A New Wound Healing Model: Human Skin Transplanted to Nude Mice

2015 ◽  
pp. 155-158
Author(s):  
J�rgen Rygaard ◽  
Niels Gr�m ◽  
Vibeke Tromholt ◽  
Peter Samuelsen
Keyword(s):  
Wound Healing ◽  
Human Skin ◽  
Nude Mice ◽  
Wound Healing Model ◽  
Healing Model

Asiaticoside enhances normal human skin cell migration, attachment and growth in vitro wound healing model

Phytomedicine ◽  
2012 ◽  
Vol 19 (13) ◽  
pp. 1223-1227 ◽  
Author(s):  
Jeong-Hyun Lee ◽  
Hye-Lee Kim ◽  
Mi Hee Lee ◽  
Kyung Eun You ◽  
Byeong-Ju Kwon ◽  
...  
Keyword(s):  
Wound Healing ◽  
Cell Migration ◽  
Human Skin ◽  
Normal Human Skin ◽  
Skin Cell ◽  
Normal Human ◽  
Wound Healing Model ◽  
Healing Model

scholarly journals Optimization of an ex vivo wound healing model in the adult human skin: Functional evaluation using photodynamic therapy

2015 ◽  
Vol 23 (5) ◽  
pp. 685-702 ◽  
Author(s):  
Jenifer Mendoza‐Garcia ◽  
Anil Sebastian ◽  
Teresa Alonso‐Rasgado ◽  
Ardeshir Bayat
Keyword(s):  
Wound Healing ◽  
Photodynamic Therapy ◽  
Human Skin ◽  
Ex Vivo ◽  
Functional Evaluation ◽  
Adult Human ◽  
Wound Healing Model ◽  
Adult Human Skin ◽  
Healing Model

A human skin culture system for a wound-healing model

2012 ◽  
Vol 15 (sup1) ◽  
pp. 102-103 ◽  
Author(s):  
A. Mitbauerová ◽  
G. Rolin ◽  
S. Robin ◽  
H. Tauzin ◽  
E. Jacquet ◽  
...  
Keyword(s):  
Wound Healing ◽  
Human Skin ◽  
Culture System ◽  
Skin Culture ◽  
Wound Healing Model ◽  
Healing Model

scholarly journals Angiogenesis Is Induced and Wound Size Is Reduced by Electrical Stimulation in an Acute Wound Healing Model in Human Skin

PLoS ONE ◽  
2015 ◽  
Vol 10 (4) ◽  
pp. e0124502 ◽  
Author(s):  
Sara Ud-Din ◽  
Anil Sebastian ◽  
Pamela Giddings ◽  
James Colthurst ◽  
Sigrid Whiteside ◽  
...  
Keyword(s):  
Wound Healing ◽  
Electrical Stimulation ◽  
Human Skin ◽  
Wound Size ◽  
Acute Wound ◽  
Wound Healing Model ◽  
Healing Model

096 A wound healing model in organotypic culture of human skin

1996 ◽  
Vol 12 (2) ◽  
pp. 197
Author(s):  
Y. Suzuki ◽  
K. Harii ◽  
N. Huh ◽  
T. Kuroki
Keyword(s):  
Wound Healing ◽  
Human Skin ◽  
Organotypic Culture ◽  
Wound Healing Model ◽  
Healing Model

scholarly journals Galvanic microparticles increase migration of human dermal fibroblasts in a wound-healing model via reactive oxygen species pathway

2014 ◽  
Vol 320 (1) ◽  
pp. 79-91 ◽  
Author(s):  
Nina Tandon ◽  
Elisa Cimetta ◽  
Aranzazu Villasante ◽  
Nicolette Kupferstein ◽  
Michael D. Southall ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Wound Healing ◽  
Reactive Oxygen ◽  
Dermal Fibroblasts ◽  
Oxygen Species ◽  
Human Dermal Fibroblasts ◽  
Wound Healing Model ◽  
Healing Model

scholarly journals Transcriptomic Analysis of a Diabetic Skin-Humanized Mouse Model Dissects Molecular Pathways Underlying the Delayed Wound Healing Response

Genes ◽  
2020 ◽  
Vol 12 (1) ◽  
pp. 47
Author(s):  
Carlos León ◽  
Francisco García-García ◽  
Sara Llames ◽  
Eva García-Pérez ◽  
Marta Carretero ◽  
...  
Keyword(s):  
Wound Healing ◽  
Functional Enrichment ◽  
Preclinical Model ◽  
Published Data ◽  
Diabetic Patients ◽  
Ulcer Formation ◽  
Histological Features ◽  
Depth Analysis ◽  
Wound Healing Model ◽  
Healing Model

Defective healing leading to cutaneous ulcer formation is one of the most feared complications of diabetes due to its consequences on patients’ quality of life and on the healthcare system. A more in-depth analysis of the underlying molecular pathophysiology is required to develop effective healing-promoting therapies for those patients. Major architectural and functional differences with human epidermis limit extrapolation of results coming from rodents and other small mammal-healing models. Therefore, the search for reliable humanized models has become mandatory. Previously, we developed a diabetes-induced delayed humanized wound healing model that faithfully recapitulated the major histological features of such skin repair-deficient condition. Herein, we present the results of a transcriptomic and functional enrichment analysis followed by a mechanistic analysis performed in such humanized wound healing model. The deregulation of genes implicated in functions such as angiogenesis, apoptosis, and inflammatory signaling processes were evidenced, confirming published data in diabetic patients that in fact might also underlie some of the histological features previously reported in the delayed skin-humanized healing model. Altogether, these molecular findings support the utility of such preclinical model as a valuable tool to gain insight into the molecular basis of the delayed diabetic healing with potential impact in the translational medicine field.

scholarly journals Morphological Evaluation of Wound Healing Events in the Excisional Wound Healing Model in Rats

BIO-PROTOCOL ◽  
2019 ◽  
Vol 9 (13) ◽  
Author(s):  
Ligia Estevão ◽  
Puebla Cassini-Vieira ◽  
Ana Greice Leite ◽  
Apolônia Bulhões ◽  
Lucíola da Barcelos ◽  
...  
Keyword(s):  
Wound Healing ◽  
Morphological Evaluation ◽  
Excisional Wound ◽  
Wound Healing Model ◽  
Healing Model

Sanativo Wound Healing Product Does Not Accelerate Reepithelialization in a Mouse Cutaneous Wound Healing Model

2017 ◽  
Vol 139 (2) ◽  
pp. 343-352 ◽  
Author(s):  
Clement D. Marshall ◽  
Michael S. Hu ◽  
Tripp Leavitt ◽  
Leandra A. Barnes ◽  
Alexander T. M. Cheung ◽  
...  
Keyword(s):  
Wound Healing ◽  
Cutaneous Wound Healing ◽  
Cutaneous Wound ◽  
Wound Healing Model ◽  
Healing Model
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