Fusion Protein-Mediated Tumor-Selective Prodrug Activation

1995 ◽  
pp. 160-169
Author(s):  
Klaus Bosslet ◽  
Jörg Czech ◽  
Dieter Hoffmann
Keyword(s):  
Fusion Protein ◽  
Prodrug Activation ◽  
Tumor Selective

Improved Yield and Stability of L49-sFv−β-Lactamase, a Single-Chain Antibody Fusion Protein for Anticancer Prodrug Activation, by Protein Engineering

2003 ◽  
Vol 14 (5) ◽  
pp. 860-869 ◽  
Author(s):  
Charlotte F. McDonagh ◽  
Kevin S. Beam ◽  
Gabrielle J. S. Wu ◽  
Judy H. Chen ◽  
Dana F. Chace ◽  
...  
Keyword(s):  
Protein Engineering ◽  
Fusion Protein ◽  
Single Chain ◽  
Single Chain Antibody ◽  
Prodrug Activation ◽  
Antibody Fusion Protein ◽  
Anticancer Prodrug

Fusion protein mediated prodrug activation (FMPA) in vivo

1994 ◽  
Vol 24-25 (1-3) ◽  
pp. 51-63 ◽  
Author(s):  
K. Bosslet ◽  
J. Czech ◽  
G. Seemann ◽  
C. Monneret ◽  
D. Hoffmann
Keyword(s):  
Fusion Protein ◽  
Prodrug Activation

Construction, Expression, and Activities of L49-sFv-β-Lactamase, a Single-Chain Antibody Fusion Protein for Anticancer Prodrug Activation

1997 ◽  
Vol 8 (4) ◽  
pp. 510-519 ◽  
Author(s):  
Nathan O. Siemers ◽  
David E. Kerr ◽  
Susan Yarnold ◽  
Mark R. Stebbins ◽  
Vivekananda M. Vrudhula ◽  
...  
Keyword(s):  
Fusion Protein ◽  
Single Chain ◽  
Single Chain Antibody ◽  
Prodrug Activation ◽  
Antibody Fusion Protein ◽  
Anticancer Prodrug

scholarly journals Molecular and functional characterisation of a fusion protein suited for tumour specific prodrug activation

1992 ◽  
Vol 65 (2) ◽  
pp. 234-238 ◽  
Author(s):  
K Bosslet ◽  
J Czech ◽  
P Lorenz ◽  
HH Sedlacek ◽  
M Schuermann ◽  
...  
Keyword(s):  
Fusion Protein ◽  
Prodrug Activation ◽  
Functional Characterisation

The oncolytic adenovirus Ad-iREP-2 utilizes p53-dependent rna interference for tumor-selective replication

2008 ◽  
Vol 46 (09) ◽  
Author(s):  
E Gürlevik ◽  
P Schache ◽  
L Zender ◽  
MP Manns ◽  
S Kubicka ◽  
...  
Keyword(s):  
Rna Interference ◽  
Oncolytic Adenovirus ◽  
Tumor Selective
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