Seroepidemiological Considerations on the Detection of Anti-HIV-1 Antibodies in Hospitalized Patients and Blood Donors from Different Medical Centers in Brazzaville

2015 ◽  
pp. 41-49
Author(s):  
F. Yala ◽  
M. Biendo ◽  
M. C. Samba ◽  
P. Mpele ◽  
B. Carme
Keyword(s):  
Blood Donors ◽  
Hospitalized Patients ◽  
Medical Centers ◽  
Anti Hiv ◽  
Hiv 1

Occurrence of Anti-CMV-, Anti-HIV-1, and HBsAg-Positive Individuals in a Group of Blood Donors and Patients on Chronic Dialysis in Lebanon

1990 ◽  
Vol 10 (4) ◽  
pp. 471-473
Author(s):  
George E. Abdelnour ◽  
Nada H. Khattar ◽  
Alexander M. Abdelnoor
Keyword(s):  
Blood Donors ◽  
Chronic Dialysis ◽  
Anti Hiv ◽  
Hiv 1

scholarly journals Prevalence of and risk factors for HIV infection in blood donors and various population subgroups in Ethiopia

2002 ◽  
Vol 128 (2) ◽  
pp. 221-228 ◽  
Author(s):  
R. E. J. H. SENTJENS ◽  
Y. SISAY ◽  
H. VRIELINK ◽  
D. KEBEDE ◽  
H. J. ADÈR ◽  
...  
Keyword(s):  
Risk Factors ◽  
Hiv Infection ◽  
Sexual Behaviour ◽  
Blood Donors ◽  
Transmitted Disease ◽  
Urban Residents ◽  
Sexual Transmitted Disease ◽  
Low Prevalence ◽  
Anti Hiv ◽  
Hiv 1

The aim was to determine the prevalence of HIV infection and risk factors for HIV infection in various population subgroups in Ethiopia. Serum panels from blood donors (n = 2610), from various population subgroups in Ethiopia were tested for anti-HIV-1/2 by ELISA. All ELISA repeatedly reactive samples were subjected for confirmation by immunoblot (IB) and anti-HIV-1 and anti-HIV-2 specific ELISAs. 155/2610 (5·9%) blood donors were HIV-1 infected. Of pregnant women, 84/797 (10·5%) were HIV-1 infected, and 1/797 (0·1%) was HIV-2 infected. 1/240 (0·4%) individuals from the rural population were HIV-1 infected. 198/480 (41·3%) female attendees, and 106/419 (25·3%) male attendees at sexual transmitted disease (STD) clinics were HIV-1 infected. One (0·2%) male, and 2 (0·4%) female STD patients were infected with both HIV-1 and HIV-2. It was concluded that the prevalence of HIV-1 infection varied from 0·4% among urban residents to 25·3–41·3% among STD attendees. There is a low prevalence of HIV-2 present in Ethiopian subjects. Risky sexual behaviour is significantly associated with HIV-infection in Ethiopia.

Anti-HIV-1 antibodies among young, unpaid blood donors from Goma, Northern Kivu, Zaire

AIDS ◽  
1990 ◽  
Vol 4 (11) ◽  
pp. 1162 ◽  
Author(s):  
Mauro Almaviva ◽  
Kalema Welo ◽  
Winga Maganga ◽  
Kupa Mukengeshay ◽  
Isolina Piccioni ◽  
...  
Keyword(s):  
Blood Donors ◽  
Anti Hiv ◽  
Hiv 1

scholarly journals Multicenter Evaluation of the New Automated Enzymun-Test Anti-HIV 1 + 2 + Subtyp O

1998 ◽  
Vol 36 (2) ◽  
pp. 580-584 ◽  
Author(s):  
Bernard Weber
Keyword(s):  
Human Immunodeficiency Virus ◽  
Blood Donors ◽  
Antibody Detection ◽  
Third Generation ◽  
Antibody Assay ◽  
Immunodeficiency Virus ◽  
International Multicenter Study ◽  
Anti Hiv ◽  
International Multicenter ◽  
Hiv 1

An international multicenter study was performed to evaluate a new, automated human immunodeficiency virus (HIV) third-generation antibody assay. The Enzymun-Test Anti-HIV 1 + 2 + Subtyp O showed 100% sensitivity and 99.8% specificity among 11,172 samples from hospitalized patients and blood donors. For early HIV antibody detection in seroconversion panels, Enzymun-Test showed a sensitivity equivalent to that of the Abbott Recomb. HIV-1/HIV-2 3rd Gen. assay.

Antibody to hepatitis C virus in blood donors found positive for other agents. II. Anti-HIV-1

1991 ◽  
Vol 1 (3) ◽  
pp. 195-197
Author(s):  
M. C. Moore ◽  
J. A. J. Barbara ◽  
P. E. Hewitt
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Blood Donors ◽  
Anti Hiv ◽  
Hiv 1

scholarly journals HBsAg, anti-HCV, anti-HIV 1/2 and syphilis seroprevalence in healthy volunteer blood donors in southeastern Anatolia

2013 ◽  
Vol 7 (09) ◽  
pp. 665-669 ◽  
Author(s):  
Saim Dayan ◽  
Alicem Tekin ◽  
Recep Tekin ◽  
Tuba Dal ◽  
Salih Hoşoğlu ◽  
...  
Keyword(s):  
Healthy Volunteer ◽  
Blood Donors ◽  
Blood Donation ◽  
Treponema Pallidum ◽  
University Hospital ◽  
Virus Surface ◽  
Significant Difference ◽  
Syphilis Screening ◽  
Anti Hiv ◽  
Hiv 1

