Peripheral Hemodynamics, Blood Viscosity, and the Renin-Angiotensin System in Hemodialysis Patients under Therapy with Recombinant Human Erythropoietin

2015 ◽  
pp. 292-298 ◽  
Author(s):  
H. M. Steffen ◽  
R. Brunner ◽  
R. M�ller ◽  
S. Degenhardt ◽  
M. Pollok ◽  
...  
Keyword(s):  
Blood Viscosity ◽  
Recombinant Human Erythropoietin ◽  
Renin Angiotensin System ◽  
Hemodialysis Patients ◽  
Angiotensin System ◽  
Renin Angiotensin ◽  
Human Erythropoietin ◽  
Peripheral Hemodynamics

Effect of Renin-Angiotensin System Inhibitor on Residual Glomerular Filtration Rate in Hemodialysis Patients

2012 ◽  
Vol 16 (6) ◽  
pp. 554-559 ◽  
Author(s):  
Yoko Itoh ◽  
Tetsuya Fujikawa ◽  
Yoshiyuki Toya ◽  
Hiroshi Mitsuhashi ◽  
Naoyuki Kobayashi ◽  
...  
Keyword(s):  
Glomerular Filtration Rate ◽  
Glomerular Filtration ◽  
Filtration Rate ◽  
Renin Angiotensin System ◽  
Hemodialysis Patients ◽  
Angiotensin System ◽  
Renin Angiotensin

Renin-Angiotensin System Blockade Is Not Associated with Hyperkalemia in Chronic Hemodialysis Patients

Renal Failure ◽  
2009 ◽  
Vol 31 (10) ◽  
pp. 942-945 ◽  
Author(s):  
Hsin-Hung Lin ◽  
Ya-Fei Yang ◽  
Ju-Kuang Chang ◽  
I-Wen Ting ◽  
Huey-Liang Kuo ◽  
...  
Keyword(s):  
Renin Angiotensin System ◽  
Hemodialysis Patients ◽  
Chronic Hemodialysis ◽  
Angiotensin System ◽  
Renin Angiotensin

Influence of recombinant human erythropoietin on blood pressure and tissue renin-angiotensin systems

1991 ◽  
Vol 261 (5) ◽  
pp. E642-E646 ◽  
Author(s):  
P. Eggena ◽  
P. Willsey ◽  
N. Jamgotchian ◽  
L. Truckenbrod ◽  
M. S. Hu ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Recombinant Human Erythropoietin ◽  
Pressure Rise ◽  
Renin Angiotensin System ◽  
Plasma Renin ◽  
Converting Enzyme Inhibitors ◽  
Renin Substrate ◽  
Blood Pressure Elevation ◽  
Renin Angiotensin ◽  
Human Erythropoietin

In humans, blockade of the renin-angiotensin system with angiotensin converting-enzyme inhibitors (ANG CEI) prevents the rise in blood pressure associated with the administration of recombinant human erythropoietin (rhEPO). This study was conducted to determine whether rhEPO elevates blood pressure in normal Wistar rats and whether the renin-ANG system is affected. Groups of 10 rats each were given rhEPO, ANG CEI (enalapril), rhEPO + ANG CEI, or vehicle. Renin and/or renin substrate mRNA was measured in aortas, kidney, and heart; renin activity (PRA), inactive renin, and renin substrate were measured in plasma. rhEPO raised blood pressure in the normal rat without changing the plasma renin system. ANG CEI prevented this blood pressure rise. Renin-specific mRNA was increased by rhEPO in renal tissue, and renin substrate mRNA was significantly elevated in the kidney and aorta. mRNA for renin and renin substrate were not altered in the heart. In both aorta and kidney, a significant correlation was observed between renin substrate mRNA and blood pressure. The data indicate that rhEPO modulates specific tissue renin-ANG systems, which may contribute to blood pressure elevation.

TNF Alpha-308 Genotype and Renin-Angiotensin System in Hemodialysis Patients: An Effect on Inflammatory Cytokine Levels?

2005 ◽  
Vol 29 (2) ◽  
pp. 174-178 ◽  
Author(s):  
Gultekin Genctoy ◽  
Bulent Altun ◽  
Ahmet Alper Kiykim ◽  
Mustafa Arici ◽  
Yunus Erdem ◽  
...  
Keyword(s):  
Inflammatory Cytokine ◽  
Renin Angiotensin System ◽  
Hemodialysis Patients ◽  
Tnf Alpha ◽  
Angiotensin System ◽  
Renin Angiotensin ◽  
Cytokine Levels

Renin-angiotensin system blockade and the risk of hyperkalemia in chronic hemodialysis patients

2002 ◽  
Vol 112 (2) ◽  
pp. 110-114 ◽  
Author(s):  
Greg A Knoll ◽  
Arjun Sahgal ◽  
Rama C Nair ◽  
Janet Graham ◽  
Carl van Walraven ◽  
...  
Keyword(s):  
Renin Angiotensin System ◽  
Hemodialysis Patients ◽  
Chronic Hemodialysis ◽  
Angiotensin System ◽  
Renin Angiotensin
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