Neonatal Immunity

Faculty Opinions recommendation of Neonatal immunity, respiratory virus infections, and the development of asthma.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.733431379.793546959 ◽

2018 ◽

Author(s):

Achsah Keegan

Keyword(s):

Respiratory Virus ◽

Virus Infections ◽

Neonatal Immunity ◽

Respiratory Virus Infections

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Neonatal Immunity. II. Poliocidal Effects of Human Amniotic Fluids.

Experimental Biology and Medicine ◽

10.3181/00379727-99-24425 ◽

1958 ◽

Vol 99 (3) ◽

pp. 576-579 ◽

Cited By ~ 10

Author(s):

A. J. Steigman ◽

M. M. Lipton

Keyword(s):

Neonatal Immunity

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Current Opinion in Infectious Diseases ◽

10.1097/00001432-198805000-00015 ◽

1988 ◽

Vol 1 (3) ◽

pp. 441-447

Author(s):

S. Strobel

Keyword(s):

Neonatal Immunity

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Vaccinations and Neonatal Immunity

Neonatology ◽

10.1007/978-88-470-1405-3_119 ◽

2012 ◽

pp. 944-948

Author(s):

Alberto G. Ugazio ◽

Alberto E. Tozzi

Keyword(s):

Neonatal Immunity

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Neonatal Immunity

Encyclopedia of Life Sciences ◽

10.1038/npg.els.0000956 ◽

2001 ◽

Author(s):

Denis J Reen

Keyword(s):

Neonatal Immunity

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Group 2 Innate Lymphoid Cells: Central Players in a Recurring Theme of Repair and Regeneration

International Journal of Molecular Sciences ◽

10.3390/ijms21041350 ◽

2020 ◽

Vol 21 (4) ◽

pp. 1350 ◽

Cited By ~ 3

Author(s):

Melina Messing ◽

Sia Cecilia Jan-Abu ◽

Kelly McNagny

Keyword(s):

T Regulatory Cells ◽

Inflammatory Responses ◽

Expression Profiles ◽

Innate Lymphoid Cells ◽

Lymphoid Cells ◽

Helminth Infections ◽

Neonatal Immunity ◽

Group 2 ◽

Transcription Factor Expression

Innate lymphoid cells (ILCs) are recently discovered innate counterparts to the well-established T helper cell subsets and are most abundant at barrier surfaces, where they participate in tissue homeostasis and inflammatory responses against invading pathogens. Group 2 innate lymphoid cells (ILC2s) share cytokine and transcription factor expression profiles with type-2 helper T cells and are primarily associated with immune responses against allergens and helminth infections. Emerging data, however, suggests that ILC2s are also key regulators in other inflammatory settings; both in a beneficial context, such as the establishment of neonatal immunity, tissue repair, and homeostasis, and in the context of pathological tissue damage and disease, such as fibrosis development. This review focuses on the interactions of ILC2s with stromal cells, eosinophils, macrophages, and T regulatory cells that are common to the different settings in which type-2 immunity has been explored. We further discuss how an understanding of these interactions can reveal new avenues of therapeutic tissue regeneration, where the role of ILC2s is yet to be fully established.

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