Trans Fatty Acids in Early Human Development

2015 ◽  
pp. 175-178 ◽  
Author(s):  
Adriana C. v. Houwelingen ◽  
Gerard Hornstra
Keyword(s):  
Fatty Acids ◽  
Human Development ◽  
Trans Fatty Acids ◽  
Early Human Development ◽  
Early Human

n-6 and n-3 fatty acids during early human development

1989 ◽  
Vol 225 (S731) ◽  
pp. 159-169 ◽  
Author(s):  
M. A. CRAWFORD ◽  
W. DOYLE ◽  
P. DRURY ◽  
A. LENNON ◽  
K. COSTELOE ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Human Development ◽  
Early Human Development ◽  
Early Human

Essential fatty acids in pregnancy and early human development

1995 ◽  
Vol 61 (1) ◽  
pp. 57-62 ◽  
Author(s):  
Gerard Hornstra ◽  
Monique D.M. Al ◽  
Adriana C.v. Houwelingen ◽  
Magritha M.H.P. Foreman-van Drongelen
Keyword(s):  
Fatty Acids ◽  
Human Development ◽  
Essential Fatty Acids ◽  
Early Human Development ◽  
Early Human ◽  
In Pregnancy

Novel application of three-dimensional HDlive imaging in prenatal diagnosis from the first trimester

2015 ◽  
Vol 43 (2) ◽  
Author(s):  
Ritsuko Kimata Pooh ◽  
Asim Kurjak
Keyword(s):  
Human Development ◽  
New Technology ◽  
Three Dimensional ◽  
First Trimester ◽  
High Definition ◽  
Noninvasive Diagnostics ◽  
Anatomy And Physiology ◽  
Early Human Development ◽  
2D Ultrasound ◽  
Early Human

AbstractRecent development of three-dimensional (3D) high definition (HD) ultrasound has resulted in remarkable progress in visualization of early embryos and fetuses in sonoembryology. The new technology of HDlive assesses both structural and functional developments in the first trimester with greater reliably than two-dimensional (2D) ultrasound. The ability to visualize not only fetal face, hands, fingers, feet, and toes, but also amniotic membranes, is better with volumetric ultrasound than 2D ultrasound. In this article, detailed and comprehensive structures of normal and abnormal fetuses depicted by 3D HDlive are presented, including various faces of Down’s syndrome and holoprosencephaly, as well as low-set ear and finger/toe abnormalities from the first trimester. Three-dimensional HDlive further “humanizes” the fetus, enables detailed observation of the fetal face in the first trimester as shown in this article, and reveals that a small fetus is not more a fetus but a “person” from the first trimester. There has been an immense acceleration in understanding of early human development. The anatomy and physiology of embryonic development is a field where medicine exerts greatest impact on early pregnancy at present, and it opens fascinating aspects of embryonic differentiation. Clinical assessment of those stages of growth relies heavily on 3D/four-dimensional (4D) HDlive, one of the most promising forms of noninvasive diagnostics and embryological phenomena, once matters for textbooks are now routinely recorded with outstanding clarity. New advances deserve the adjective “breathtaking”, including 4D parallel study of the structural and functional early human development.

scholarly journals Opening the black box: Stem cell–based modeling of human post-implantation development

2018 ◽  
Vol 218 (2) ◽  
pp. 410-421 ◽  
Author(s):  
Kenichiro Taniguchi ◽  
Idse Heemskerk ◽  
Deborah L. Gumucio
Keyword(s):  
Stem Cell ◽  
Human Development ◽  
Experimental Models ◽  
Uterine Wall ◽  
Black Box ◽  
Cellular Mechanisms ◽  
Early Human Development ◽  
Post Implantation ◽  
Early Human

Proper development of the human embryo following its implantation into the uterine wall is critical for the successful continuation of pregnancy. However, the complex cellular and molecular changes that occur during this post-implantation period of human development are not amenable to study in vivo. Recently, several new embryo-like human pluripotent stem cell (hPSC)–based platforms have emerged, which are beginning to illuminate the current black box state of early human post-implantation biology. In this review, we will discuss how these experimental models are carving a way for understanding novel molecular and cellular mechanisms during early human development.

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