The Bioenergetics of Obesity Syndrome

2015 ◽  
pp. 132-170 ◽  
Author(s):  
Julius O. Olowookere
Keyword(s):  
Obesity Syndrome

The Insulin-Obesity Syndrome

1973 ◽  
Vol 138 (2) ◽  
pp. 85-87
Author(s):  
Carl R. Bemiller ◽  
Albert K. Rogers ◽  
Leonard L. Vertuno ◽  
John J. Dempsey
Keyword(s):  
Obesity Syndrome

Molecular Genetics of Obesity Syndrome

Obesity ◽  
2007 ◽  
pp. 115-120
Author(s):  
Atul Sahai ◽  
Rama Dwivedi ◽  
Bernard Mirkin
Keyword(s):  
Molecular Genetics ◽  
Obesity Syndrome ◽  
Genetics Of Obesity

Electrolytic current parameters in the dorsolateral tegmental obesity syndrome in rats

1985 ◽  
Vol 34 (1) ◽  
pp. 57-60 ◽  
Author(s):  
Ronald H. Peters ◽  
Bonnie L. Blythe ◽  
Larry D. Sensenig
Keyword(s):  
Electrolytic Current ◽  
Obesity Syndrome

Adrenalectomy Prevents the Obesity Syndrome Produced by Chronic Central Neuropeptide Y Infusion in Normal Rats

Diabetes ◽  
1997 ◽  
Vol 46 (2) ◽  
pp. 209-214 ◽  
Author(s):  
A. Sainsbury ◽  
I. Cusin ◽  
F. Rohner-Jeanrenaud ◽  
B. Jeanrenaud
Keyword(s):  
Neuropeptide Y ◽  
Obesity Syndrome

scholarly journals Bardet‐Biedl syndrome: Weight patterns and genetics in a rare obesity syndrome

2020 ◽  
Vol 16 (2) ◽  
Author(s):  
Jeremy Pomeroy ◽  
Anthony D. Krentz ◽  
Jesse G. Richardson ◽  
Richard L. Berg ◽  
Jeffrey J. VanWormer ◽  
...  
Keyword(s):  
Bardet Biedl Syndrome ◽  
Obesity Syndrome

Pseudohypoparathyroidism - another monogenic obesity syndrome

2000 ◽  
Vol 52 (3) ◽  
pp. 389-391 ◽  
Author(s):  
Ken K. L. Ong ◽  
Rakesh Amin ◽  
David B. Dunger
Keyword(s):  
Monogenic Obesity ◽  
Obesity Syndrome

scholarly journals Leptin resistance: a prediposing factor for diet-induced obesity

2009 ◽  
Vol 296 (3) ◽  
pp. R493-R500 ◽  
Author(s):  
Philip J. Scarpace ◽  
Yi Zhang
Keyword(s):  
Weight Gain ◽  
Leptin Receptor ◽  
Causative Factor ◽  
Leptin Resistance ◽  
Chow Diet ◽  
High Fat ◽  
Diet Induced Obesity ◽  
Dietary Fructose ◽  
Complex Chronic Disease ◽  
Obesity Syndrome

Obesity is a resilient and complex chronic disease. One potential causative factor in the obesity syndrome is leptin resistance. Leptin behaves as a potent anorexic and energy-enhancing hormone in most young or lean animals, but its effects are diminished or lacking in the obese state associated with a normal genetic background. Emerging evidence suggests that leptin resistance predisposes the animal to exacerbated diet-induced obesity (DIO). Elevation of central leptin in young, lean rats induces a leptin resistance that precludes obesity on a chow diet but accelerates high-fat (HF)-induced obesity. Similarly, chronic dietary fructose consumption evokes a leptin resistance that causes obesity only upon HF exposure. Inherent central leptin insensitivity also contributes to dietary weight gain in certain obesity-prone rats. Conversely, aged, leptin-resistant animals are obese with continuous chow feeding and demonstrate aggravated obesity when challenged with an HF diet. Additionally, a submaximal central blockade with a leptin antagonist leads to obesity on both chow and HF diets, as is the case in rodents with leptin receptor deficiency of genetic origin. Despite the differences in the incidence of obesity on a chow diet, all of these forms of leptin resistance predispose rodents to aggravated HF-mediated obesity. Moreover, once leptin resistance takes hold, it aggravates DIO, and the leptin resistance and obesity compound one another, promoting a vicious cycle of escalating weight gain.

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