Comparison of Urinary Enzyme Pattern in Renal Transplant Recipients Receiving Two Different Immunosuppressive Regimens: Azathioprine versus Ciclosporin

2015 ◽  
pp. 203-206 ◽  
Author(s):  
Pasquale Coratelli ◽  
Michele Giannattasio ◽  
Antonio Schena ◽  
Rocco Marzolla ◽  
Erasmo Buongiorno
Keyword(s):  
Renal Transplant ◽  
Renal Transplant Recipients ◽  
Transplant Recipients ◽  
Urinary Enzyme ◽  
Enzyme Pattern

Urinary enzyme excretion by renal-transplant recipients in relation to interval after transplantation.

1982 ◽  
Vol 28 (8) ◽  
pp. 1762-1764 ◽  
Author(s):  
K Jung ◽  
J Diego ◽  
D Scholz ◽  
K Schröder ◽  
V Strobelt
Keyword(s):  
Renal Transplant ◽  
Reference Group ◽  
Transplant Rejection ◽  
Early Period ◽  
Renal Transplant Recipients ◽  
Transplant Recipients ◽  
Renal Disorder ◽  
Urinary Enzyme ◽  
Daily Dose ◽  
Urinary Enzyme Excretion

Abstract We determined the urinary excretion of the enzymes aminopeptidase (EC 3.4.11.2), alkaline phosphatase (EC 3.1.3.1), gamma-glutamyltransferase (EC 2.3.2.2), and N-acetyl-beta-glucosaminidase (EC 3.2.1.30) in two groups of renal-transplant recipients at different times after transplantation (1.8 months and 52 months, respectively). Both groups of patients showed a higher rate of enzyme excretion than did a reference group of healthy persons. More aminopeptidase and N-acetyl-beta-glucosaminidase were excreted during the early period after transplantation than later. The time-dependence of urinary enzyme excretion was confirmed in six renal-transplant recipients studied during the course of 15 months after transplantation. There was a general correlation between the extent of urinary enzyme excretion and both the time after transplantation and the daily dose of prednisolone. Therefore, it is necessary to take into account this influence on the extent of urinary enzyme in renal-transplant recipients if urinary enzyme excretion is used as an indicator of renal disorder and especially as an early predictor of transplant rejection.

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