Historical Perspective of Normal Tissue Tolerance or Stumbling Along the Pathway of Dose Response to Necrosis and Back

2015 ◽  
pp. 1-6 ◽  
Author(s):  
William Moss
Keyword(s):  
Dose Response ◽  
Normal Tissue ◽  
Historical Perspective ◽  
Normal Tissue Tolerance

Upper gastrointestinal tract

2019 ◽  
pp. 145-164
Author(s):  
Stephen Falk
Keyword(s):  
Gastrointestinal Tract ◽  
Normal Tissue ◽  
Intensity Modulated Radiotherapy ◽  
Upper Gastrointestinal Tract ◽  
Stereotactic Ablative Radiotherapy ◽  
Normal Tissue Tolerance ◽  
Treatment Techniques ◽  
Gastrointestinal Tumours ◽  
The Uk ◽  
Upper Gastrointestinal

Chapter 7 discusses the upper gastrointestinal tract, and addresses the technical challenges of these cancersin relation to tumour volumes, anatomical situation, and poor normal tissue tolerance, particularly of the intra-abdominal contents. More contemporaneous treatment techniques such as intensity-modulated radiotherapy and stereotactic ablative radiotherapy have not currently made significant impact in the routine treatment of upper gastrointestinal tumours in the UK.

scholarly journals Normal tissue tolerance dose for cervical radiotherapy to the NTCP model using a method of least square fit

2020 ◽  
Vol 12 (1) ◽  
pp. 215-220
Author(s):  
E. Onuh ◽  
A.S. Ajuji ◽  
N. Rabiu ◽  
M.S. Anas ◽  
M. Jada
Keyword(s):  
Normal Tissue ◽  
Normal Tissue Complication Probability ◽  
Least Square ◽  
Planning System ◽  
Radiotherapy Planning ◽  
Treatment Planning System ◽  
Normal Tissue Tolerance ◽  
Tolerance Dose ◽  
Method Of Least Square ◽  
Least Square Fit

The purpose of this study is to evaluate the impact of Normal Tissue Complication Probability (NTCP) models on radiation treatment plans. We estimated NTCP parameters for the organs at risk (OARs) for cervical cancer radiotherapy. We pooled individual patient data from fifty patients who were treated with External Beam Radiotherapy technique between March 2012 and November 2013 in a part of Northern Nigeria with the exclusion of patients who had other gynaecological malignancies. Three basic methods were followed during the radiotherapy planning of these patients which included the pre-planning stage, planning radiotherapy treatment stage and treatment delivery. Various tests were carried out on these patients which helped to confirm the diagnosis after which they were treated using the linear accelerator, computed tomography simulator and the treatment planning system. We calculated the normal tissue tolerance doses for partial volumes of the organs using the values of the above –said parameters for published data on normal tissue tolerance doses. This article shows a graphical representation of the computed NTCP for left femur, right femur and skin presented and a fairly good correspondence is found between the curves for head of femurs and skin. Keywords: Normal Tissue Tolerance Dose, Normal Tissue Complication Probability, Method of Least Square Fit, Cervical Radiotherapy

SU-E-T-711: Normal Tissue Tolerance Evaluation Tool for Clinical Protocols

2013 ◽  
Vol 40 (6Part22) ◽  
pp. 369-370
Author(s):  
S Lee ◽  
H Kim ◽  
S Han ◽  
M Kim ◽  
H Yoo ◽  
...  
Keyword(s):  
Normal Tissue ◽  
Clinical Protocols ◽  
Evaluation Tool ◽  
Normal Tissue Tolerance
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