Vascular Disease and Thrombosis: Relationship to the Antiphospholipid Antibodies

2015 ◽  
pp. 17-25 ◽  
Author(s):  
Ronald A. Asherson ◽  
G. R. V. Hughes
Keyword(s):  
Vascular Disease ◽  
Antiphospholipid Antibodies

Review : Antiphospholipid antibodies and retinal vascular disease

Lupus ◽  
1996 ◽  
Vol 5 (4) ◽  
pp. 313-322 ◽  
Author(s):  
JP Dunn ◽  
SW Noorily ◽  
M. Petri ◽  
D. Finkelstein ◽  
JT Rosenbaum ◽  
...  
Keyword(s):  
Vascular Disease ◽  
Antiphospholipid Antibodies ◽  
Retinal Vascular Disease

Pathophysiology of β2-glycoprotein I in antiphospholipid syndrome

Lupus ◽  
2010 ◽  
Vol 19 (4) ◽  
pp. 379-384 ◽  
Author(s):  
E. Matsuura ◽  
L. Shen ◽  
Y. Matsunami ◽  
N. Quan ◽  
M. Makarova ◽  
...  
Keyword(s):  
Vascular Disease ◽  
Antiphospholipid Syndrome ◽  
Mechanism Of Action ◽  
Antiphospholipid Antibodies ◽  
Physiological Role ◽  
Therapeutic Strategies ◽  
Physiological Functions ◽  
Glycoprotein I ◽  
The Impact

Since β2-glycoprotein I (β2GPI) was described as the major antigenic target for antiphospholipid antibodies, many studies have focused their attention to the physiological role of β2GPI and anti-β2GPI antibodies on autoimmune-mediated thrombosis. Studies reporting the physiological role of β2GPI have been numerous, but the exact mechanism of action(s) has yet to be completely determined. β2GPI’s epitopes for anti-β2GPI autoantibodies have been characterized, however, not all of the heterogeneous anti-β2GPI antibodies are pathogenic. The pathophysiologic role of β2GPI has been reported in the fields of coagulation, fibrinolysis, angiogenesis, and atherosclerosis. Our understanding of the impact of β2GPI, its metabolites and autoantibodies to β2GPI on these physiological functions may contribute to the development of better therapeutic strategies to treat and prevent autoimmune-mediated atherothrombotic vascular disease. Lupus (2010) 19, 379—384.

scholarly journals Occlusive ocular vascular disease and antiphospholipid antibodies.

1990 ◽  
Vol 49 (3) ◽  
pp. 203-203 ◽  
Author(s):  
C Tolosa-Vilella ◽  
J Ordi-Ros ◽  
R Jordana-Comajuncosa ◽  
A Selva-O'Callaghan ◽  
M Vilardell-Tarres
Keyword(s):  
Vascular Disease ◽  
Antiphospholipid Antibodies

ANTIPHOSPHOLIPID ANTIBODIES ASSOCIATED WITH RETINAL VASCULAR DISEASE

Retina ◽  
1987 ◽  
Vol 7 (4) ◽  
pp. 215-218 ◽  
Author(s):  
JOSE S. PULIDO ◽  
LISA M. WARD ◽  
GERALD A. FISHMAN ◽  
JAMES A. GOODWIN ◽  
CHRISTOPHER J. FROELICH ◽  
...  
Keyword(s):  
Vascular Disease ◽  
Antiphospholipid Antibodies ◽  
Retinal Vascular Disease

scholarly journals Ischemic vascular disease and antiphospholipid antibodies are associated with HLA-DRB1 *04/*13 alleles in systemic lupus erythematosus

2012 ◽  
Vol 71 (Suppl 1) ◽  
pp. A57.3-A58
Author(s):  
Elisabet Svenungsson ◽  
Emeli Lundström ◽  
Johanna Gustafsson ◽  
Andreas Jönsen ◽  
Dag Leonard ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Vascular Disease ◽  
Lupus Erythematosus ◽  
Antiphospholipid Antibodies ◽  
Systemic Lupus

HLA-DRB1*04/*13 alleles are associated with vascular disease and antiphospholipid antibodies in systemic lupus erythematosus

2012 ◽  
Vol 72 (6) ◽  
pp. 1018-1025 ◽  
Author(s):  
Emeli Lundström ◽  
Johanna T Gustafsson ◽  
Andreas Jönsen ◽  
Dag Leonard ◽  
Agneta Zickert ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Vascular Disease ◽  
Lupus Erythematosus ◽  
Antiphospholipid Antibodies ◽  
Systemic Lupus
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