Allo-Immune Thrombocytopenias, Definition of a Group at Risk; A Prospective Study1

2015 ◽  
pp. 119-124 ◽  
Author(s):  
M. F. Reznikoff-Etievant ◽  
C. Kaplan ◽  
J. Y. Muller ◽  
F. Daffos ◽  
F. Forestier
Keyword(s):  
At Risk ◽  
Definition Of

scholarly journals Definitions and Concepts for Quantitative Rockfall Hazard and Risk Analysis

Geosciences ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 158
Author(s):  
Didier Hantz ◽  
Jordi Corominas ◽  
Giovanni B. Crosta ◽  
Michel Jaboyedoff
Keyword(s):  
Risk Assessment ◽  
At Risk ◽  
Failure Probability ◽  
Rockfall Hazard ◽  
Process Failure ◽  
Failure Propagation ◽  
Element At Risk ◽  
Hazard And Risk ◽  
Hazard And Risk Assessment ◽  
Definition Of

There is an increasing need for quantitative rockfall hazard and risk assessment that requires a precise definition of the terms and concepts used for this particular type of landslide. This paper suggests using terms that appear to be the most logic and explicit as possible and describes methods to derive some of the main hazards and risk descriptors. The terms and concepts presented concern the rockfall process (failure, propagation, fragmentation, modelling) and the hazard and risk descriptors, distinguishing the cases of localized and diffuse hazards. For a localized hazard, the failure probability of the considered rock compartment in a given period of time has to be assessed, and the probability for a given element at risk to be impacted with a given energy must be derived combining the failure probability, the reach probability, and the exposure of the element. For a diffuse hazard that is characterized by a failure frequency, the number of rockfalls reaching the element at risk per unit of time and with a given energy (passage frequency) can be derived. This frequency is relevant for risk assessment when the element at risk can be damaged several times. If it is not replaced, the probability that it is impacted by at least one rockfall is more relevant.

scholarly journals Neonatal Hypoglycaemia: A Never-Ending Story?

Neonatology ◽  
2021 ◽  
pp. 1-8
Author(s):  
Nestor E. Vain ◽  
Florencia Chiarelli
Keyword(s):  
At Risk ◽  
Neonatal Period ◽  
Newborn Infants ◽  
Neonatal Hypoglycaemia ◽  
Rational Decision Making ◽  
Weak Evidence ◽  
Universal Approach ◽  
Definition Of ◽  
Therapeutic Alternatives ◽  
Current Guidelines

Neonatal hypoglycaemia is a common metabolic disorder presenting in the first days of life and one potentially preventable cause of brain injury. However, a universal approach to diagnosis and management is still lacking. The rapid decrease in blood glucose (BG) after birth triggers homeostatic mechanisms. Most episodes of hypoglycaemia are asymptomatic, and symptoms, when they occur, are nonspecific. Therefore, neonatologists are presented with the challenge of identifying infants at risk who might benefit from a rapid and effective therapy while sparing others unnecessary sampling and overtreatment. There is much controversy regarding the definition of hypoglycaemia, and one level does not fit all infants since postnatal age and clinical situations trigger different accepted thresholds for therapy. The concentration and duration of BG which cause neurological damage are unclear. Recognizing which newborn infants are at risk of hypoglycaemia and establishing protocols for treatment are essential to avoid possible deleterious effects on neurodevelopment. Early breastfeeding may reduce the risk of hypoglycaemia, but in some cases, the amount of breast milk available immediately after birth is insufficient or non-existent. In these situations, other therapeutic alternatives such as oral dextrose gel may lower the risk for NICU admissions. Current guidelines continue to be based on expert opinion and weak evidence. However, malpractice litigation related to neurodevelopmental disorders is frequent in children who suffered hypoglycaemia in the neonatal period even if they had other important factors contributing to the poor outcome. This review is aimed to help the practicing paediatricians and neonatologists to comprehend neonatal hypoglycaemia from physiology to therapy, hoping it will result in a rational decision-making process in an area not sufficiently supported by evidence.

Williamson on Defining Knowledge

Episteme ◽  
2020 ◽  
pp. 1-17
Author(s):  
Manuel Pérez Otero
Keyword(s):  
At Risk ◽  
Mental States ◽  
Definition Of

Abstract In his outstanding book Knowledge and its Limits (2000), Williamson (a) claims that we have inductive evidence for some negative theses concerning the prospects of defining knowledge, like this: knowing cannot be defined in accordance with a determinate traditional conjunctive scheme; (b) defends a theory of mental states, mental concepts and the relations between the two, from which we would obtain additional, not merely inductive, evidence for this negative thesis; and (c) presents an alternative (non-traditional-conjunctive) definition of knowledge. Here I consider these issues and extract two relevant conclusions: (i) Williamson's theory of states and concepts only supports the negative thesis because this theory would explain too much, since it imposes implausible necessary limitations on possible uses of concepts and linguistic expressions. So, there is no appropriate non-inductive evidence for the negative thesis. (ii) Williamson's own definition of knowledge is at risk.

