Heme Synthesis in Protoporphyria1

2015 ◽  
pp. 135-147 ◽  
Author(s):  
Joseph R. Bloomer ◽  
Hazel D. Hill ◽  
Ann M. Kools ◽  
James G. Straka
Keyword(s):  
Heme Synthesis

scholarly journals The Effect of Erythropoietin upon Heme Synthesis by Marrow Cells in Vitro

1963 ◽  
Vol 238 (12) ◽  
pp. 4085-4090
Author(s):  
S.B. Krantz ◽  
O. Gallien-Lartigue ◽  
Eugene Goldwasser
Keyword(s):  
Heme Synthesis ◽  
Marrow Cells

scholarly journals Hemin reversal of benzene-induced inhibition of reticulocyte protein synthesis

Blood ◽  
1976 ◽  
Vol 47 (1) ◽  
pp. 145-154 ◽  
Author(s):  
FJ Forte ◽  
HS Cohen ◽  
J Rosman ◽  
ML Freedman
Keyword(s):  
Protein Synthesis ◽  
Sickle Cell ◽  
Clinical Implications ◽  
Intact Cells ◽  
Free Protein ◽  
Translational Repressor ◽  
Heme Synthesis ◽  
Dependent Site ◽  
Cell Free Protein Synthesis ◽  
Rabbit Reticulocytes

Abstract Benzene (0.056–0.113 M) rapidly and reversibly inhibited protein synthesis in anucleate human sickle cell and rabbit reticulocytes. Hemin (50 muM) both prevented and reversed this effect of benzene. The inhibition in rabbit reticulocytes was accompanied by a conversion of polyribosomal disaggregation required ribosomal movement along mRNA and was also prevented and reversed by 50 muM hemin. Benzene was also shown to inhibit heme synthesis in rabbit reticulocytes while neither ATP nor GSH levels were altered. A translational repressor (HCR) of reticulocyte cell-free protein synthesis was isolated from intact cells incubated with benzene, while no significant amount of HCR was found in cells incubated with both benzene and hemin. These results indicated that benzene inhibits translation at the heme-dependent site of initiation. The clinical implications of these experiments remain to be elucidated.

scholarly journals A Review of Bacteriochlorophyllides: Chemical Structures and Applications

Molecules ◽  
2021 ◽  
Vol 26 (5) ◽  
pp. 1293
Author(s):  
Chih-Hui Yang ◽  
Keng-Shiang Huang ◽  
Yi-Ting Wang ◽  
Jei-Fu Shaw
Keyword(s):  
Solar Cell ◽  
Energy Harvesting ◽  
Chemical Structure ◽  
The Other ◽  
Dye Sensitized Solar Cell ◽  
Synthetic Route ◽  
Chemical Structures ◽  
Dye Sensitized ◽  
Heme Synthesis ◽  
Potential Applications

Generally, bacteriochlorophyllides were responsible for the photosynthesis in bacteria. Seven types of bacteriochlorophyllides have been disclosed. Bacteriochlorophyllides a/b/g could be synthesized from divinyl chlorophyllide a. The other bacteriochlorophyllides c/d/e/f could be synthesized from chlorophyllide a. The chemical structure and synthetic route of bacteriochlorophyllides were summarized in this review. Furthermore, the potential applications of bacteriochlorophyllides in photosensitizers, immunosensors, influence on bacteriochlorophyll aggregation, dye-sensitized solar cell, heme synthesis and for light energy harvesting simulation were discussed.

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