virus ◽  
Cynomolgus Monkeys ◽  
Immunodeficiency Virus

scholarly journals Treatment of Acute SIV infection in cynomolgus Monkeys with 2′,3′-dideoxyinosine (ddl) and 2′,3′-dideoxythymidiene (d4T)

1991 ◽  
Vol 2 (6) ◽  
pp. 357-361 ◽  
Author(s):  
D. Böttiger ◽  
E. Ljungdahl-Ståhle ◽  
B. Öberg
Keyword(s):  
Human Immunodeficiency Virus ◽  
Simian Immunodeficiency Virus ◽  
Significant Delay ◽  
Virus Inoculation ◽  
Cynomolgus Monkeys ◽  
Immunodeficiency Virus ◽  
Daily Dose ◽  
Siv Infection ◽  
Antigen A

2′,3′-dideoxyinosine (ddl) and 2′,3′-dideoxythymidiene (d4T) have been reported to inhibit the multiplication of human immunodeficiency virus (HIV) in patients, ddl and d4T were administered subcutaneously to cynomolgus monkeys starting 8 h prior to inoculation with 10–50 infectious doses of simian immunodeficiency virus (SIVSM). ddl, at a daily dose of 3 × 3.6 mg kg−1 for 10 days significantly delayed the appearance of SIVSM p24/26 antigen. A significant delay in the appearance of SIVSM p24/26 antigen was also seen when using a daily dose of 3 × 1 mg kg −1 of d4T for 10 days. Neither ddl nor d4T prevented SIVSM infection despite administration prior to virus inoculation.

Clinical features and predictive markers of disease progression in cynomolgus monkeys experimentally infected with simian immunodeficiency virus

AIDS ◽  
1992 ◽  
Vol 6 (3) ◽  
pp. 257-264 ◽  
Author(s):  
Per Putkonen ◽  
Ephata E. Kaaya ◽  
Disa Böttiger ◽  
Su-Ling Li ◽  
Charlotta Nilsson ◽  
...  
Keyword(s):  
Disease Progression ◽  
Simian Immunodeficiency Virus ◽  
Clinical Features ◽  
Predictive Markers ◽  
Cynomolgus Monkeys ◽  
Immunodeficiency Virus

scholarly journals Coreceptor Usage of Sequential Isolates from Cynomolgus Monkeys Experimentally Infected with Simian Immunodeficiency Virus (SIVsm)

Virology ◽  
2001 ◽  
Vol 291 (1) ◽  
pp. 12-21 ◽  
Author(s):  
Dalma Vödrös ◽  
Rigmor Thorstensson ◽  
Gunnel Biberfeld ◽  
Dominique Schols ◽  
Erik De Clercq ◽  
...  
Keyword(s):  
Simian Immunodeficiency Virus ◽  
Coreceptor Usage ◽  
Cynomolgus Monkeys ◽  
Immunodeficiency Virus

Detection of simian immunodeficiency virus (SIV)-specific T-cell-mediated cytotoxicity in the peripheral blood from infected cynomolgus monkeys

1999 ◽  
Vol 28 (6) ◽  
pp. 307-317
Author(s):  
Elie Mavoungou ◽  
Fousseyni S. Touré ◽  
Philippe Yaba ◽  
Aïcha Sall ◽  
André Délicat ◽  
...  
Keyword(s):  
T Cell ◽  
Simian Immunodeficiency Virus ◽  
Peripheral Blood ◽  
Cynomolgus Monkeys ◽  
Immunodeficiency Virus

scholarly journals Long-Lasting Protection by Live Attenuated Simian Immunodeficiency Virus in Cynomolgus Monkeys: No Detection of Reactivation after Stimulation with a Recall Antigen

Virology ◽  
1999 ◽  
Vol 256 (2) ◽  
pp. 291-302 ◽  
Author(s):  
Leonardo Sernicola ◽  
Franco Corrias ◽  
Martin Luther Koanga-Mogtomo ◽  
Silvia Baroncelli ◽  
Simonetta Di Fabio ◽  
...  
Keyword(s):  
Simian Immunodeficiency Virus ◽  
Cynomolgus Monkeys ◽  
Immunodeficiency Virus ◽  
Recall Antigen

scholarly journals Live attenuated simian immunodeficiency virus prevents super-infection by cloned SIVmac251 in cynomolgus monkeys.

1997 ◽  
Vol 78 (10) ◽  
pp. 2529-2539 ◽  
Author(s):  
F Titti ◽  
S Di Fabio ◽  
A Amadori ◽  
F Monardo ◽  
P Verani ◽  
...  
Keyword(s):  
Simian Immunodeficiency Virus ◽  
Cynomolgus Monkeys ◽  
Immunodeficiency Virus ◽  
Super Infection
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