Introduction: This study investigated the seroprevalence of hepatitis B virus surface antigen (HBsAg), antibody against hepatitis C virus (anti-HCV), antibody against human immunodeficiency virus type 1/2 (anti-HIV 1/2), and antibody against Treponema pallidum (anti-Treponemal or syphilis antibody) in healthy volunteer blood donors, and assessed their distribution according to the years and genders. Methodology: HBsAg, anti-HCV, anti-HIV ½, and syphilis screening results of a total of 266,035 healthy volunteer blood donors who had been admitted for blood donation to the Regional Blood Center of Dicle University Hospital between January 2000 and December 2010 were evaluated, retrospectively. HBsAg, anti-HCV, and anti-HIV 1/2 screening were performed using a fully automated device with the microparticle enzyme immunoassay method (MEIA). Syphilis screening was performed by Rapid Plasma Reagin (RPR) carbon test between January 2000 and December 2009, and by using a fully automated device with the MEIA method between January 2010 and December 2010. Results: Of 266,035 healthy volunteer blood donors, 259,384 (97.5%) were male and 6,651 (2.5%) were female. Statistically, there was not any significant difference between male and female genders for HBsAg, anti-HCV and syphilis seropositivities (P = 0.729, P = 0.748, and P = 0.861, respectively). HBsAg was found to be positive in 8,422 (3.17%), anti-HCV in 1,703 (0.64%), anti-HIV 1/2 in one (0.0004%) of 266,035 healthy volunteer blood donors, and syphilis antibody with RPR in 166 (0.07%) of 246,341 healthy volunteer blood donors. Conclusion: Blood donor forms should be carefully tailored to improve the identification of possible risks of transfusion-transmitted infections.

Monitoring blood donors for HIV-2 infection by testing anti-HIV-1 reactive sera

Transfusion ◽  
1990 ◽  
Vol 30 (2) ◽  
pp. 184-187 ◽  
Author(s):  
MP Busch ◽  
L Petersen ◽  
C Schable ◽  
H Perkins
Keyword(s):  
Blood Donors ◽  
Anti Hiv ◽  
Hiv 1

Anticardiolipin Antibodies Are Elevated in HIV-1 Infected Haemophiliacs but Do Not Predict for Disease Progression

1989 ◽  
Vol 61 (01) ◽  
pp. 081-085 ◽  
Author(s):  
Simon Panzer ◽  
Christoph Stain ◽  
Hubert Hartl ◽  
Robert Dudczak ◽  
Klaus Lechner
Keyword(s):  
Normal Values ◽  
Anticardiolipin Antibodies ◽  
Haemophilia A ◽  
Serum Samples ◽  
Factor Viii Concentrates ◽  
Patient Groups ◽  
Anti Hiv ◽  
Hiv 1 ◽  
Cd4 Lymphocytes

SummaryLevels of anticardiolipin antibodies (ACA) were measured in 55 patients with haemophilia A in serum samples obtained in 1983 and in 1987. Twenty-one patients were negative for anti HIV-1 antibodies in 1983 and remained negative in 1987; 34 patients had anti HIV-1 antibodies in 1983; 17 of these latter patients remained asymptomatic, whereas 17 patients developed ARC or AIDS during the 4 years follow-up. Thirteen anti HIV-1 negative patients had elevated ACA levels in 1983; subsequently, a significant decrease was observed in all these subjects (p <0.001). All anti HIV-1 positive patients had elevated ACA levels in 1983; normal values were found in 9 patients in 1987. Yet, these changes were not significant (p >0.05). ACA levels were significantly higher in HIV-1 infected patients than in those without anti HIV-1 antibodies (p <0.05). There was no difference of ACA levels between the two anti HIV-1 positive patient groups, be it in 1983 or be it in 1987 (p >0.05). There was no correlation of ACA levels with serum IgG concentrations, CD4+ lymphocytes, or the consumption of factor VIII concentrates.

Autoantibodies to Phospholipids and to the Coagulation Proteins in AIDS

1997 ◽  
Vol 77 (05) ◽  
pp. 0856-0861 ◽  
Author(s):  
N Abuaf ◽  
S Laperche ◽  
B Rajoely ◽  
R Carsique ◽  
A Deschamps ◽  
...  
Keyword(s):  
Lupus Erythematosus ◽  
Antiphospholipid Antibodies ◽  
Blood Donors ◽  
Heterogeneous Mixture ◽  
Systemic Lupus ◽  
Hematological Disorders ◽  
False Positive Test ◽  
Glycoprotein I ◽  
Coagulation Proteins ◽  
Hiv 1

SummaryIn HIV-1 infection, an increased prevalence of anticardiolipin autoantibodies (aCL) and lupus anticoagulant (LA) has been described. In order to see if these antibodies are isolated or, like in autoimmune diseases, associated with hematological disorders and with antibodies to other phospholipids and to proteins of coagulation, we investigated 3 groups of patients: 1. 342 HIV-1 infected patients, 2. 145 control patients including 61 systemic lupus erythematosus (SLE) patients, 58 patients with a connective tissue disease, 15 patients with stroke, 11 patients with syphilis and 3.100 blood donors. In HIV-1 infection antiprothrombin (aPrT) antibodies were present in 25% of patients, the prevalence of antiphosphatidylcholine antibodies (aPC) (50%) was almost as high as aCL (64%), and 39% had both antibodies. Absorption on liposomes of the latter revealed an heterogeneous mixture of aCL and aPC or cross-reacting antibodies. In contrast with SLE, anti-β2-glycoprotein I (4%), LA (1%), biological false positive test for syphilis (0.3%), thrombosis (p <0.001) were uncommon. In HIV-1 infection, antiphospholipid antibodies do not associate with features linked to them in SLE or syphilis.

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