A Biochemical Mechanism to Explain Some Characteristics of Overtraining

2015 ◽  
pp. 79-93 ◽  
Author(s):  
E. A. Newsholme ◽  
M. Parry-Billings ◽  
N. McAndrew ◽  
R. Budgett
Keyword(s):  
Biochemical Mechanism

Verification of anoxic phosphate uptake as the main biochemical mechanism of the “dephanox” process

1997 ◽  
Vol 35 (10) ◽  
pp. 87-94 ◽  
Author(s):  
R. Sorm ◽  
J. Wanner ◽  
R. Saltarelli ◽  
G. Bortone ◽  
A. Tilche
Keyword(s):  
Activated Sludge ◽  
Nutrient Removal ◽  
Uptake Rate ◽  
Phosphate Uptake ◽  
Biochemical Mechanism ◽  
Batch Experiments ◽  
Batch Tests ◽  
Genetic Probes ◽  
Activated Sludge Systems ◽  
Removal System

The phenomenon of anoxic phosphate uptake with simultaneous denitrification was studied. For this purpose kinetic batch tests have been carried out by using the activated sludge samples from three modifications of nutrient removal activated sludge systems: two based on an anaerobic-anoxic-oxic (A2/O) system and a third on an anaerobic-oxic (A/O) system. The results showed significant differences in anoxic phosphate uptake rate between activated sludge which was alternatively exposed to anoxic conditions and activated sludge from the A/O arrangement. These differences were also accompanied by different denitrification rates. Simultaneously with batch experiments the microscopic observation of activated sludge samples was carried out. Neisser and Gram stained samples showed clear differences in shape, size and distribution of polyphosphate accumulating bacteria between A2/O and A/O Processes. Moreover, experiments performed using genetic probes confirmed the differences in microbiological composition of activated sludge samples from different nutrient removal system arrangements.

Apoptotic Effects of N-(2-hydroxyphenyl)-2-propylpentanamide on U87-MG and U-2 OS Cells and Antiangiogenic Properties

2020 ◽  
Vol 20 ◽  
Author(s):  
Paola Castillo-Juárez ◽  
Sebastián C. Sanchez ◽  
Alma D. Chávez-Blanco ◽  
Humberto Mendoza-Figueroa ◽  
José Correa-Basurto
Keyword(s):  
Cell Line ◽  
Cell Lines ◽  
Cancer Cell ◽  
Histone Deacetylases ◽  
Biochemical Mechanism ◽  
Antiproliferative Effects ◽  
Human Osteosarcoma ◽  
Antiproliferative Agent ◽  
Induced Apoptosis ◽  
Apoptotic Effects

Background and Objective: Histone deacetylases (HDACs) are important therapeutic targets for many types of human cancers. A derivative of valproic acid, N-(2-hydroxyphenyl)-2-propylpentanamide (HO-AAVPA), has antiproliferative properties on some cancer cell lines and inhibits the HDAC1 isoform. Materials and Methods: In this work, HO-AAVPA was tested as an antiproliferative agent in U87-MG (human glioblastoma) and U-2 OS cells (human osteosarcoma), which are types of cancer that are difficult to treat, and its antiangiogenic properties were explored. Results: HO-AAVPA had antiproliferative effects at 48 h with an IC50 = 0.655 mM in U87-MG cells and an IC50 = 0.453 mM in U-2 OS cells. Additionally, in the colony formation assay, HO-AAVPA decreased the number of colonies by approximately 99% in both cell lines and induced apoptosis by 31.3% in the U-2 OS cell line and by 78.2% in the U87-MG cell line. Additionally, HO-AAVPA reduced the number of vessels in chorioallantoid membranes (CAMs) by approximately 67.74% and IL-6 levels in both cell lines suggesting that the biochemical mechanism on cancer cell of HO-AAVPA is different compared to VPA. Conclusion: HO-AAVPA has antiproliferative effects on glioblastoma and osteosarcoma and antiangiogenic properties.

A proposed biochemical mechanism involving hemoglobin for blast overpressure-induced injury

Toxicology ◽  
1997 ◽  
Vol 121 (1) ◽  
pp. 81-90 ◽  
Author(s):  
Nabil M. Elsayed ◽  
Nikolai V. Gorbunov ◽  
Valerian E. Kagan
Keyword(s):  
Biochemical Mechanism ◽  
Blast Overpressure

The phytochromes: A biochemical mechanism of signaling in sight?

BioEssays ◽  
1997 ◽  
Vol 19 (7) ◽  
pp. 571-579 ◽  
Author(s):  
Peter H. Quail
Keyword(s):  
Biochemical Mechanism

scholarly journals Biochemical Mechanism on GABA Accumulation During Fruit Development in Tomato

2008 ◽  
Vol 49 (9) ◽  
pp. 1378-1389 ◽  
Author(s):  
Takashi Akihiro ◽  
Satoshi Koike ◽  
Ryoji Tani ◽  
Takehiro Tominaga ◽  
Shin Watanabe ◽  
...  
Keyword(s):  
Fruit Development ◽  
Biochemical Mechanism ◽  
Gaba Accumulation

Oxidative damage: The biochemical mechanism of cellular injury and necrosis in choline deficiency

2010 ◽  
Vol 88 (1) ◽  
pp. 143-149 ◽  
Author(s):  
Marisa G. Repetto ◽  
Georgina Ossani ◽  
Alberto J. Monserrat ◽  
Alberto Boveris
Keyword(s):  
Oxidative Damage ◽  
Cellular Injury ◽  
Biochemical Mechanism ◽  
Choline Deficiency

Use of Bacillus velezensis SDTB022 against tobacco black shank (TBS) and the biochemical mechanism involved

2021 ◽  
pp. 104785
Author(s):  
Yue Qiu ◽  
Hao-Hao Yan ◽  
Shou-Min Sun ◽  
Yong-Qiang Wang ◽  
Xue-Ru Zhao ◽  
...  
Keyword(s):  
Biochemical Mechanism ◽  
Bacillus Velezensis ◽  
Black Shank ◽  
Tobacco Black Shank

Biophysical and biochemical mechanism influencing shoot and fruit borer tolerance in brinjal genotypes

2021 ◽  
Vol 78 (3) ◽  
pp. 251-257
Author(s):  
Pankaj Kumar Parveen ◽  
Tamoghna Saha ◽  
Nithya Chandran
Keyword(s):  
Biochemical Mechanism ◽  
Fruit Borer
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