Quantitative EEG in the Diagnosis and Follow-Up of Alzheimer�s Disease

2015 ◽  
pp. 42-49 ◽  
Author(s):  
Hilkka Soininen ◽  
Juhani V. Partanen
Keyword(s):  
Quantitative Eeg

Quantitative EEG in progressingvsstable mild cognitive impairment (MCI): results of a 1-year follow-up study

2008 ◽  
Vol 23 (11) ◽  
pp. 1148-1155 ◽  
Author(s):  
Christian Luckhaus ◽  
Brigitte Grass-Kapanke ◽  
Ingo Blaeser ◽  
Ralf Ihl ◽  
Tillmann Supprian ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Quantitative Eeg ◽  
Follow Up Study

scholarly journals The clinical use of quantitative EEG in cognitive disorders

2009 ◽  
Vol 3 (3) ◽  
pp. 195-203 ◽  
Author(s):  
Paulo Afonso de Medeiros Kanda ◽  
Renato Anghinah ◽  
Magali Taino Smidth ◽  
Jorge Mario Silva
Keyword(s):  
Background Activity ◽  
Cognitive Disorders ◽  
Quantitative Eeg ◽  
Primary Diagnosis ◽  
Clinical Use ◽  
Ongoing Debate ◽  
Cognitive Dysfunctions ◽  
Follow Up Studies

Abstract The primary diagnosis of most cognitive disorders is clinically based, but the EEG plays a role in evaluating, classifying and following some of these disorders. There is an ongoing debate over routine use of qEEG. Although many findings regarding the clinical use of quantitative EEG are awaiting validation by independent investigators while confirmatory clinical follow-up studies are also needed, qEEG can be cautiously used by a skilled neurophysiologist in cognitive dysfunctions to improve the analysis of background activity, slow/fast focal activity, subtle asymmetries, spikes and waves, as well as in longitudinal follow-ups.

Perampanel Increases Cortical EEG Fast Activity in Child and Adult Patients Affected by Epilepsy: A Quantitative EEG Study

2020 ◽  
pp. 155005942094793
Author(s):  
Claudio Liguori ◽  
Matteo Spanetta ◽  
Francesca Izzi ◽  
Angelo Russo ◽  
Angelo Guerra ◽  
...  
Keyword(s):  
Negative Impact ◽  
Objective Measure ◽  
Quantitative Eeg ◽  
Adult Patients ◽  
Beta Activity ◽  
Cognitive Effects ◽  
Beta Band ◽  
Fast Activity ◽  
Patients With Epilepsy

Objective Quantitative EEG (qEEG) is an established technique used as objective measure for evaluating the effect of antiseizure medications (ASMs) on EEG background activity and monitoring cognitive effects of ASMs. Perampanel (PER) has been associated with relatively more tolerable cognitive effects in patients with epilepsy. The primary aim of the present study was to verify the effect of PER as first add-on ASM on qEEG in child and adult patients affected by epilepsy. The secondary aim of this study was to verify the effectiveness of the drug as first add-on treatment in both child and adult patients with epilepsy. Methods We collected data from 17 adults and 10 children treated with PER as first add-on treatment, who underwent qEEG analysis before starting PER and at 3-month follow-up under stable treatment. Results PER resulted with significant effectiveness in reducing seizures in both children and adults. Considering qEEG analysis, we observed at follow-up the significant increase in beta1 and beta total bands both in children and adult patients. In particular, children showed the significant increase of beta band frequencies predominantly in the occipital regions, whereas adults showed a widespread increase of beta activity. Moreover, we documented in both child and adult patients the global reduction of delta bands activity. Conclusions This qEEG study documented the relative increase of cortical EEG fast activity in both children and adult patients affected by epilepsy and treated by PER. This result may suggest a potential less negative impact of PER on cognition in patients affected by epilepsy, other than demonstrating effectiveness of the drug when used as first add-on treatment in both children and adult patients.

PROSPECTIVE FOLLOW-UP OF CAROTID ENDARTERECTOMY USING QUANTITATIVE EEG AND CEREBRAL CIRCULATION TIME

2009 ◽  
Vol 65 (S90) ◽  
pp. 156-157
Author(s):  
T. Kallanranta ◽  
U. Tolonen ◽  
M. Koskinen ◽  
R. Pokela ◽  
A. Ahonen ◽  
...  
Keyword(s):  
Carotid Endarterectomy ◽  
Cerebral Circulation ◽  
Quantitative Eeg ◽  
Circulation Time ◽  
Cerebral Circulation Time

scholarly journals Quantitative EEG in type 1 diabetic adults with childhood exposure to severe hypoglycaemia: a 16 year follow-up study

Diabetologia ◽  
2011 ◽  
Vol 54 (9) ◽  
pp. 2404-2408 ◽  
Author(s):  
B. O. Åsvold ◽  
T. Sand ◽  
K. A. Hestad ◽  
M. R. Bjørgaas
Keyword(s):  
Severe Hypoglycaemia ◽  
Quantitative Eeg ◽  
Childhood Exposure ◽  
Follow Up Study

Quantitative EEG Neurometric Analysis–Guided Neurofeedback Treatment in Postconcussion Syndrome (PCS): Forty Cases. How Is Neurometric Analysis Important for the Treatment of PCS and as a Biomarker?

