Physiological Regulation of Intakes of Carbohydrate, Fat, and Protein

2015 ◽  
pp. 51-60
Author(s):  
Judith S. Stern ◽  
Thomas W. Castonguay ◽  
Quinton R. Rogers
Keyword(s):  
Physiological Regulation

Physiological regulation of ghrelin by nutrient load in lean and obese subjects

2005 ◽  
Vol 113 (S 1) ◽  
Author(s):  
S Petersenn ◽  
B Wallner ◽  
IM Range ◽  
H Tourne ◽  
N Unger ◽  
...  
Keyword(s):  
Nutrient Load ◽  
Physiological Regulation ◽  
Obese Subjects

scholarly journals Distinct regulation of hippocampal neuroplasticity and ciliary genes by corticosteroid receptors

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Karen R. Mifsud ◽  
Clare L. M. Kennedy ◽  
Silvia Salatino ◽  
Eshita Sharma ◽  
Emily M. Price ◽  
...  
Keyword(s):  
Dna Sequences ◽  
Glucocorticoid Receptors ◽  
Acute Stress ◽  
Circadian Variation ◽  
Rna Seq ◽  
Physiological Regulation ◽  
Behavioural Adaptation ◽  
Neuronal Progenitor ◽  
Genome Wide ◽  
Transcriptional Changes

AbstractGlucocorticoid hormones (GCs) — acting through hippocampal mineralocorticoid receptors (MRs) and glucocorticoid receptors (GRs) — are critical to physiological regulation and behavioural adaptation. We conducted genome-wide MR and GR ChIP-seq and Ribo-Zero RNA-seq studies on rat hippocampus to elucidate MR- and GR-regulated genes under circadian variation or acute stress. In a subset of genes, these physiological conditions resulted in enhanced MR and/or GR binding to DNA sequences and associated transcriptional changes. Binding of MR at a substantial number of sites however remained unchanged. MR and GR binding occur at overlapping as well as distinct loci. Moreover, although the GC response element (GRE) was the predominant motif, the transcription factor recognition site composition within MR and GR binding peaks show marked differences. Pathway analysis uncovered that MR and GR regulate a substantial number of genes involved in synaptic/neuro-plasticity, cell morphology and development, behavior, and neuropsychiatric disorders. We find that MR, not GR, is the predominant receptor binding to >50 ciliary genes; and that MR function is linked to neuronal differentiation and ciliogenesis in human fetal neuronal progenitor cells. These results show that hippocampal MRs and GRs constitutively and dynamically regulate genomic activities underpinning neuronal plasticity and behavioral adaptation to changing environments.

Sharing in the Family System: Contributions of Parental Emotional Expressiveness and Children’s Physiological Regulation

Parenting ◽  
2021 ◽  
pp. 1-25
Author(s):  
Leigha A. MacNeill ◽  
Elizabeth A. Shewark ◽  
Koraly Pérez-Edgar ◽  
Alysia Y. Blandon
Keyword(s):  
Family System ◽  
Emotional Expressiveness ◽  
Physiological Regulation ◽  
The Family

scholarly journals Physiology of guanosine-based second messenger signaling in Bacillus subtilis

2020 ◽  
Vol 401 (12) ◽  
pp. 1307-1322
Author(s):  
Gert Bange ◽  
Patricia Bedrunka
Keyword(s):  
Bacillus Subtilis ◽  
Biofilm Formation ◽  
Second Messengers ◽  
Model Organism ◽  
Physiological Regulation ◽  
Open Questions ◽  
Key Players ◽  
Stress Signals ◽  
Second Messenger Signaling ◽  
Synthesis And Degradation

AbstractThe guanosine-based second messengers (p)ppGpp and c-di-GMP are key players of the physiological regulation of the Gram-positive model organism Bacillus subtilis. Their regulatory spectrum ranges from key metabolic processes over motility to biofilm formation. Here we review our mechanistic knowledge on their synthesis and degradation in response to environmental and stress signals as well as what is known on their cellular effectors and targets. Moreover, we discuss open questions and our gaps in knowledge on these two important second messengers.

scholarly journals Modulation of Cell–Cell Interactions in Drosophila Oocyte Development

Cells ◽  
2020 ◽  
Vol 9 (2) ◽  
pp. 274
Author(s):  
Matthew Antel ◽  
Mayu Inaba
Keyword(s):  
Cell Communication ◽  
Cell Interaction ◽  
Oocyte Development ◽  
Suitable Model ◽  
Physiological Regulation ◽  
Temporal Regulation ◽  
Cellular Processes ◽  
Cellular Machinery ◽  
Drosophila Ovary ◽  
Cell Cell

The Drosophila ovary offers a suitable model system to study the mechanisms that orchestrate diverse cellular processes. Oogenesis starts from asymmetric stem cell division, proper differentiation and the production of fully patterned oocytes equipped with all the maternal information required for embryogenesis. Spatial and temporal regulation of cell-cell interaction is particularly important to fulfill accurate biological outcomes at each step of oocyte development. Progress has been made in understanding diverse cell physiological regulation of signaling. Here we review the roles of specialized cellular machinery in cell-cell communication in different stages of oogenesis.

