Regulatory Peptides in Inflammation, Ulceration, and Tissue Repair: Inflammatory Bowel Disease and Peptic Ulcer Disease1

2015 ◽  
pp. 194-206
Author(s):  
Paul E. Hyman ◽  
Viktor E. Eysselein
Keyword(s):  
Inflammatory Bowel Disease ◽  
Peptic Ulcer ◽  
Bowel Disease ◽  
Tissue Repair ◽  
Regulatory Peptides ◽  
Inflammatory Bowel

scholarly journals ANXIETY, DEPRESSION AND PERSONALITY TYPES IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE: COMPARISONS WITH PEPTIC ULCER AND THE GENERAL POPULATION

2019 ◽  
Author(s):  
Petra ◽  
Emil Babić ◽  
Milenko Bevanda ◽  
Maja Karin ◽  
Mile Volarić ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Peptic Ulcer ◽  
Bowel Disease ◽  
Rating Scale ◽  
Anxiety And Depression ◽  
Control Group ◽  
Ulcer Group ◽  
Inflammatory Bowel ◽  
Anxiety Depression ◽  
Group D

Aim: To explore corellation of anxiety, depression ant type of personality in inflammatory bowel disease (IBD) and compare with peptic ulcer (PU).Subjects and methods: In this study, prevalence of anxiety, depression and type of personality was investigated in 362 cases divided into three groups: 112 of IBD patients, 122 of peptic ulcer patients and 128 of control group who didn't have any gastrointestinal or psychic complaints. IBD and peptic ulcer diagnosis were established by standard diagnostic procedures (anamnesis, clinical manifestations, laboratory, endoscopy and biopsy in IBD and upper endoscopy in peptic ulcer). Anxiety and depression wereestablished by Hamilton anxiety rating scale (HAM-A) and Hamilton rating test for depression (HAM-D). Type of A/B personality was established by Bortner scale and D type of personality by Denollet scale (DS14).Results: Anxiety was found in 47 (41.9%) and depression in 44 (38.3%) of a total of 112 IBD cases. In group with peptic ulcer anxiety was found in 40 (32.8%) and depression aalso in 40 (32.8%) of total 122 cases. In control group anxiety was diagnosed in 21 (16.4%) and depression in 20 (15.6%) of total 128 cases. Anxiety and depresson were significantly higher in both groups than in control group but anxiety and depression were significantly higher in IBD group than peptic ulcer group. D type of personality was statistically significant in peptic ulcer group.Conclusion: Anxiety and depression in IBD and peptic ulcer cases have a greater prevalence compared to the normal population and surprisingly are higher in IBD than peptic ulcer group. D type of personality is associated with peptic ulcer.

scholarly journals Current Topics of the Mechanism of Intestinal Fibrosis in Crohn’s Disease

Immuno ◽  
2021 ◽  
Vol 1 (4) ◽  
pp. 574-582
Author(s):  
Yusuke Honzawa ◽  
Shuji Yamamoto ◽  
Makoto Okabe ◽  
Hiroshi Seno ◽  
Hiroshi Nakase
Keyword(s):  
Inflammatory Bowel Disease ◽  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Detailed Analysis ◽  
Immune Cells ◽  
Bowel Disease ◽  
Tissue Repair ◽  
Inflammatory Process ◽  
Intestinal Fibrosis ◽  
Inflammatory Bowel

Intestinal fibrosis is one of the most common intestinal complications observed in inflammatory bowel disease, especially Crohn’s disease (CD). Intestinal fibrosis in CD is associated with chronic inflammation resulting from immunologic abnormalities and occurs as a form of tissue repair during the anti-inflammatory process. Various types of immune cells and mesenchymal cells, including myofibroblasts, are intricately involved in causing intestinal fibrosis. It is often difficult to treat intestinal fibrosis as intestinal stricture may develop despite treatment aimed at controlling inflammation. Detailed analysis of the pathogenesis of intestinal fibrosis is critical towards advancing the development of future therapeutic applications.

Gastroenterology

2018 ◽  
Author(s):  
Lesley K. Bowker ◽  
James D. Price ◽  
Ku Shah ◽  
Sarah C. Smith
Keyword(s):  
Inflammatory Bowel Disease ◽  
Peptic Ulcer ◽  
Gall Bladder ◽  
Older People ◽  
Enteral Feeding ◽  
Bowel Disease ◽  
Older Patients ◽  
The Elderly ◽  
Ulcer Disease ◽  
Inflammatory Bowel

This chapter provides information on the ageing gastrointestinal system, the elderly mouth, nutrition, enteral feeding, the ethics of clinically assisted feeding, oesophageal disease, dysphagia, peptic ulcer disease, the liver and gall bladder, constipation, diverticular disease, inflammatory bowel disease, diarrhoea in older patients, other colonic conditions, the ‘acute surgical abdomen’, obstructed bowel in older patients, and obesity in older people.

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