Comparison between Calculated O2 Saturation Values and Those Determined Directly In Vitro (Blood Gas Analyzer vs. Oxymeter)

2015 ◽  
pp. 124-129
Author(s):  
R. Zander
2009 ◽  
Vol 32 (8) ◽  
pp. 482-491 ◽  
Author(s):  
HÉLÈNE Morel ◽  
Michel Y. Jaffrin ◽  
Patrick Paullier ◽  
CÉCILE Legallais

This paper proposes an in vitro hemodiafiltration (HDF) model in which the patient is represented by a 2 L bag of fresh heparinized bovine blood circulated by a 4008H monitor through a 0.6 m2 hemodialyzer to investigate kinetics of bicarbonate (HCO3-) during online post-dilution HDF. Five tests were carried out, with three ultrafiltration rates, zero (HD test), 30 and 50 ml/min. Blood gases, pH, HCO3- hematocrit and electrolytes were measured with an ABL77 (Radiometer) blood gas analyzer, and HCO3- was simultaneously measured with a biochemistry analyzer. The variation over time of plasma HCO3- concentrations was also calculated using mass conservation and the model of Legallais et al (JMS 168, 2000, 3–15). Agreement between theoretical and measured concentrations was good during the first 25 minutes of each test, corresponding to the time necessary to dialyze the blood. In hemodialysis (HD), there was an HCO3- mass transfer into blood through the membrane due to diffusion which vanished after 40 minutes, while in HDF tests, blood lost HCO3- due to ultrafiltration after 10 minutes. With reinjection, the net HCO3- mass flow rate to the “patient” decayed, from 1.8 mmol/min at t=0 to zero at the end of the test (t=60 min), and was higher in HD than in HDF. “Patient” dialysance, taking into account reinjection, was positive in all tests, and decayed from about 110 ml/min to 40 ml/min at the end of dialysis. These data confirmed that online HDF automatically corrects acidosis without creating alkalosis when HCO3- dialysate concentration is around 30 mmol/L.


1973 ◽  
Vol 19 (11) ◽  
pp. 1243-1247 ◽  
Author(s):  
P A Drinker ◽  
D C Noonan ◽  
N Ramanaiah ◽  
J R Tole

Abstract Two different blood-gas analyzers were tested to determine the effects on blood pH measurement of changing the reference bridge solution from saturated KCl to normal saline (0.16 mol of NaCl per liter). This change, which necessitated the preparation of modified buffers equimolal in NaCl with respect to blood, virtually eliminated salt depletion of the bridge solution and improved the stability of the liquid-junction potential between the bridge solution and the sample. The instruments we used were the Corning 165 pH Blood Gas Analyzer and the Radiometer E5021 pH Electrode with PHM72 Acid Base Analyzer. Comparison of results on clinical blood samples indicates that performance with the modified bufferbridge system is the same as that obtained with the conventional scheme. Analytical performances of the Corning and Radiometer instruments for PO2 and PCO2, as well as for pH, were comparable.


1995 ◽  
Vol 23 (Supplement) ◽  
pp. A37
Author(s):  
Bartholomew Tortella ◽  
Robert Lavery ◽  
James Doran ◽  
John Seigel

2021 ◽  
Vol 0 (0) ◽  
pp. 0-0
Author(s):  
Zhaozhong Kuang ◽  
Xiaolong Zong ◽  
Shuang Xing ◽  
Fuguang Zhao ◽  
Shanshan Guo ◽  
...  

1996 ◽  
Vol 17 (11) ◽  
pp. 737-740 ◽  
Author(s):  
Denise Gravel-Tropper ◽  
Mary Lee Sample ◽  
Catherine Oxley ◽  
Baldwin Toye ◽  
Donald E. Woods ◽  
...  

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