Control of arterial pressure in aquatic sea snakes

1983 ◽  
Vol 244 (1) ◽  
pp. R66-R73 ◽  
Author(s):  
H. B. Lillywhite ◽  
F. H. Pough
Keyword(s):  
Arterial Pressure ◽  
Blood Volume ◽  
Water Pressure ◽  
Cardiovascular Responses ◽  
Physiological Regulation ◽  
Sea Snakes ◽  
Head Up Tilt ◽  
External Water Pressure ◽  
External Water ◽  
Head Level

Cardiovascular responses to head-up tilt, acutely graded hemorrhage, and pharmacologic stimulation by principal autonomic drugs were studied in four species of marine snakes, principally Aipysurus laevis (family Hydrophiidae). Arterial pressure varied inversely with tilt angle and blood volume deficit in conscious snakes outside of water, indicating that physiological regulation was poor or lacking. Calculated arterial pressures at head level typically diminished to zero in A. laevis tilted to angles greater than or equal to 30 degrees. Arterial pressure (corrected for external water pressure) did not change when these snakes were tilted in seawater. Changes of arterial pressure induced by tilt, blood loss, or autonomic drugs elicited reflex adjustments in heart activity, but the magnitude of these responses was less than that observed in terrestrial species of snake. It is concluded that baroreflexes are present but comparatively ineffective in sea snakes. Snakes tolerated large losses of blood volume, and extravascular fluids were absorbed into the circulation during hemorrhage; both hemorrhage and estimated hemodilution volumes exceeded 100% of the initial blood volume in Acalyptophis peronii. Thus, in marine snakes major fluid shifts between nonvascular and vascular compartments significantly compensate hypovolemia but, because of minor autonomic adjustments, do not result in a well-regulated arterial pressure.

Physiological regulation of P-glycoprotein, MRP1, MRP2 and cytochrome P450 3A2 during rat ontogeny

2003 ◽  
Vol 45 (4) ◽  
pp. 377-387 ◽  
Author(s):  
Anna Rosati ◽  
Silvia Maniori ◽  
Giuliana Decorti ◽  
Luigi Candussio ◽  
Tullio Giraldi ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Physiological Regulation ◽  
P Glycoprotein

scholarly journals Physiological regulation of total tubulin and polymerized tubulin in tissues.

1977 ◽  
Vol 74 (2) ◽  
pp. 351-357 ◽  
Author(s):  
D G Pipeleers ◽  
M A Pipeleers-Marichal ◽  
D M Kipnis
Keyword(s):  
Mouse Liver ◽  
Marked Decrease ◽  
Human Lymphocytes ◽  
Fold Increase ◽  
Human Platelets ◽  
Degree Of Polymerization ◽  
Polymerization Process ◽  
Physiological Factors ◽  
Physiological Regulation ◽  
Tubulin Content

Polymerized and depolymerized forms of tubulin were measured in rat and mouse liver, rat islets, human lymphocytes, and platelets. The percent of the total tubulin present in the polymerized form varied from 30.3 +/- 1.5% in the liver of the fed rat to 89.2 +/- 0.2% in human platelets. Fasting decreased the total tubulin and to a greater extent the polymerized form of tubulin in both rat and mouse liver. Glucose feeding increased the polymerized tubulin without affecting the total tubulin content in rat liver. Phytohemagglutinin-stimulated lymphocytes exhibited at least a three-fold increase in total tubulin (expressed in terms of DNA content), which during the initial 48 h of incubation was accounted for in toto by an increase in polymerized tubulin. It is suggested that the lectin not only accelerates tubulin synthesis but also stimulated the polymerization process. Storage of platelets at 4 degrees C for 6 days resulted in a marked decrease in total tubulin and an even greater reduction in the polymerized form. It is concluded that both the total tubulin content and its degree of polymerization can be modulated independently by a wide variety of physiological factors.

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