Evaluation of Treatment Plans Using Dose Volume Histograms

2015 ◽  
pp. 44-55 ◽  
Author(s):  
G. T. Y. Chen ◽  
C. A. Pelizzari ◽  
D. R. Spelbring ◽  
A. Awan
Keyword(s):  
Dose Volume Histograms ◽  
Dose Volume ◽  
Treatment Plans

A deep learning model to predict dose–volume histograms of organs at risk in radiotherapy treatment plans

2020 ◽  
Vol 47 (11) ◽  
pp. 5467-5481
Author(s):  
Zhiqiang Liu ◽  
Xinyuan Chen ◽  
Kuo Men ◽  
Junlin Yi ◽  
Jianrong Dai
Keyword(s):  
At Risk ◽  
Deep Learning ◽  
Organs At Risk ◽  
Learning Model ◽  
Dose Volume Histograms ◽  
Dose Volume ◽  
Treatment Plans ◽  
Deep Learning Model ◽  
Radiotherapy Treatment

Challenges and Differences in External Radiation Therapy for Retinoblastoma: From Standard Techniques to New Developments

2015 ◽  
Vol 103 (5) ◽  
pp. 438-442
Author(s):  
Ayşe Hiçsönmez ◽  
Yıldız Güney ◽  
Ayşen Dizman ◽  
Bahar Dirican ◽  
Yakup Arslan ◽  
...  
Keyword(s):  
Bone Growth ◽  
External Beam Radiotherapy ◽  
Intensity Modulated Radiotherapy ◽  
Target Volume ◽  
Dose Volume Histograms ◽  
Normal Tissues ◽  
Dose Volume ◽  
Significant Difference ◽  
Treatment Plans ◽  
External Radiation Therapy

Aims The purpose of this study is to calculate the treatment plans and to compare the dose distributions and dose-volume histograms (DVH) for 6 external radiotherapy techniques for the treatment of retinoblastoma as well as intensity-modulated radiotherapy (IMRT) and fractionated stereotactic radiotherapy (Cyberknife). Methods Treatment plans were developed using 6 techniques, including an en face electron technique (ET), an anterior and lateral wedge photon technique (LFT), a 3D conformal (6 fields) technique (CRT), an inverse plan IMRT, tomotherapy, and conventional focal stereotactic external beam radiotherapy with Cyberknife (SBRT). Dose volume analyses were carried out for each technique. Results All techniques except electron provided similar target coverage. When comparing conformal plan with IMRT and SBRT, there was no significant difference in planning target volume dose distribution. The mean volume of ipsilateral bony orbit received more than 20 Gy, a suggested threshold for bone growth inhibition. The V20 Gy was 73% for the ET, 57% for the LFT, 87% for the CRT, 65% for the IMRT, 66% for the tomotherapy, and 2.7% for the SBRT. Conclusions This work supports the potential use of IMRT and SBRT to spare normal tissues in these patients.

A comparison of proton and photon radiotherapy in reducing cardiac exposure for patients receiving radiation therapy for distal and esophagogastric junction cancer.

2014 ◽  
Vol 32 (3_suppl) ◽  
pp. 167-167
Author(s):  
Ted Chen-Tai Ling ◽  
Jerry Monroe Slater ◽  
Rachel Mifflin ◽  
Prashanth Nookala ◽  
Roger Grove ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Esophagogastric Junction ◽  
Intensity Modulated Radiotherapy ◽  
Target Volume ◽  
Dose Distributions ◽  
Dose Volume Histograms ◽  
Dose Volume ◽  
Partial Volumes ◽  
Treatment Plans ◽  
Adequate Coverage

