Normal Variability of Human Capillary Blood Pressure

2015 ◽  
pp. 81-86 ◽  
Author(s):  
A. C. Shore ◽  
J. E. Tooke ◽  
D. D. Sandeman
Keyword(s):  
Blood Pressure ◽  
Capillary Blood ◽  
Normal Variability

Lutein Complex Supplementation Increases Ocular Blood Flow Biomarkers in Healthy Subjects

2019 ◽  
Vol 89 (1-2) ◽  
pp. 5-12
Author(s):  
Alon Harris ◽  
Brent Siesky ◽  
Amelia Huang ◽  
Thai Do ◽  
Sunu Mathew ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Blood Flow ◽  
Diastolic Blood Pressure ◽  
Healthy Subjects ◽  
Ocular Blood Flow ◽  
Capillary Blood ◽  
Post Treatment ◽  
Capillary Blood Flow ◽  
Doppler Imaging ◽  
Retinal Capillary

Abstract. Introduction: To investigate the effects of a lutein complex supplementation on ocular blood flow in healthy subjects. Materials and Methods: Sixteen healthy female patients (mean age 36.8 ± 12.1 years) were enrolled in this randomized, placebo-controlled, double-blinded, two-period crossover study. Subjects received daily an oral dose of the lutein with synergistic phytochemicals complex (lutein (10 mg), ascorbic acid (500 mg), tocopherols (364 mg), carnosic acid (2.5 mg), zeaxanthin (2 mg), copper (2 mg), with synergistic effects in reducing pro-inflammatory mediators and cytokines when administered together in combination) and placebo during administration periods. Measurements were taken before and after three-week supplementation periods, with crossover visits separated by a three-week washout period. Data analysis included blood pressure, heart rate, intraocular pressure, visual acuity, contrast sensitivity detection, ocular perfusion pressure, confocal scanning laser Doppler imaging of retinal capillary blood flow, and Doppler imaging of the retrobulbar blood vessels. Results: Lutein complex supplementation produced a statistically significant increase in mean superior retinal capillary blood flow, measured in arbitrary units (60, p = 0.0466) and a decrease in the percentage of avascular area in the superior (−0.029, p = 0.0491) and inferior (−0.023, p = 0.0477) retina, as well as reduced systolic (−4.06, p = 0.0295) and diastolic (−3.69, p = 0.0441) blood pressure measured in mmHg from baseline. Data comparison between the two supplement groups revealed a significant decrease in systemic diastolic blood pressure (change from pre- to post-treatment with lutein supplement (mean (SE)): −3.69 (1.68); change from pre- to post-treatment with placebo: 0.31 (2.57); p = 0.0357) and a significant increase in the peak systolic velocity (measured in cm/sec) in the central retinal artery (change from pre- to post-treatment with lutein supplement: 0.36 (0.19); change from pre- to post-treatment with placebo: −0.33 (0.21); p = 0.0384) with lutein complex supplement; data analyses from the placebo group were all non-significant. Discussion: In healthy participants, oral administration of a lutein phytochemicals complex for three weeks produced increased ocular blood flow biomarkers within retinal vascular beds and reduced diastolic blood pressure compared to placebo.

Evaluation of the hypomagnetic environment effects on capillary blood circulation, blood pressure, and heart rate

2016 ◽  
Vol 42 (7) ◽  
pp. 809-814 ◽  
Author(s):  
Yu. I. Gurfinkel ◽  
A. L. Vasin ◽  
T. A. Matveeva ◽  
M. L. Sasonko
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Blood Circulation ◽  
Capillary Blood ◽  
Environment Effects

scholarly journals Observations on changes in the blood pressure and blood volume following operations in man. (Preliminary communication.)

1919 ◽  
Vol 90 (632) ◽  
pp. 415-437 ◽  
Keyword(s):  
Blood Pressure ◽  
Blood Volume ◽  
Capillary Blood ◽  
Volume Changes ◽  
Auscultatory Method ◽  
Blood Pressures ◽  
Preliminary Communication ◽  
Haemoglobin Content

The cases here investigated were wounded men undergoing operations, and repeated examinations were usually made. Most of the cases showed only slight symptoms of shock. Methods .—The systolic and diastolic blood pressures were measured before, during, and after operations, a Riva Rocci apparatus being used. The auscultatory method recommended by Oliver was used to determine the two levels. The hæmoglobin was estimated also, as far as possible, at the same time. The actual level of the hæmoglobin value was read by Haldane’s method, while the changes in any patient were determined by comparison of the different samples in a Du Borscq colourimeter. For this purpose suspensions of the corpuscles in a dilution of 1 in 200 in saline were used, the volume chosen being 10 c. c., and these samples were hæmolysed with saponin before being read in the colourimeter. For this method I am indebted to Prof. Dreyer, and it has proved more accurate than any other. The blood has been taken always from either the ear or the finger. In estimating the blood volume changes from these readings, it has been assumed that the blood volume varies inversely as the hæmoglobin percentage. During and after operations this will be only relatively true, since hæmorrhage occurs. The amount of blood lost may, however, be roughly estimated by the loss of hæmoglobin in the first 24 hours after operation. In cases of slight shock, equilibrium will probably have been reached in this time. That this is true is indicated by the results obtained and put forward in Case I. In this patient a fair amount of blood was lost during the process of decompression for a fractured skull, and nearly all the blood lost was washed into buckets by a stream of saline running over the wound. The saline in these buckets was collected after the operation and the hæmoglobin content was determined by reading the contents in the Du Borscq colourimeter against a sample of the patient’s own blood, taken before operation. In this way it was calculated that he lost 782 c. c. of blood. By the determination of the change in the hæmoglobin value in 24 hours, it was estimated that he lost 17⋅7 per cent, of his blood volume, and this was reckoned (taking Dreyer’s formula for blood volume) to correspond to a loss of 760 c. c. The agreement was therefore remarkable, and it is probable that the methods are moderately accurate. In all the Tables the calculations of blood volume are made neglecting this factor of hæmorrhage. At the bottom of the Tables the estimated blood lost is given, and in the last column of the Tables corrected values for the blood volume are given in which the hæmorrhage has been approximately allowed for. The results obtained seemed to indicate that the changes in the hæmoglobin percentage of capillary blood do demonstrate the changes seen in the blood volume, provided that the lag due to a slow circulation and partial stasis is allowed for, the hæmoglobin changes following those in the blood pressure.

