Differentiation of Human Basophils and Mast Cells

2015 ◽  
pp. 49-71
Author(s):  
Judah A. Denburg
Keyword(s):  
Mast Cells ◽  
Human Basophils

scholarly journals Ultrastructural Studies of Human Basophils and Mast Cells

2005 ◽  
Vol 53 (9) ◽  
pp. 1043-1070 ◽  
Author(s):  
Ann M. Dvorak
Keyword(s):  
Growth Factor ◽  
Mast Cells ◽  
Cord Blood ◽  
Blood Cells ◽  
De Novo ◽  
Ultrastructural Studies ◽  
Specific Growth Factor ◽  
Cord Blood Cells ◽  
Human Basophils

Ultrastructural studies of human mast cells (HMCs) and basophils (HBs) are reviewed. Sources of HMCs include biopsies of tissue sites and in situ study of excised diseased organs; isolated, partially purified samples from excised organs; and growth-factor-stimulated mast cells that develop de novo in cultures of cord blood cells. Sources of HBs for study include partially purified peripheral blood basophils, basophils in tissue biopsies, and specific growth factor-stimulated basophils arising de novo from cord blood cells. The ultrastructural studies reviewed deal with identity, secretion, vesicles, recovery, and synthesis issues related to the biology of these similar cells.

Further Characterization of Surface Membrane Structures Expressed on Human Basophils and Mast Cells

1990 ◽  
Vol 91 (2) ◽  
pp. 198-203 ◽  
Author(s):  
Peter Valent ◽  
Otto Majdic ◽  
Dieter Maurer ◽  
Michael Bodger ◽  
Manfred Muhm ◽  
...  
Keyword(s):  
Mast Cells ◽  
Surface Membrane ◽  
Membrane Structures ◽  
Human Basophils

Perspectives on the Regulation of Secretion from Human Basophils and Mast Cells

2000 ◽  
pp. 195-207 ◽  
Author(s):  
Macglashan JR Donald ◽  
Sandra Lavens-Phillips ◽  
Katsushi Miura
Keyword(s):  
Mast Cells ◽  
Regulation Of Secretion ◽  
Human Basophils

Lipoxygenase Products of Arachidonic Acid: their Role in Inflammatory Events Mediated by Human Basophils and Mast Cells

1983 ◽  
pp. 617-622 ◽  
Author(s):  
S.P. PETERS ◽  
R.P. SCHLEIMER ◽  
D.W. MacGLASHAN ◽  
E.S. SCHULMAN ◽  
A. KAGEY-SOBOTKA ◽  
...  
Keyword(s):  
Arachidonic Acid ◽  
Mast Cells ◽  
Lipoxygenase Products ◽  
Human Basophils

scholarly journals Ultrastructural evidence for the common origin of human mast cells and basophils

Blood ◽  
1980 ◽  
Vol 56 (3) ◽  
pp. 534-540 ◽  
Author(s):  
D Zucker-Franklin
Keyword(s):  
Mast Cells ◽  
Intermediate Cell ◽  
Cell Systems ◽  
Human Mast Cells ◽  
Ultrastructural Evidence ◽  
Myeloproliferative Diseases ◽  
The Common ◽  
Human Basophils ◽  
Comparative Description ◽  
Recent Demonstration

Abstract Although the functional similarity of basophils and mast cells is widely accepted, their distinctive morphological features have been taken to indicate the existence of two different, albeit functionally complementary, cell systems. The recent demonstration that mast cells as well as basophils originate from the bone marrow raises the possibility that these cells derive from the same precursor. This report provides evidence for this theory by describing a distinctive “intermediate” cell possessing the ultrastructural features typical of both basophils and mast cells. These cells were encountered in three patients with myeloproliferative diseases and may thus be more readily found in states of disturbed myelopoiesis. These observations have given impetus for the first comparative description of the ultrastructure of human basophils, human mast cells, and the newly recognized intermediate cell within a single report.

scholarly journals Human C5a Induces a Substantial Histamine Release in Human Basophils but Not in Tissue Mast Cells

1988 ◽  
Vol 85 (4) ◽  
pp. 487-488 ◽  
Author(s):  
H. Jürgensen ◽  
U. Braam ◽  
P. Pult ◽  
E. Kownatzki ◽  
W. Schmutzler
Keyword(s):  
Mast Cells ◽  
Histamine Release ◽  
Human Basophils
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