167 Background: Recent studies indicate that radiation exposure to heart may have a greater impact on perioperative cardiac morbidities than do other clinical factors. The purpose of this study is to investigate dose distributions of proton and photon treatment plans in patients (pts) with distal and esophagogastric junction (GEJ) carcinoma, focusing specifically on dose reduction to cardiac structures. Methods: Ten pts between 2010 and 2013 were included in this study. Three separate plans were generated for each patient: 3D proton plan, 3D photon plan, and Intensity modulated radiotherapy (IMRT) photon plan. The clinical target volume (CTV) consisted of the pre-operative extent of tumor plus a 10mm manual expansion in all directions. The planning target volume (PTV) was generated by a further expansion on the CTV ranging from 10-15mm. A dose of 50.4Gy given in 28 fractions was delivered to the PTV. All plans were optimized to allow 90% isodose coverage of at least 95% of the PTV. Dose-volume histograms were calculated and analyzed in order to compare plans between the three modalities. ANOVA and two-tailed paired t-tests were performed for all data parameters. Results: The 3D proton plans showed decreased dose to partial volumes of the entire heart, arteries, valves, atria, and ventricles in comparison to both the IMRT and 3D photon plans (see Table). The IMRT plans showed decreased dose delivered to the LAD artery, pericardium, and atria in comparison to the 3D photon plans (see Table). Conclusions: For pts receiving radiation therapy for distal esophageal and GEJ cancer, proton plans are technically feasible with adequate coverage while resulting in lower dose to cardiac structures. This may result in decreased cardiac toxicity and less complications in a multimodality setting. [Table: see text]

scholarly journals A computational tool for the efficient analysis of dose-volume histograms for radiation therapy treatment plans

2010 ◽  
Vol 11 (1) ◽  
pp. 137-157 ◽  
Author(s):  
Anil Pyakuryal ◽  
W. Kenji Myint ◽  
Mahesh Gopalakrishnan ◽  
Sunyoung Jang ◽  
Jerilyn A. Logemann ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Computational Tool ◽  
Dose Volume Histograms ◽  
Dose Volume ◽  
Treatment Plans ◽  
Therapy Treatment

Evaluation of lung treatment plans using dose volume histograms

1986 ◽  
Vol 12 ◽  
pp. 112-113
Author(s):  
G.T.Y. Chen ◽  
F.T. Kuchnir ◽  
C.A. Pelizzari ◽  
C.S. Reft ◽  
D.R. Spelbring ◽  
...  
Keyword(s):  
Dose Volume Histograms ◽  
Dose Volume ◽  
Treatment Plans

Comparison between different boost dose delivery techniques to the tumor bed of right sided breast cancer patients.

2017 ◽  
Vol 13 (1) ◽  
pp. 4605-4617
Author(s):  
Aly Mahmoud El-Hdidy
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Target Location ◽  
Breast Cancer Patients ◽  
Photon Beams ◽  
Lung Dose ◽  
Dose Volume Histograms ◽  
Tumor Bed ◽  
Boost Dose ◽  
Treatment Plans

Comparisons between three different techniques by which the boost dose was delivered to the tumor bed were carried out , aiming to present the best technique of treatment for right breast cancer patients.In this study, ten right sided breast cancer computed tomography (CT) scans were selected for ten early right breast cancer patients. We made three different treatment plans for each patient CT using three different irradiation techniques to deliver a prescribed boost dose of 10 Gy in 5 fractions to the boost PTV. In the first technique, two tangential photon beams were used, in the second technique we, two oblique photon beams were used and in the third technique, a single electron beam was used. The comparative analyses between the three techniques were performed by comparing the boost PTV- dose volume histograms (DVHs), the ipsilateral breast (right breast) DVHs, the ipsilateral lung (right lung) DVHs and the heart DVHs of the three techniques for each patient. Furthermore the dose that covering 100% , 95% of the volume (D100% , D95%) and the volume covered by 95% of the dose (V95%)of  the boost PTV of all techniques, were calculated for each patient to investigate the dose coverage of the target.Results showed that there were variations of the dose received by tumor bed, right breast and OARs depending on the technique used and the target location and size. A decrease of D100% than 90% of the prescribed dose was observed with the 3rd technique for patients 8, 9 and 10, and was observed with the 2nd technique for patient 5. A reduction of right breast dose was observed when the 3rd technique was use in comparison with the 1st and the 2nd techniques for patients 1, 2, 3, 4, 6 and 8.  Also reduction of right breast was observed when the 2nd technique used in comparison with 1st technique. An increase of lung dose was observed with the 3rd technique for patients 1, 2, 5 and 6, also was observed with 2nd technique in patient 3, 5 and 7. A decrease of lung dose was observed with the 1st technique for patients 2, 4, 5, 6, 7, 8 and 9An individualized treatment, several plans using different irradiation techniques should be developed for each patient individually to reach the best boost PTV dose coverage with minimal OARs’ dose. 

