HIV-2 in Rhesus Monkeys: Five-Year Follow-Up

2015 ◽  
pp. 95-107
Author(s):  
Isabelle Nicol-Jourdain ◽  
Fran�ois Boussin ◽  
Marie-H�l�ne Bayon-Auboyer ◽  
Guillaume Vogt ◽  
Isabelle Fossati ◽  
...  
Keyword(s):  
Rhesus Monkeys

scholarly journals Mammary Nodular Hyperplasia in Intact Rhesus Monkeys

1973 ◽  
Vol 10 (2) ◽  
pp. 130-134 ◽  
Author(s):  
L. W. Nelson ◽  
L. D. Shott
Keyword(s):  
Focal Nodular Hyperplasia ◽  
Rhesus Monkeys ◽  
Clinical Change ◽  
Control Female ◽  
Subcutaneous Nodules ◽  
Female Rhesus ◽  
Nodular Hyperplasia ◽  
Well Differentiated

Two control female Rhesus monkeys in long-term toxicity studies had multiple, palpable nodules in the breast regions. These subcutaneous nodules were 2–7 mm in diameter, firm, and freely movable. No progressive clinical change was observed during a follow-up of 17 or 20 months. Microscopically, one excised nodule consisted of proliferated acinar epithelial cells arranged in lobular patterns. The cells were well differentiated and presented no features of neoplasia. A diagnosis of focal nodular hyperplasia was compatible with the microscopie findings and the clinical follow-up of similar nodules.

Long-Term Effects of Total Social Isolation Upon Behavior of Rhesus Monkeys

1966 ◽  
Vol 18 (2) ◽  
pp. 567-580 ◽  
Author(s):  
G. D. Mitchell ◽  
E. J. Raymond ◽  
G. C. Ruppenthal ◽  
H. F. Harlow
Keyword(s):  
Social Behavior ◽  
Social Isolation ◽  
Rhesus Monkeys ◽  
First Year ◽  
Long Term Effects ◽  
Negative Effects ◽  
Cross Sectional ◽  
Follow Up Study

8 isolate monkeys were compared in a follow-up study to 8 sophisticated controls in brief cross-sectional pairings with 12 stimulus strangers: 4 adults, 4 age-mates, and 4 juveniles. The isolates were characterized by infantile disturbance, less environmental orality, more fear, more aggression, less sex, less play, and bizarre ritualistic movements. 12-mo. isolates were fearful and nonaggressive but threatened many attacks. 6-mo. isolates were fearful and physically aggressive. The 12-mo. isolates demonstrated practically no positive social behavior. Conclusions are: (a) 6 mo. of social isolation during the first year has negative effects on social behavior up to puberty, (b) abnormal aggression appears in 3-yr.-old 6-mo. isolates, and (c) 12 mo. of isolation suppress or delay this aggression.

Acute occlusion of the posterior spinal vein

1979 ◽  
Vol 51 (2) ◽  
pp. 201-205 ◽  
Author(s):  
John L. Doppman ◽  
Mary Girton ◽  
Mark A. Popovsky
Keyword(s):  
Rhesus Monkeys ◽  
Venous System ◽  
Venous Obstruction ◽  
Venous Outflow ◽  
Content Type ◽  
Acute Occlusion ◽  
Neurological Findings ◽  
Fine Print

✓ The posterior spinal vein was occluded with silicone in seven rhesus monkeys, and locally resected in one. There were no neurological findings associated with acute venous obstruction of the cord. Follow-up arteriography revealed diversion of venous outflow into the anterior spinal venous system. Histology revealed gliosis associated with demyelinization confined to the posterior columns.

Central Versus Peripheral Origin of Vestibuloocular Reflex Recovery Following Semicircular Canal Plugging in Rhesus Monkeys

2000 ◽  
Vol 84 (6) ◽  
pp. 3078-3082 ◽  
Author(s):  
Bernhard J. M. Hess ◽  
Anna Lysakowski ◽  
Lloyd B. Minor ◽  
Dora E. Angelaki
Keyword(s):  
Semicircular Canal ◽  
Rhesus Monkeys ◽  
Semicircular Canals ◽  
Vestibuloocular Reflex ◽  
Head Acceleration ◽  
Significant Recovery ◽  
Sinusoidal Oscillations ◽  
Vertical Semicircular Canals ◽  
Peripheral Origin

We have previously shown that there is a slowly progressing, frequency-specific recovery of the gain and phase of the horizontal vestibuloocular reflex (VOR) in rhesus monkeys following plugging of the lateral semicircular canals. The adapted VOR response exhibited both dynamic and spatial characteristics that were distinctly different from responses in intact animals. To discriminate between adaptation or recovery of central versus peripheral origin, we have tested the recovered vestibuloocular responses in three rhesus monkeys in which either one or both coplanar pairs of vertical semicircular canals had been plugged previously by occluding the remaining semicircular canals in a second plugging operation. We measured the spatial tuning of the VOR in two or three different mutually orthogonal planes in response to sinusoidal oscillations (1.1 Hz, ±5°, ±35°/s) over a period of 2–3 and 12–14 mo after each operation. Apart from a significant recovery of the torsional/vertical VOR following the first operation we found that these recovered responses were preserved following the second operation, whereas the responses from the newly operated semicircular canals disappeared acutely as expected. In the follow-up period of up to 3 mo after the second operation, responses from the last operated canals showed recovery in two of three animals, whereas the previously recovered responses persisted. The results suggest that VOR recovery following plugging may depend on a regained residual sensitivity of the plugged semicircular canals to angular head acceleration.

Therapy and prevention for mental health: What if mental diseases are mostly not brain disorders?

2019 ◽  
Vol 42 ◽  
Author(s):  
John P. A. Ioannidis
Keyword(s):  
Mental Health ◽  
Mental Disease ◽  
Brain Disorders ◽  
Social Stressors ◽  
Labor Education ◽  
Mental Diseases ◽  
Long Term Follow Up ◽  
Political Decisions

AbstractNeurobiology-based interventions for mental diseases and searches for useful biomarkers of treatment response have largely failed. Clinical trials should assess interventions related to environmental and social stressors, with long-term follow-up; social rather than biological endpoints; personalized outcomes; and suitable cluster, adaptive, and n-of-1 designs. Labor, education, financial, and other social/political decisions should be evaluated for their impacts on mental disease.

Brief summary of Kleť photographic search programme for minor planets

1999 ◽  
Vol 173 ◽  
pp. 189-192
Author(s):  
J. Tichá ◽  
M. Tichý ◽  
Z. Moravec
Keyword(s):  
Ccd Camera ◽  
Minor Planet ◽  
Minor Planets ◽  
Main Belt

AbstractA long-term photographic search programme for minor planets was begun at the Kleť Observatory at the end of seventies using a 0.63-m Maksutov telescope, but with insufficient respect for long-arc follow-up astrometry. More than two thousand provisional designations were given to new Kleť discoveries. Since 1993 targeted follow-up astrometry of Kleť candidates has been performed with a 0.57-m reflector equipped with a CCD camera, and reliable orbits for many previous Kleť discoveries have been determined. The photographic programme results in more than 350 numbered minor planets credited to Kleť, one of the world's most prolific discovery sites. Nearly 50 per cent of them were numbered as a consequence of CCD follow-up observations since 1994.This brief summary describes the results of this Kleť photographic minor planet survey between 1977 and 1996. The majority of the Kleť photographic discoveries are main belt asteroids, but two Amor type asteroids and one Trojan have been found.

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