scholarly journals Prevalence of Risk Factors of non-communicable Diseases in an Adult Population of Rural Bangladesh

2018 ◽  
Vol 10 (2) ◽  
pp. 126-134
Author(s):  
Palash Chandra Banik ◽  
M Mostafa Zaman ◽  
Jasimuddin Ahmed ◽  
Sohel Reza Choudhury ◽  
Mohammad Moniruzzaman
Keyword(s):  
Physical Activity ◽  
Risk Factors ◽  
Blood Pressure ◽  
Adult Population ◽  
Lifestyle Changes ◽  
Capillary Blood ◽  
Blood Cholesterol ◽  
Noncommunicable Diseases ◽  
Sample Treatment ◽  
Treatment Rate

Background:A community based survey was carried out to determine the distribution of major noncommunicable diseases risk factors as well as to explore the detection and treatment rate of diabetes mellitus and hypertension in rural adult population of Bangladesh.Methods: The survey was done in2006 among 545 individualsaged 25 to 64 years randomly drawn from a village (Ekhlaspur under Chandpur district) of Bangladesh. Information on diet, physical activity, alcohol and tobacco, and treatment history for hypertension and diabetes were collected. Height, weight, waist circumference, blood pressure, capillary blood glucose and total cholesterol were measured.Results: There were 269 men and 276 women with the mean age of 43.9 years (standard deviation, 11.6 years). Six in ten (62.4%) of them used tobacco in some form (smoking or smokeless), 93.7% did not consume adequate fruits and vegetables (five servings or more), and 7.4% of them had low physical activity. More than 6% were overweight or obese (BMI ≥25kg/m2) and 10% had hypertension (blood pressure ≥140/ 90 mmHg or medication). Capillary blood measurement and history of medication combined provided a prevalence of 3.1% for diabetes while prevalence of hypercholesterolemia (≥240 mg/dL) was 2.9% based on capillary blood cholesterol level alone. Less than half of hypertensive and less than one-tenth diabetes subjects were receiving treatmentfor their respective conditions.Conclusions: Prevalence of noncommunicable diseases risk factorsis fairly high even in thisruralBangladeshi sample. Treatment rate for hypertension and diabetes is quite low. Interventionsshould address lifestyle changes and treatment of diabetes and hypertension.Cardiovasc. j. 2018; 10(2): 126-134

CAPILLARY THINNING AND HIGH CAPILLARY BLOOD-PRESSURE IN HYPERTENSION

The Lancet ◽  
1957 ◽  
Vol 269 (6983) ◽  
pp. 1327-1330 ◽  
Author(s):  
Jacob Landau ◽  
Eli Davis
Keyword(s):  
Blood Pressure ◽  
Capillary Blood ◽  
Capillary Thinning

scholarly journals Resting nailfold capillary blood flow in primary open-angle glaucoma

2018 ◽  
Vol 103 (2) ◽  
pp. 203-207 ◽  
Author(s):  
Clara C Cousins ◽  
Jonathan C Chou ◽  
Scott H Greenstein ◽  
Stacey C Brauner ◽  
Lucy Q Shen ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Blood Flow ◽  
Beta Blocker ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Vessel Diameter ◽  
Ocular Blood Flow ◽  
Capillary Blood ◽  
Capillary Blood Flow ◽  
Open Angle

Background/AimsAn altered haemodynamic profile for various ocular posterior segment capillary beds has been documented in primary open-angle glaucoma (POAG). POAG may also involve abnormal non-ocular blood flow, and the nailfold capillaries, which are not affected by elevated intraocular pressure (IOP), are readily assessable.MethodsWe measured resting nailfold capillary blood flow in 67 POAG and 63 control subjects using video capillaroscopy. Masked readers tracked blood column voids between consecutive, registered image sequence frames, measured vessel diameter and calculated blood flow. We used multiple logistic regression to investigate the relation between nailfold capillary blood flow and POAG. In secondary analyses, we stratified cases by maximum IOP and concurrent topical beta-blocker use.ResultsMean (±SD) blood flow in picolitres per second was 26.8±17.6 for POAG cases and 50.1±24.2 for controls (p<0.0001). After adjustment for demographic and clinical factors including blood pressure and pulse, every picolitre per second increase in resting nailfold blood flow was associated with a 6% (95% CI 0.92 to 0.96) reduced odds of POAG (p<0.0001). Similar relations between nailfold capillary blood flow and POAG were found for cases stratified by maximum known IOP and for cases stratified by concurrent topical beta-blocker use.ConclusionReduced resting nailfold capillary blood flow is present in POAG independent of covariates such as blood pressure, pulse and IOP.

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