Importance of Convection in Artificial Kidney Treatment

METABOLIC SYNDROME IN DIALYSIS PATIENTS

Journal of Medicine and Pharmacy ◽

10.34071/jmp.2016.5.1 ◽

2016 ◽

pp. 7-11

Author(s):

Vinh Phu Hoang ◽

Tam Vo ◽

Van Tien Le ◽

Thi Hoai Huong Vo

Keyword(s):

Blood Pressure ◽

Metabolic Syndrome ◽

Renal Failure ◽

Chronic Renal Failure ◽

Artificial Kidney ◽

Dialysis Patients ◽

Cross Sectional ◽

Average Value ◽

The Metabolic Syndrome ◽

End Stage

Objective: To review disorders elements of the metabolic syndrome in patients with end-stage chronic renal failure on dialysis cycle. Materials and methods: A cross sectional descriptive study of 85 patients including end-stage chronic renal failure in dialysis cycle from 5/2015 - 9/2016 at the Department of Artificial Kidney, Hue Central Hospital. Results: The prevalence of metabolic syndrome in dialysis patients was 37.65%. The prevalence of abdominal obesity was 30.6%; The prevalence of hypertension was 72.9%, the average value systolic blood pressure and diastolic blood pressure were 142.24 ± 27.53, 80.35 ± 12.48 mmHg; The prevalence of hyperglycemia was 28%, the average value blood glucose was 4.9 ± 1.19 mmol/l; The prevalence of triglyceride increase was 34.1%, the average value triglyceride was 1.59 ± 0.84 mmol/l. The prevalence of HDL-C increase was 47.1%, the average value HDL-C was 1.24 ± 0.33 mmol/l. Conclusion: The prevalence of metabolic syndrome in dialysis patients is very high, in which hypertension and HDL disturbances are the highest. Key words: chronic renal failure, dialysis, metabolic syndrome

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The effect of ultrafiltration transmembrane permeation on the flow field in a surrogate system of an artificial kidney

Experimental Results ◽

10.1017/exp.2021.5 ◽

2021 ◽

Vol 2 ◽

Author(s):

Matilde De Pascale ◽

Monica Faria ◽

Cristiana Boi ◽

Viriato Semiao ◽

Maria Norberta de Pinho

Keyword(s):

Pressure Drop ◽

Artificial Kidney ◽

Shear Stresses ◽

Removal Rates ◽

Permeable Membrane ◽

Fluid Removal ◽

Renal Replacement Therapies ◽

Extracorporeal Blood Circulation ◽

Conventional Hemodialysis ◽

Upper Chamber

Abstract Renal Replacement Therapies generally associated to the Artificial Kidney (AK) are membrane-based treatments that assure the separation functions of the failing kidney in extracorporeal blood circulation. Their progress from conventional hemodialysis towards high-flux hemodialysis (HFHD) through the introduction of ultrafiltration membranes characterized by high convective permeation fluxes intensified the need of elucidating the effect of the membrane fluid removal rates on the increase of the potentially blood-traumatizing shear stresses developed adjacently to the membrane. The AK surrogate consisting of two-compartments separated by an ultrafiltration membrane is set to have water circulation in the upper chamber mimicking the blood flow rates and the membrane fluid removal rates typical of HFHD. Pressure drop mirrors the shear stresses quantification and the modification of the velocities profiles. The increase on pressure drop when comparing flows in slits with a permeable membrane and an impermeable wall is ca. 512% and 576% for $ \mathrm{CA}22/5\%{\mathrm{SiO}}_2 $ and $ \mathrm{CA}30/5\%{\mathrm{SiO}}_2 $ membranes, respectively.

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