2016 ◽  
Vol 48 (3) ◽  
pp. 217-230 ◽  
Author(s):  
Tanju Surmeli ◽  
Emin Eralp ◽  
Ilham Mustafazade ◽  
Ismet Hadi Kos ◽  
Gül Elif Özer ◽  
...  
Keyword(s):  
Minnesota Multiphasic Personality Inventory ◽  
Case Series ◽  
Depression Scale ◽  
Symptom Assessment ◽  
Quantitative Eeg ◽  
Hamilton Depression Scale ◽  
Postconcussion Syndrome ◽  
Residual Symptoms

Postconcussion syndrome (PCS) has been used to describe a range of residual symptoms that persist 12 months or more after the injury, often despite a lack of evidence of brain abnormalities on magnetic resonance imaging and computed tomography scans. In this clinical case series, the efficacy of quantitative EEG–guided neurofeedback in 40 subjects diagnosed with PCS was investigated. Overall improvement was seen in all the primary (Symptom Assessment-45 Questionnaire, Clinical Global Impressions Scale, Hamilton Depression Scale) and secondary measures (Minnesota Multiphasic Personality Inventory, Test of Variables for Attention). The Neuroguide Traumatic Brain Index for the group also showed a decrease. Thirty-nine subjects were followed up long term with an average follow-up length of 3.1 years (CI = 2.7-3.3). All but 2 subjects were stable and were off medication. Overall neurofeedback treatment was shown to be effective in this group of subjects studied.

scholarly journals Slowing on quantitative EEG is associated with transition to dementia in mild cognitive impairment

2021 ◽  
pp. 1-5
Author(s):  
Calum A. Hamilton ◽  
Julia Schumacher ◽  
Fiona Matthews ◽  
John-Paul Taylor ◽  
Louise Allan ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Lewy Bodies ◽  
Quantitative Eeg ◽  
Clinical Progression ◽  
Consensus Panel ◽  
Functional Changes ◽  
Incident Dementia ◽  
Eeg Abnormalities

ABSTRACT Electroencephalographic (EEG) abnormalities are greater in mild cognitive impairment (MCI) with Lewy bodies (MCI-LB) than in MCI due to Alzheimer’s disease (MCI-AD) and may anticipate the onset of dementia. We aimed to assess whether quantitative EEG (qEEG) slowing would predict a higher annual hazard of dementia in MCI across these etiologies. MCI patients (n = 92) and healthy comparators (n = 31) provided qEEG recording and underwent longitudinal clinical and cognitive follow-up. Associations between qEEG slowing, measured by increased theta/alpha ratio, and clinical progression from MCI to dementia were estimated with a multistate transition model to account for death as a competing risk, while controlling for age, cognitive function, and etiology classified by an expert consensus panel. Over a mean follow-up of 1.5 years (SD = 0.5), 14 cases of incident dementia and 5 deaths were observed. Increased theta/alpha ratio on qEEG was associated with increased annual hazard of dementia (hazard ratio = 1.84, 95% CI: 1.01–3.35). This extends previous findings that MCI-LB features early functional changes, showing that qEEG slowing may anticipate the onset of dementia in prospectively identified MCI.

Quantitative EEG During Critical Illness Correlates With Patterns of Long-Term Cognitive Impairment

2020 ◽  
pp. 155005942097800
Author(s):  
Shawniqua Williams Roberson ◽  
Naureen Abdul Azeez ◽  
Randip Taneja ◽  
Brenda T. Pun ◽  
Pratik P. Pandharipande ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Critical Illness ◽  
Quantitative Eeg ◽  
Cognitive Testing ◽  
Alpha Power ◽  
Cognitive Assessments ◽  
Domain Specific ◽  
Eeg Recordings

Objective Many intensive care unit (ICU) survivors suffer disabling long-term cognitive impairment (LTCI) after critical illness. We compared EEG characteristics during critical illness with patients’ 1-year neuropsychological outcomes. Methods We performed a post hoc analysis of patients in the BRAIN-ICU study who had undergone EEG for clinical purposes during admission (n = 10). All survivors underwent formal cognitive assessments at 12-month follow-up. We evaluated EEGs by conventional visual inspection and computed 10 quantitative features. We explored associations between EEG and patterns of LTCI using Wilcoxon rank-sum tests and Spearman’s rank correlations. Results Of 521 Vanderbilt patients enrolled in the parent study, 24 had EEG recordings during admission. Ten survivors had EEG tracings available and completed follow-up cognitive testing. All but one inpatient EEG showed generalized background slowing. All patients demonstrated cognitive impairment in at least one domain at follow-up. The most common deficits occurred in delayed memory (DM—median index 62) and visuospatial/constructional (VC—median index 69) domains. Relative alpha power correlated with VC score (ρ = 0.78, P = .008). Peak interhemispheric coherence correlated negatively with DM (ρ = −0.81, P = .018). Conclusions Quantitative EEG features during critical illness correlated with domain-specific cognitive performance in our small cohort of ICU survivors. Further study in larger prospective cohorts is required to determine whether these relationships hold. Significance EEG may serve as a prognostic biomarker predicting patterns of long-term cognitive impairment.

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