Gamma Knife Radiosurgery for Uveal Melanoma

2015 ◽  
pp. 165-171 ◽  
Author(s):  
Martin Zehetmayer ◽  
Rupert Menapace ◽  
Klaus Kitz ◽  
Adolf Ertl
Keyword(s):  
Gamma Knife ◽  
Uveal Melanoma ◽  
Gamma Knife Radiosurgery

Preliminary results of contrast-enhanced sonography in the evaluation of the response of uveal melanoma to gamma-knife radiosurgery

2015 ◽  
Vol 43 (7) ◽  
pp. 421-430 ◽  
Author(s):  
Massimo Venturini ◽  
Caterina Colantoni ◽  
Giulio Modorati ◽  
Maura Di Nicola ◽  
Annalisa Colucci ◽  
...  
Keyword(s):  
Gamma Knife ◽  
Uveal Melanoma ◽  
Gamma Knife Radiosurgery ◽  
Preliminary Results ◽  
Contrast Enhanced

Predictive factors of radio‐induced complications in 194 eyes undergoing gamma knife radiosurgery for uveal melanoma

2021 ◽  
Author(s):  
Maria Vittoria Cicinelli ◽  
Maura Di Nicola ◽  
Carmen Rosaria Gigliotti ◽  
Marco Battista ◽  
Elisabetta Miserocchi ◽  
...  
Keyword(s):  
Gamma Knife ◽  
Uveal Melanoma ◽  
Predictive Factors ◽  
Gamma Knife Radiosurgery

Gamma knife radiosurgery for uveal melanoma: 12 years of experience

2008 ◽  
Vol 93 (1) ◽  
pp. 40-44 ◽  
Author(s):  
G Modorati ◽  
E Miserocchi ◽  
L Galli ◽  
P Picozzi ◽  
P Rama
Keyword(s):  
Gamma Knife ◽  
Uveal Melanoma ◽  
Gamma Knife Radiosurgery ◽  
Years Of Experience

scholarly journals Gamma knife radiosurgery for the treatment of uveal melanoma and uveal metastases

2017 ◽  
Vol 3 (1) ◽  
Author(s):  
Margaret M. Reynolds ◽  
Andrea L. Arnett ◽  
Ian F. Parney ◽  
Ravi Kumar ◽  
Nadia N. Laack ◽  
...  
Keyword(s):  
Gamma Knife ◽  
Uveal Melanoma ◽  
Gamma Knife Radiosurgery

scholarly journals Gamma Knife Radiosurgery for Uveal Melanoma: A Retrospective Review of Clinical Complications in a Tertiary Referral Center

2019 ◽  
Vol 6 (2) ◽  
pp. 115-122 ◽  
Author(s):  
Giulio Maria Modorati ◽  
Roi Dagan ◽  
Lauge Hjorth Mikkelsen ◽  
Simon Andreasen ◽  
Alfio Ferlito ◽  
...  
Keyword(s):  
Side Effects ◽  
Gamma Knife ◽  
Uveal Melanoma ◽  
Optic Neuropathy ◽  
Gamma Knife Radiosurgery ◽  
Vitreous Hemorrhage ◽  
Neovascular Glaucoma ◽  
Ophthalmological Examination ◽  
Department Of Ophthalmology ◽  
Radiation Induced

Introduction: Gamma knife radiosurgery (GKR) has shown promising results in the treatment of intraocular uveal melanoma (UM) in terms of local tumor control. However, GKR is not free from potentially sight-threatening side effects, including cataract, dry eye disease, vitreous hemorrhage, radiation retinopathy (RR), radiation maculopathy (RM), optic neuropathy, and neovascular glaucoma. The aim of this paper is to report our 20-year experience in UM management with GKR focusing on the rate of clinical treatment-induced complications. Methods: Single-center, retrospective, observational study, including all patients with UM treated at the Ocular Oncology and Uveitis Service, in the Department of Ophthalmology of the San Raffaele Scientific Institute, Milan from September 1993 to September 2018. Clinical charts comprised complete ophthalmological examination with measurement of best-corrected visual acuity, slit-lamp biomicroscopy, intraocular pressure measurement, gonioscopy, and indirect ophthalmoscopy at each visit. B-scan ultrasound (Aviso S, 10 MHz probe; Paris, France), optical coherence tomography (Heidelberg Spectralis; Heidelberg Engineering, Heidelberg, Germany), retinography, and fundus fluorescein angiography (standard or ultra-widefield [UWF; California, Optos, Dunfermline, Scotland, UK]) were performed aiding in the diagnosis of complications. Results: Overall, 194 patients (100 males, 51.6%) were reviewed. The median age at the time of the treatment was 65 years (range 27–89) and all participants were Caucasian. In 185 eyes (95.4%), the tumor was primarily located at the choroid. The median follow-up was 57.6 months; radiation-induced complications were found in 145 eyes (74.7%). Radiation-induced cataract and RR were the most frequent events, with a relative incidence of 41.2 and 34.5%, respectively, followed by neovascular glaucoma (27.3%), optic neuropathy (18.6%), RM (11.4%), vitreous hemorrhage (14.4%), phthisis bulbi (7.7%), hyphema (0.5%), and corneal melting (0.5%). The shorter onset of side effects involved the optic nerve (median 14.9 months) and the macula (median 13.7 months). Conclusion: Despite modern and advanced strategies introduced to limit GKR side effects, cataract and RR still represent a serious limitation of this treatment. Incidence of RR was higher in our cohort compared to other reports, probably due to increased diagnosis rate permitted by UWF retinal imaging.

Clinicopathologic Report of Uveal Melanoma with Persistent Exudative Retinal Detachment after Gamma Knife Radiosurgery

2010 ◽  
Vol 224 (1) ◽  
pp. 16-21 ◽  
Author(s):  
Won Kyung Song ◽  
Woo Ick Yang ◽  
Suk Ho Byeon ◽  
Hyoung Jun Koh ◽  
Oh Woong Kwon ◽  
...  
Keyword(s):  
Retinal Detachment ◽  
Gamma Knife ◽  
Uveal Melanoma ◽  
Gamma Knife Radiosurgery ◽  
Exudative Retinal Detachment
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