Alleviation of Autoimmune Disease by ?3 Fatty Acids

2015 ◽  
pp. 95-102 ◽  
Author(s):  
Dwight R. Robinson ◽  
Li-Lian Xu ◽  
Christopher T. Knoell ◽  
Sumio Tateno ◽  
Muyi Guo ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Autoimmune Disease

scholarly journals Dietary behavior and the course of psoriasis

2021 ◽  
Vol 10 (2) ◽  
pp. 69-74
Author(s):  
Klaudia Lorbiecka ◽  
Keyword(s):  
Fatty Acids ◽  
Eating Disorders ◽  
Autoimmune Disease ◽  
Molecular Mechanisms ◽  
Eating Habits ◽  
Scientific Publications ◽  
Balanced Diet ◽  
The Many ◽  
The Right ◽  
The Relationship

Psoriasis is a chronic, inflammatory and autoimmune disease that affects approximately 2% of the world’s population. The pathogenesis of this disease is complex, and despite the many mechanisms responsible for the development of psoriasis have been explained, it is still not fully understood. Scientific publications provide more and more recent information on the molecular mechanisms of psoriasis and the relationship between the course of the disease and eating habits. The aim of the study was to determine the influence of eating habits on the course of psoriasis and to present compounds that have proven effectiveness in alleviating the course of this disease. Numerous reports indicate that certain eating disorders affect the course of the disease It is suggested that a properly balanced diet, providing the right amount of polyunsaturated fatty acids, antioxidants, micro and macro elements, may have anti-inflammatory effects and not only significantly reduce the severity of psoriasis lesions, but also increase the patient’s comfort of life.

scholarly journals Suppression of autoimmune disease by dietary n-3 fatty acids

1993 ◽  
Vol 34 (8) ◽  
pp. 1435-1444
Author(s):  
DR Robinson ◽  
LL Xu ◽  
S Tateno ◽  
M Guo ◽  
RB Colvin
Keyword(s):  
Fatty Acids ◽  
Autoimmune Disease

Inhibition of Osteoporosis in Autoimmune Disease Prone MRL/Mpj-FaslprMice by N-3 Fatty Acids

2005 ◽  
Vol 24 (3) ◽  
pp. 200-209 ◽  
Author(s):  
Arunabh Bhattacharya ◽  
Mizanur Rahman ◽  
Jameela Banu ◽  
Richard A. Lawrence ◽  
Howard S. McGuff ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Autoimmune Disease

Suppression of autoimmune disease by ω – 3 fatty acids

1995 ◽  
Vol 23 (2) ◽  
pp. 287-291 ◽  
Author(s):  
D. R. Robinson ◽  
C. T. Knoell ◽  
M. Urakaze ◽  
R. Huang ◽  
H. Taki ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Autoimmune Disease

scholarly journals Associations between methylmercury, n-3 polyunsaturated fatty acids and antinuclear antibodies in young adults from the Seychelles Child Development Study (SCDS).

2020 ◽  
Vol 79 (OCE2) ◽  
Author(s):  
Emeir M. McSorley ◽  
Maria S. Mulhern ◽  
Alison J. Yeates ◽  
Donald Harrington ◽  
Edwin van Wijngaarden ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Autoimmune Disease ◽  
Polyunsaturated Fatty Acids ◽  
Fish Consumption ◽  
Antinuclear Antibodies ◽  
Weighted Average ◽  
Mehg Exposure ◽  
Total N ◽  
Negatively Associated ◽  
Exposure Metrics

AbstractThe association of MeHg exposure through fish consumption on human autoimmunity remains unclear. Fish also contain n-3 long chain polyunsaturated fatty acids (LCPUFA) that are known to regulate inflammation and mitigate autoimmune disease symptoms. We studied the association of low-level exposure to methylmercury (MeHg) through fish consumption in the SCDS. We examined this association at age 19 years in the SCDS Main Cohort (n = 497). We measured MeHg exposure at 3 time points [prenatal, weighted average (6 months to 19 years) and concurrent (19 years) and LCPUFA status and a panel of 13 autoimmune markers at age 19 years. The autoimmune markers included antinuclear antibodies (ANA), anti-dsDNA and anti-RNP, and total (non-specific) immunoglobulins (Ig) IgG, IgA, and IgM. A combined ANA variable was also calculated based on being within or above reference range for any of the ANA markers; 56% of the subjects met this criterion. Multivariable regression models adjusted for prenatal MeHg, sex and waist circumference, with and without adjustment for LCPUFA, were fit for the three MeHg exposure metrics and each immune marker. Mean (SD) prenatal, weighted average and concurrent MeHg was 6.84 (4.55), 7.46 (2.82), and 10.23 (6.02) ppm, respectively. Combined ANA was positively associated with concurrent MeHg following adjustment for the n6:n3 LCPUFA ratio (β = 0.036, 95%; CI: 0.001, 0.073). Prenatal and average MeHg exposures were not significantly associated with any individual ANA. IgM was negatively associated with concurrent (β = -0.016, 95%CI: -0.016, -0.002), and average (β = -0.042, 95%CI: -0.042, -0.009) MeHg exposure in the models adjusted for n-3, n-6 LCPUFA and when separately adjusted for the n6:n3 LCPUFA ratio. Total (19-year) n-3 PUFA status was negatively associated with anti-RNP (β = -20.355, 95%CI: -36.89, -4.34) and IgG (β = -1.384, 95%CI: -2.682, -0.087). Total n-3 LCPUFA was associated with lower markers of autoimmunity. MeHg exposure at 19 years was associated with higher ANA and lower IgM but only following adjustment for LCPUFA. The clinical significance of these findings is unclear and further research is warranted to determine if these associations precede autoimmune disease development.

Fatty Acids and Glycerides

1979 ◽  
Vol 7 (4) ◽  
pp. 813-814
Author(s):  
J. L. HARWOOD
Keyword(s):  
Fatty Acids
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