Method of predicting the mean lung dose based on a patient׳s anatomy and dose-volume histograms

2017 ◽  
Vol 42 (1) ◽  
pp. 57-62 ◽  
Author(s):  
Anna Zawadzka ◽  
Marta Nesteruk ◽  
Beata Brzozowska ◽  
Paweł F. Kukołowicz
Keyword(s):  
Lung Dose ◽  
Dose Volume Histograms ◽  
Dose Volume ◽  
The Mean ◽  
Mean Lung Dose

Analysis of the Physical and Radiobiological Equivalence of the Calculated and Measured Dose Distributions for Prostate Stereotactic Radiotherapy

2021 ◽  
Vol 66 (3) ◽  
pp. 68-75
Author(s):  
E. Sukhikh ◽  
L. Sukhikh ◽  
A. Vertinsky ◽  
P. Izhevsky ◽  
I. Sheino ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Dose Distribution ◽  
Three Dimensional ◽  
Anterior Wall ◽  
Dose Distributions ◽  
Stereotactic Radiation ◽  
Dose Volume Histograms ◽  
Dose Volume ◽  
Gamma Index ◽  
Measured Dose

Purpose: Carrying out the analysis of the physical and radiobiological equivalence of dose distributions obtained during the planning of hypofractionated stereotactic radiation therapy of the prostate cancer and verification using a three-dimensional cylindrical dosimeter. Material and Methods: Based on the anatomical data of twelve patients diagnosed with prostate carcinoma, stage T2N0M0 with low risk, plans were developed for stereotactic radiation therapy with volumetric modulates arc therapy (VMAT). The dose per fraction was 7,25 Gy for 5 fractions (total dose 36,25 Gy) with a normal photon energy of 10 MV. The developed plans were verified using a three-dimensional cylindrical ArcCHECK phantom. During the verification process, the three-dimensional dose distribution in the phantom was measured, based on which the values of the three-dimensional gamma index and the dose–volume histogram within each contoured anatomical structures were calculated with 3DVH software. The gamma index value γ (3 %, 2 mm, GN) at a threshold equal to 20 % of the dose maximum of the plan and the percentage of coincidence of points at least 95 % was chosen as a criterion of physical convergence of the calculated and measured dose distribution according to the recommendations of AAPM TG-218. To analyze the radiobiological equivalence of the calculated and measured dose distribution, the local control probability (TCP) and normal tissue complication probability (NTCP) criteria were used based on the calculated and measured dose–volume histograms. Contours of the target (PTV) and the anterior wall of the rectum were used for the analysis. The approach based on the concept of equivalent uniform dose (EUD) by A. Niemierko was used to calculate the values of TCP/NTCP criteria. Results: The results of physical convergence of plans for all patients on the contour of the whole body were higher than 95 % for the criteria γ (3 %, 2 mm, GN). The convergence along the PTV contour is in the range (75.5–95.2)%. The TCP and NTCP values obtained from the measured dose-volume histograms were higher than the planned values for all patients. It was found that the accelerator delivered a slightly higher dose to the PTV and the anterior wall of the rectum than originally planned. Conclusion: The capabilities of modern dosimetric equipment allow us move to the verification of treatment plans based on the analysis of TCP / NTCP radiobiological equivalence, taking into account the individual characteristics of the patient and the capabilities of radiation therapy equipment.

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