Skin Flora of the Normal and Immune Compromised Host

Author(s):  
W. C. Noble
Keyword(s):  
2013 ◽  
Author(s):  
Ramazan Gen ◽  
Elif Sahin Horasan ◽  
Umit Cinkir ◽  
Onur Gultekin ◽  
Esen Akbay
Keyword(s):  

2017 ◽  
Vol 1 (1) ◽  
pp. 67
Author(s):  
Supriyanto Supriyanto ◽  
Indah Purwaningsih

Abstract: Pityriasis versicolor or better known as “panu” is a superfcial fungal infection characterized by changes in skin pigment due to Stratum corneum colonization by dimorphic lipophilic fungi from normal skin flora. Pitiriasis versicolor is an infectious disease that is estimated occur due to poor sanitation (personal hygine) and lack of clean water. This research was aimed to determine factors related to Pityriasis versicolor infection. It used retrospective design where researcher tried to looking back about the incident of Pitiriasis versicolor on 76 fshermen who choosen by using simple random sampling. Based on the result of reseach, it was determine that bath habit (p = 0,000), clothing hygiene (p = 0,839), towels cleanliness (p = 0,699), clean water supply (p = 0,000), home environment hygiene (p = 0,588), for p<0,05 then these factors were related to the occurrence of Pitiriasis versicolor infection on fshermen in Penjajap Village Pemangkat. Thus, it could be conclude that there was signifcant correlation between bath habit and clean water supply with the incidence of Pityriasis versicolor infection. While the cleanliness of clothing, cleanliness of towels, and cleanliness of the home environment is not associated with the incidence of Pityriasis versicolor infection. Abstrak: Pityriasis versikolor atau lebih dikenal dengan panu adalah infeksi jamur superfsial yang ditandai perubahan pigmen kulit akibat kolonisasi stratum korneum oleh jamur lipoflik dimorfk dari flora normal kulit. Pityriasis versikolor merupakan penyakit menular yang diperkirakan terjadi karena sanitasi (personal hygiene) yang buruk dan kurangnya air bersih. Penelitian ini bertujuan untuk mengetahui hubungan faktor-faktor personal hygiene terhadap infeksi pityriasis versikolor. Penelitian ini menggunakan rancangan retrospektif dimana peneliti berusaha melihat ke belakang (backward looking) terhadap kejadian pityriasis versikolor pada 76 nelayan yang terpilih sebagai responden dengan teknik simple random sampling. Berdasarkan hasil penelitian diketahui bahwa kebiasaan mandi (p = 0,000), kebersihan pakaian (p = 0,839), kebersihan handuk (p = 0,699), persediaan air bersih (p = 0,000), kebersihan lingkungan rumah (p = 0,588), untuk p < 0,05 maka faktor-faktor tersebut berhubungan terhadap terjadinya infeksi pityriasis versikolor pada nelayan di Desa Penjajap Kecamatan Pemangkat. Dengan demikian dapat disimpulkan bahwa ada hubungan yang signifkan antara kebiasaan mandi dan persediaan air bersih dengan kejadian infeksi pityriasis versikolor. Sedangkan kebersihan pakaian, kebersihan handuk, dan kebersihan lingkungan rumah tidak berhubungan dengan kejadian infeksi pityriasis versikolor.


1992 ◽  
Vol 20 (4) ◽  
pp. 484-486 ◽  
Author(s):  
J. Brimacombe ◽  
N. Shorney ◽  
R. Swainston ◽  
G. Bapty

The incidence of bacteraemia following insertion of the laryngeal mask airway (LMA) was investigated in one hundred fit patients. Four cultures were positive: three represented contamination with skin flora; the other was a microaerophilic streptococcus grown from an anaerobic culture bottle. Although this organism can be pathogenic, it may also represent contamination. Our findings suggest that significant bacteraemia on insertion of the LMA is uncommon and is probably no more than with oral intubation. Antibiotic prophylaxis is of doubtful benefit in these circumstances.


