High Resolution Linkage Map of Mouse Chromosome 11 Consisting of Microsatellite Markers Based on Single Intersubspecific Backcross

2015 ◽  
pp. 299-302
Author(s):  
Shigeharu Wakana ◽  
Toshihiko Shiroishi ◽  
Nobumoto Miyashita ◽  
Kazuo Moriwaki ◽  
Hideki Kaneda ◽  
...  
Keyword(s):  
High Resolution ◽  
Microsatellite Markers ◽  
Linkage Map ◽  
Mouse Chromosome ◽  
Chromosome 11 ◽  
Mouse Chromosome 11

A high-resolution map around the locus Om on mouse Chromosome 11

1996 ◽  
Vol 7 (2) ◽  
pp. 114-116 ◽  
Author(s):  
P. A. Baldacci ◽  
M. Cohen-Tannoudji ◽  
C. Kress ◽  
S. Pournin ◽  
C. Babinet
Keyword(s):  
High Resolution ◽  
Mouse Chromosome ◽  
Chromosome 11 ◽  
High Resolution Map ◽  
Mouse Chromosome 11 ◽  
Resolution Map

scholarly journals Patterns of Recombination Activity on Mouse Chromosome 11 Revealed by High Resolution Mapping

PLoS ONE ◽  
2010 ◽  
Vol 5 (12) ◽  
pp. e15340 ◽  
Author(s):  
Timothy Billings ◽  
Evelyn E. Sargent ◽  
Jin P. Szatkiewicz ◽  
Nicole Leahy ◽  
Il-Youp Kwak ◽  
...  
Keyword(s):  
High Resolution ◽  
Mouse Chromosome ◽  
Chromosome 11 ◽  
Recombination Activity ◽  
High Resolution Mapping ◽  
Resolution Mapping ◽  
Mouse Chromosome 11

scholarly journals A comprehensive genetic map of murine chromosome 11 reveals extensive linkage conservation between mouse and human.

Genetics ◽  
1989 ◽  
Vol 122 (1) ◽  
pp. 153-161 ◽  
Author(s):  
A M Buchberg ◽  
E Brownell ◽  
S Nagata ◽  
N A Jenkins ◽  
N G Copeland
Keyword(s):  
Human Chromosome ◽  
Linkage Map ◽  
Mouse Chromosome ◽  
Chromosome 17 ◽  
Human Chromosomes ◽  
Chromosome 11 ◽  
Murine Chromosome ◽  
Human Chromosome 17 ◽  
Mouse Chromosome 11 ◽  
Linkage Conservation

Abstract Interspecific backcross animals from a cross between C57BL/6J and Mus spretus mice were used to generate a comprehensive linkage map of mouse chromosome 11. The relative map positions of genes previously assigned to mouse chromosome 11 by somatic cell hybrid or genetic backcross analysis were determined (Erbb, Rel, 11-3, Csfgm, Trp53-1, Evi-2, Erba, Erbb-2, Csfg, Myhs, Cola-1, Myla, Hox-2 and Pkca). We also analyzed genes that we suspected would map to chromosome 11 by virtue of their location in human chromosomes and the known linkage homologies that exist between murine chromosome 11 and human chromosomes (Mpo, Ngfr, Pdgfr and Fms). Two of the latter genes, Mpo and Ngfr, mapped to mouse chromosome 11. Both genes also mapped to human chromosome 17, extending the degree of linkage conservation observed between human chromosome 17 and mouse chromosome 11. Pdgfr and Fms, which are closely linked to II-3 and Csfgm in humans on chromosome 5, mapped to mouse chromosome 18 rather than mouse chromosome 11, thereby defining yet another conserved linkage group between human and mouse chromosomes. The mouse chromosome 11 linkage map generated in these studies substantially extends the framework for identifying homologous genes in the mouse that are involved in human disease, for elucidating the genes responsible for several mouse mutations, and for gaining insights into chromosome evolution and genome organization.

scholarly journals Mapping of the nu gene using congenic nude strains and in situ hybridization.

1992 ◽  
Vol 175 (3) ◽  
pp. 873-876 ◽  
Author(s):  
Y Takahashi ◽  
A Shimizu ◽  
T Sakai ◽  
Y Endo ◽  
N Osawa ◽  
...  
Keyword(s):  
In Situ Hybridization ◽  
High Resolution ◽  
Mouse Chromosome ◽  
Nude Mouse ◽  
Physical Mapping ◽  
Dna Markers ◽  
Chromosomal Location ◽  
Chromosome 11 ◽  
Mouse Chromosome 11

The chromosomal location of the nu gene, which is responsible for hairlessness and athymus, was determined using six DNA markers (interleukin 3 [Il-3], Myhs, Acrb, Evi-2, Mpo, and Hox-2) on mouse chromosome 11. We constructed the high-resolution physical mapping of the six DNA markers on chromosome 11 by in situ hybridization using fluorescence-labeled cosmid probes. The results indicate the order of centromere-(41cM)-Il-3-(3cM)-Myhs- (4cM)-Acrb-(6cM)-Evi-2-(3cM)-Mpo-(5cM)- Hox-2. We have used congenic nude strains and examined which of the six DNA markers were derived from the original nude mouse. We found the Evi-2 locus is linked to the nu gene in all the informative, independent congenic nude strains. From these data, we could estimate the location of the nu gene, not only genetically but also physically within a region that spans approximately 17 megabases (9 cM) between the Acrb and Mpo genes.

YAC/P1 contigs defining the location of 56 microsatellite markers and several genes across a 3.4-cM interval on mouse Chromosome 11

1995 ◽  
Vol 6 (5) ◽  
pp. 321-331 ◽  
Author(s):  
M. Nehls ◽  
K. L�no ◽  
M. Schorpp ◽  
D. Pfeifer ◽  
S. Krause ◽  
...  
Keyword(s):  
Microsatellite Markers ◽  
Mouse Chromosome ◽  
Chromosome 11 ◽  
Mouse Chromosome 11
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