scholarly journals Promotion, prevention and treatment interventions for mental health in low- and middle-income countries through a task-shifting approach

2020 ◽  
Vol 29 ◽  
Author(s):  
Marianna Purgato ◽  
Eleonora Uphoff ◽  
Rakesh Singh ◽  
Ambika Thapa Pachya ◽  
Jibril Abdulmalik ◽  
...  
Keyword(s):  
Mental Health ◽  
At Risk ◽  
Global Mental Health ◽  
Task Shifting ◽  
Treatment Interventions ◽  
Middle Income ◽  
Middle Income Countries ◽  
Prevention And Treatment ◽  
Prevention Interventions ◽  
Definition Of

Abstract Recently, mental health and ill health have been reframed to be seen as a continuum from health to ill health, through the stages of being asymptomatic ‘at risk’, to experiencing ‘mental distress’, ‘sub-syndromal symptoms’ and finally ‘mental disorders’. This new conceptualisation emphasised the importance of mental health promotion and prevention interventions, aimed at reducing the likelihood of future disorders with the general population or with people who are identified as being at risk of a disorder. This concept generated discussion on the distinction between prevention and treatment interventions, especially for those mental health conditions which lie between psychological distress and a formal psychiatric diagnosis. The present editorial aims to clarify the definition of promotion, prevention and treatment interventions delivered through a task-shifting approach according to a global mental health perspective.

Genetic determinants of psychic resilience after a diagnosis of cancer

2017 ◽  
Vol 41 (S1) ◽  
pp. S596-S596
Author(s):  
M. Christensen ◽  
A. Drago
Keyword(s):  
At Risk ◽  
Psychiatric Disorders ◽  
Depressive Disorders ◽  
Adjustment Disorder ◽  
Genetic Determinants ◽  
Co Morbidity ◽  
Patients At Risk ◽  
Diagnosis Of Cancer ◽  
Competing Interest ◽  
Definition Of

IntroductionCo-morbidity between cancer and psychiatric disorders including adjustment disorder, depressive disorders or angst can seriously influence the prognosis and the quality of life of patients.AimThe identification of the psychological and biological profile of patients at risk for such co-morbidity is not yet available. Classical candidate genes such as the BDNF, the 5-HTLPR and genes whose products are involved in inflammatory events have received some attention, but results are inconclusive.Object and methodsIn the present review the association between cancer and psychiatric disorders is reviewed, a focus on the investigation of the Gene X environment and the epigenetic control over the activation of the HPA axis is proposed as a tool to refine the definition of the biologic profile at risk for co-morbidity between psychiatry and cancer.Results and conclusionA number of genes and socio-demographic variables that may influence risk to suffer from a psychiatric disorder after a diagnosis of cancer is identified and discussed. The identification of such biologic and socio-demographic profile is instrumental in the identification of subjects at risk of a double diagnosis, both somatic and psychiatric. An early identification of such profile risk would pave the way to the implementation of early intervention strategies.Disclosure of interestThe authors have not supplied their declaration of competing interest.

The Seveso episode: The validity of epidemiological inquires in relation with the definition of population at risk

Chemosphere ◽  
1986 ◽  
Vol 15 (9-12) ◽  
pp. 1777-1786 ◽  
Author(s):  
Franco Merlo ◽  
Riccardo Puntoni ◽  
Leonardo Santi
Keyword(s):  
At Risk ◽  
Population At Risk ◽  
Definition Of

scholarly journals PO-1006: Evaluation of an auto-segmentation software for definition of organs at risk in radiotherapy

2017 ◽  
Vol 123 ◽  
pp. S554
Author(s):  
M.D. Herraiz Lablanca ◽  
S. Paul ◽  
M. Chiesa ◽  
K.H. Grosser ◽  
W. Harms
Keyword(s):  
At Risk ◽  
Organs At Risk ◽  
Definition Of

The Semantics of State Policy Making: The Case of “At Risk”

1993 ◽  
Vol 15 (4) ◽  
pp. 380-395 ◽  
Author(s):  
Margaret L. Placier
Keyword(s):  
At Risk ◽  
Policy Process ◽  
State Policy ◽  
Policy Making ◽  
Department Of Education ◽  
Cultural Framework ◽  
Policy Construction ◽  
Key Policy ◽  
Definition Of ◽  
Linguistic Framework

Definitions of key policy terms are important elements in policy construction. Accordingly, the power to define such terms is a linguistic marker of relationships among players in the policy process. Combining a linguistic framework with the cultural framework of Marshall, Mitchell, and Wirt (1989), this article traces definition of the term at risk in the context of one state, Arizona. Researchers in the Department of Education used the definition process as an opportunity to enhance the department’s prestige and power in relation to other policy-making bodies.

Sign in / Sign up

Export Citation Format

Share Document