Trophic Action of Gastrin on Specific Target Cells in the Gut

2015 ◽  
pp. 30-44 ◽  
Author(s):  
Gerard Willems
Keyword(s):  
Target Cells ◽  
Specific Target ◽  
Trophic Action

scholarly journals THYMOCYTES FROM MICE IMMUNIZED AGAINST AN ALLOGRAFT RENDER BONE-MARROW CELLS SPECIFICALLY CYTOTOXIC

1972 ◽  
Vol 135 (1) ◽  
pp. 150-164 ◽  
Author(s):  
C. K. Grant ◽  
G. A. Currie ◽  
P. Alexander
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Cells ◽  
Target Cells ◽  
Cytotoxic Action ◽  
Specific Target ◽  
C57bl Mice ◽  
Specific Increase ◽  
Spleen And Lymph Nodes ◽  
Marrow Cells

Thymocytes from C57BL mice immunized with the DBA/2 lymphoma L5178Y exert in vitro an immunologically specific cytotoxic action against the target cells in the presence of bone-marrow cells. Neither the nonimmune bone marrow nor the immune thymocytes are by themselves cytotoxic. The cells in the bone marrow which take part in the cytotoxic action adhere to glass and are sensitive to anti-macrophage serum. These bone-marrow cells can also be rendered specifically cytotoxic by exposure to the supernatant obtained from a culture of immune thymocytes with the specific target cells. The thymocytes before they are confronted with the specific target cells are very radiosensitive; however, on coming into contact with the target cells, an immunologically specific increase in RNA synthesis occurs and thereafter the thymocytes' capacity to render bone-marrow cells cytotoxic is relatively radioresistant. Two classes of immune lymphocytes occur in mice immunized with allogeneic cells, those that are capable of killing target cells directly and those that produce a factor capable of rendering macrophages (or monocytes) specifically cytotoxic. In the thymus of immune animals only the latter are found while both categories are present in the spleen and lymph nodes of immune animals.

ELISPOT and functional T cell analyses using HLA mono-specific target cells

2009 ◽  
Vol 350 (1-2) ◽  
pp. 150-160 ◽  
Author(s):  
Claire Horlock ◽  
Bryony Stott ◽  
Julian Dyson ◽  
Graham Ogg ◽  
Tess McPherson ◽  
...  
Keyword(s):  
T Cell ◽  
Target Cells ◽  
Specific Target

Self-assembled multifunctional DNA nanospheres for biosensing and drug delivery into specific target cells

Nanoscale ◽  
2015 ◽  
Vol 7 (16) ◽  
pp. 7361-7367 ◽  
Author(s):  
Sai Bi ◽  
Ying Dong ◽  
Xiaoqiang Jia ◽  
Min Chen ◽  
Hua Zhong ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Target Cells ◽  
Specific Target ◽  
Self Assembled

scholarly journals Antigen-Dependent Release of IFN-γ by Cytotoxic T Cells Up-Regulates Fas on Target Cells and Facilitates Exocytosis-Independent Specific Target Cell Lysis

2002 ◽  
Vol 169 (1) ◽  
pp. 145-150 ◽  
Author(s):  
Arno Müllbacher ◽  
Mario Lobigs ◽  
Ron Tha Hla ◽  
Thao Tran ◽  
Thomas Stehle ◽  
...  
Keyword(s):  
T Cells ◽  
Target Cell ◽  
Cytotoxic T Cells ◽  
Cell Lysis ◽  
Target Cells ◽  
Specific Target ◽  
Ifn Γ

TCRAlpha/Beta and TCRGamma/Delta CD4− /CD8− HLA-DR alloreactive CTL clones do not use fas/fas ligand pathway to lyse their specific target cells

1996 ◽  
Vol 51 (1) ◽  
pp. 13-22 ◽  
Author(s):  
Fathia Mami-Chouaib ◽  
Caroline Flament ◽  
Carine Asselin-Paturel ◽  
Catherine Gaudin ◽  
Salem Chouaib
Keyword(s):  
Fas Ligand ◽  
Target Cells ◽  
Specific Target ◽  
Hla Dr

scholarly journals Synthetic Aptamer-Polymer Hybrid Constructs for Programmed Drug Delivery into Specific Target Cells

2014 ◽  
Vol 136 (42) ◽  
pp. 15010-15015 ◽  
Author(s):  
Seung Soo Oh ◽  
Bongjae F. Lee ◽  
Frank A. Leibfarth ◽  
Michael Eisenstein ◽  
Maxwell J. Robb ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Target Cells ◽  
Specific Target ◽  
Polymer Hybrid
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