2020 ◽  
Vol 7 (Supplement_1) ◽  
pp. S187-S187
Author(s):  
Lucy S Tompkins ◽  
Alexandra Madison ◽  
Tammy Schaffner ◽  
Jenny Tran ◽  
Pablito Ang

Abstract Background Blood samples obtained via traditional venipuncture can become contaminated by superficial and deeply embedded skin flora. We evaluated the hospital-wide use of an initial-specimen diversion device (ISDD) designed to shunt these microorganisms away from the culture bottle to reduce blood culture contamination (BCC) and sequelae: false-positive central line-associated bloodstream infections (CLABSIs), repeat blood culture draws, inappropriate antibiotic usage, increased patient length-of-stay and misdiagnosis. The study aimed to show the proportion of blood cultures containing contaminants drawn by phlebotomy staff using the ISDD versus those drawn using traditional methods. Nursing staff continued to use traditional methods to draw blood cultures in the emergency department (ED) and from inpatients. Methods Over a four-month trial at Stanford Health Care (SHC), 4,462 blood cultures were drawn by phlebotomy staff using the ISDD (Steripath Gen2, Magnolia Medical Technologies) in the ED and from inpatients; 922 blood cultures were obtained by phlebotomy staff using standard methods. Additionally, 1,413 blood cultures were drawn by nursing staff using standard methods. The number of matched sets (2 bottles [aerobic/anaerobic] plus 2 bottles [aerobic/anaerobic], with total volume 40 ml) obtained through traditional methods and by the ISDD were recorded. Contaminants were defined by the National Healthcare Safety Network (NHSN). In addition, sets in which 1 out of 4 bottles contained vancomycin-resistant Enterococcus (VRE) or Candida sp. were also recorded, even though these are not considered contaminants by the NHSN. Results Of 4,462 blood cultures obtained using the ISDD there were zero contaminants found (BCC rate 0%) versus 29 contaminated sets using traditional methods (BCC rate 3.15%). Twenty-eight contaminants were observed from nursing staff blood culture draws (BCC rate 1.98%). Zero false-positive CLABSIs were associated with use of the ISDD for the trial period. No matched sets containing 1 of 4 bottles with VRE or Candida sp. were observed. Table Stanford Health Care blood culture collection methods and contamination events (March 15, 2019 - July 21, 2019) Conclusion The trial results encourage adoption of the ISDD as standard practice for blood culture at SHC. Disclosures All Authors: No reported disclosures


Author(s):  
Surinder Kaur M. S. Pada ◽  
Poh Lishi ◽  
Kim Sim Ng ◽  
Sarathamani Rethenam ◽  
Lilibeth Silagan Alenton ◽  
...  

Abstract Background Computerisation of various processes in hospitals and reliance on electronic devices raises the concern of contamination of these devices from the patient environment. We undertook this study to determine if an attached hand hygiene device that unlocks the screen of a computer on wheels (COW) on usage can be effective in decreasing the microbiological burden on computer keyboards. Methods An electronic hand sanitizer was integrated onto the COW. A prospective cohort study with a crossover design involving 2 control and 2 intervention wards was used. The study end point was the number of colony forming units found on the keyboards. Bacteria were classified into 4 main groups; pathogenic, skin flora, from the environment or those thought to be commensals in healthy individuals. We then used a mixed effects model for the statistical analysis to determine if there were any differences before and after the intervention. Results Thirty-nine keyboards were swabbed at baseline, day 7 and 14, with 234 keyboards cultured, colony forming units (CFUs) counted and organisms isolated. By mixed model analysis, the difference of mean bacteria count between intervention and control for week 1 was 32.74 (− 32.74, CI − 94.29 to 28.75, p = 0.29), for week 2 by 155.86 (− 155.86, CI − 227.45 to − 83.53, p < 0.0001), and after the 2-week period by 157.04 (− 157.04, CI − 231.53 to − 82.67, p < 0.0001). In the sub-analysis, there were significant differences of pathogenic bacteria counts for the Intervention as compared to the Control in contrast with commensal counts. Conclusion A hand hygiene device attached to a COW may be effective in decreasing the microbiological burden on computer keyboards.


2012 ◽  
Vol 25 (9) ◽  
pp. 404-408 ◽  
Author(s):  
Dianne Egli-Gany ◽  
Florian H.H. Brill ◽  
Matthias Hintzpeter ◽  
Simone Andrée ◽  
Viktoria Pavel

Chemotherapy ◽  
1981 ◽  
Vol 27 (3) ◽  
pp. 214-219 ◽  
Author(s):  
H. Hof ◽  
P. Emmerling ◽  
H.P.R Seeliger

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