The Role of the Descending Pallido-Reticular Pathway in Movement Disorders

Author(s):  
F. Shima ◽  
S. Sakata ◽  
S. -J. Sun ◽  
M. Kato ◽  
M. Fukui ◽  
...  
Keyword(s):  
Author(s):  
Ravi Gupta

Sleep-related movement disorders include disorders that manifest as simple and mostly stereotyped movements occurring at sleep–wake interface or during sleep. Restless legs syndrome (RLS), the most common sleep-related movement disorder. RLS is a treatable condition that psychiatrists must be familiar with due to its common comorbidity with a broad range of psychiatric disorders. In addition, commonly used psychotropic medications are known to induce or worsen RLS symptoms in predisposed individuals, and these symptoms may be mistaken for akathisia or sleep-initiation insomnia and lead to mismanagement. This chapter discusses, among other RLS-related topics, the diagnosis, epidemiology, predisposing factors, genetic factors, and the role of iron metabolism.


2019 ◽  
Vol 7 (2) ◽  
pp. 177-181 ◽  
Author(s):  
Isaiah Kletenik ◽  
Stefan H. Sillau ◽  
Sanaz Attaripour Isfahani ◽  
Kathrin LaFaver ◽  
Mark Hallett ◽  
...  

2020 ◽  
Vol 35 (11) ◽  
pp. 1903-1904 ◽  
Author(s):  
Eoin Mulroy ◽  
Elisa Menozzi ◽  
Andrew J. Lees ◽  
Timothy Lynch ◽  
Anthony E. Lang ◽  
...  
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Author(s):  
Mark Hallett ◽  
Alfredo Berardelli

This article focuses on the potential therapeutic uses of transcranial magnetic stimulation (TMS) in movement disorders. The brain can be stimulated with low levels of direct electrical current, called direct current polarization (tDCS). High-frequency repetitive TMS might increase brain excitability and be used for therapy in Parkinson's disease. Single sessions with TMS, however, have not proven to be very effective. Treatment with tDCS has been performed in some open studies with some success, but these results need confirmation. Physiological findings in dystonia reveal a decrease in intracortical inhibition. There have been a few studies of patients with Tourette's syndrome with mixed results. To date, clinical results with TMS in movement disorders have been mixed, and more work will be needed to clarify the potential clinical role of TMS.


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