Contrast Media Nephrotoxicity: Urinary Protein and Enzyme Pattern in Patients with or without Saline Infusion during Digital Subtracting Angiography

2015 ◽  
pp. 251-254 ◽  
Author(s):  
M. Carraro ◽  
F. Stacul ◽  
P. Collari ◽  
D. Toson ◽  
F. Zucconi ◽  
...  
Keyword(s):  
Contrast Media ◽  
Urinary Protein ◽  
Saline Infusion ◽  
Enzyme Pattern

scholarly journals Effect of iodinated water soluble contrast media on urinary protein assays.

BMJ ◽  
1992 ◽  
Vol 305 (6844) ◽  
pp. 29-29 ◽  
Author(s):  
S. K. Morcos ◽  
A. M. el-Nahas ◽  
P. Brown ◽  
J. Haylor
Keyword(s):  
Contrast Media ◽  
Urinary Protein ◽  
Water Soluble ◽  
Water Soluble Contrast ◽  
Protein Assays

Urinary Protein Excretion following Intravenously Administered Ionic and Non-Ionic Contrast Media in Man

1989 ◽  
Vol 30 (5) ◽  
pp. 517-519 ◽  
Author(s):  
N. Skovgaard ◽  
J. Holm ◽  
L. Hemmingsen ◽  
P. Skaarup
Keyword(s):  
Renal Function ◽  
Contrast Media ◽  
Urinary Excretion ◽  
Normal Renal Function ◽  
Binding Protein ◽  
Protein A ◽  
Urinary Protein Excretion ◽  
Urinary Protein ◽  
Protein Excretion ◽  
Proximal Tubular

Urinary protein excretion following intravenous administration of the radiographic contrast media (CM) diatrizoate (ionic) and iopromide (non-ionic) was examined in 20 patients with normal renal function. Neither of the two CM had any effect on the 24-h urinary excretion of albumin (a marker of glomerular proteinuria). The 24-h urinary excretion of the retinol-binding protein (a marker of low molecular weight or tubular proteinuria) and the folate binding protein, a protein localized in the brush-border membranes of the proximal tubular cells, showed a statistically significant transient increase the day after diatrizoate injection, whereas no increase was observed after iopromide. Thus, only a minimal and temporary disturbance of the renal proximal tubular function was observed after diatrizoate injection in patients with normal renal function.

Renal Effects of Bicarbonate Versus Saline Infusion for Iso- and Lowosmolar Contrast Media in Rats

2011 ◽  
Vol 46 (11) ◽  
pp. 672-677 ◽  
Author(s):  
Mechthild Ladwig ◽  
Bert Flemming ◽  
Erdmann Seeliger ◽  
Lilit Sargsyan ◽  
Pontus B. Persson
Keyword(s):  
Contrast Media ◽  
Saline Infusion ◽  
Renal Effects

Urinary Protein Excretion following Intravenously Administered Ionic and Non-Ionic Contrast Media in Man

1989 ◽  
Vol 30 (5) ◽  
pp. 517-519 ◽  
Author(s):  
Niels Skovgaard ◽  
J. Holm ◽  
L. Hemmingsen ◽  
P. Skaarup
Keyword(s):  
Contrast Media ◽  
Urinary Protein Excretion ◽  
Urinary Protein ◽  
Protein Excretion ◽  
Ionic Contrast

Post saline infusion test aldosterone levels indicate severity and outcome in primary aldosteronism

2014 ◽  
Vol 122 (03) ◽  
Author(s):  
M Weigel ◽  
A Riester ◽  
G Hanslik ◽  
K Lang ◽  
S Endres ◽  
...  
Keyword(s):  
Primary Aldosteronism ◽  
Saline Infusion ◽  
Infusion Test

Scintigraphic Cholecystography — the Problem of Contrast Media Selection and Labelling

1972 ◽  
Vol 11 (03) ◽  
pp. 265-269
Author(s):  
P. Strohal ◽  
D. Huljev ◽  
K. Filjak ◽  
D. Cvrtila ◽  
Š. Spaventi
Keyword(s):  
Contrast Media ◽  
Media Selection ◽  
Nous Pouvons

La possibilité d’obtenir „Biligraphine“ marquée par 131I d’une activité hautement spécifique a été examinée en vue d’obtenir une préparation convenable pour le diagnostic scintigraphique du tract hépato-biliaire avec l’emploi d’un volume réduit du moyen de contraste.Les résultats ont montré que la meilleure contribution de la réaction est obtenue quand le matériel est traité pendant 11 heures à une température de 150—180° C. Après cette période environ 90% de 131I est entré dans le Biligraphine. Le reste de l’iodide radioactif libre s’élimine por un échangeur d’ions.Nous pouvons conclure que la méthode de l’échange homogène offre de bonnes possibilités pour le marquage des moyens de contraste et qu’elle est réalisable par un procédé relativement simple.

No Evidence for Short-Term Regulation of Plasminogen Activator Inhibitor Activity by Insulin in Man

1992 ◽  
Vol 67 (01) ◽  
pp. 117-120 ◽  
Author(s):  
Helena Vuorinen-Markkola ◽  
llpo Puhakainen ◽  
Hannele Yki-Järvinen
Keyword(s):  
Plasminogen Activator ◽  
Plasma Glucose ◽  
Serum Triglyceride ◽  
Plasminogen Activator Inhibitor ◽  
Saline Infusion ◽  
Serum Triglycerides ◽  
Serum Free ◽  
Free Insulin ◽  
Activator Inhibitor ◽  
Pai 1

SummaryIn crossectional studies a positive correlation has been found between circulating insulin, triglycerides and plasminogen activator inhibitor (PAI-1) activity. To directly examine the effect of insulin on PAI-1 activity in vivo, we determined the response of PAI-1 activity in 17 normal subjects to acute hyperinsulinemia (serum free insulin 92 ± 8 mU/l) during maintenance of normoglycemia (plasma glucose 5.1 ± 0.1 mmol/l). In 12 matched control subjects PAI-1 activity was measured during infusion of saline (serum free insulin 3.6 ± 0.3 mU/l, plasma glucose 5.2 ± 0.1 mmol/l). Plasma PAI-1 activity decreased during the insulin infusion from 9.0 α 1.4 to 5.6 α 0.8 U/ml (p <0.01), and during saline infusion from 7.0 ± 1.4 to 4.3 ± 0.6 U/ml (p <0.05). Serum triglyceride concentrations decreased from 1.09 ± 0.20 to 0.76 ± 0.09 mmol/l (p < 0.001) during hyperinsulinemia but remained unchanged during the saline infusion (1.04 ± 0.11 vs. 1.02 ± 0.12 mmol/l, NS). We conclude that insulin does not acutely change plasma PAI-1 activity, and that acute insulin-induced changes in serum triglycerides occur independently from those of PAI-1 activity.

Ontogenesis of Tissue Plasminogen Activator in the Human

1971 ◽  
Vol 25 (03) ◽  
pp. 469-480 ◽  
Author(s):  
B Åstedt ◽  
M Pandolfi
Keyword(s):  
Plasminogen Activator ◽  
Tissue Plasminogen Activator ◽  
Vena Cava ◽  
Vasa Vasorum ◽  
Moderate Activity ◽  
Foetal Development ◽  
Plasminogen Activator Activity ◽  
Stage Of Development ◽  
Tissue Plasminogen ◽  
Enzyme Pattern

SummaryThe ontogenesis of tissue plasminogen activator in various tissues was studied in 10 embryos and 58 foetuses with a histochemical method.The first appearance of activator activity was seen in a 4-weeks old embryo. At 8-9 weeks it was seen in the eye, meninges, heart, lungs, kidney and vena cava. In the foetal heart high activity was found in the coronary vessels, which can be regarded as the vasa vasorum of the heart. In the lungs a moderate activity increased at 24 weeks of age, when vascularisation increases more rapidly. Intense activity was seen in the highly vascularized corneoscleral junction of the eye later involved in the drainage of aqueous humor.In the kidney the activity could be related to the vessels, while no activity was seen in the glomeruli, the collecting system or the pelvis. In the vessels the activator activity was fairly high. No activity was seen in any stage of development of the liver.The plasminogen activator activity may be of importance for maintaining the foetomaternal circulation and micro-circulation in rapidly growing foetal organs. In the embryo the enzyme pattern is dominated by protein synthetizing enzymes. During foetal development the enzyme pattern changes owing to supervention of enzymes necessary for the function of the various organs. Plasminogen activator belongs to this latter group. The appearance of plasminogen activator activity may therefore be regarded mainly as a sign of functional maturity of the foetal organs.

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